Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor
Hariri, Benjamin M., McMahon, Derek B., Chen, Bei, Freund, Jenna R., Mansfield, Corrine J., Doghramji, Laurel J., Adappa, Nithin D., Palmer, James N., Kennedy, David W., Reed, Danielle R., Jiang, Peihua, Lee, Robert J.
Published in The Journal of biological chemistry (19.05.2017)
Published in The Journal of biological chemistry (19.05.2017)
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Savory Signaling: T1R Umami Receptor Modulates Endoplasmic Reticulum Calcium Store Content and Release Dynamics in Airway Epithelial Cells
McMahon, Derek B, Jolivert, Jennifer F, Kuek, Li Eon, Adappa, Nithin D, Palmer, James N, Lee, Robert J
Published in Nutrients (18.01.2023)
Published in Nutrients (18.01.2023)
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Journal Article
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma
Carey, Ryan M., McMahon, Derek B., Miller, Zoey A., Kim, TaeBeom, Rajasekaran, Karthik, Gopallawa, Indiwari, Newman, Jason G., Basu, Devraj, Nead, Kevin T., White, Elizabeth A., Lee, Robert J.
Published in Molecular oncology (01.04.2022)
Published in Molecular oncology (01.04.2022)
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Journal Article
Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections
Kuek, Li Eon, McMahon, Derek B, Ma, Ray Z, Miller, Zoey A, Jolivert, Jennifer F, Adappa, Nithin D, Palmer, James N, Lee, Robert J
Published in Pharmaceuticals (Basel, Switzerland) (06.04.2022)
Published in Pharmaceuticals (Basel, Switzerland) (06.04.2022)
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Journal Article
Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells
Lee, Robert J, Hariri, Benjamin M, McMahon, Derek B, Chen, Bei, Doghramji, Laurel, Adappa, Nithin D, Palmer, James N, Kennedy, David W, Jiang, Peihua, Margolskee, Robert F, Cohen, Noam A
Published in Science signaling (05.09.2017)
Published in Science signaling (05.09.2017)
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Neuropeptide regulation of secretion and inflammation in human airway gland serous cells
McMahon, Derek B, Carey, Ryan M, Kohanski, Michael A, Tong, Charles C L, Papagiannopoulos, Peter, Adappa, Nithin D, Palmer, James N, Lee, Robert J
Published in The European respiratory journal (01.04.2020)
Published in The European respiratory journal (01.04.2020)
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Journal Article
The bitter end: T2R bitter receptor agonists elevate nuclear calcium and induce apoptosis in non-ciliated airway epithelial cells
McMahon, Derek B., Kuek, Li Eon, Johnson, Madeline E., Johnson, Paige O., Horn, Rachel L.J., Carey, Ryan M., Adappa, Nithin D., Palmer, James N., Lee, Robert J.
Published in Cell calcium (Edinburgh) (01.01.2022)
Published in Cell calcium (Edinburgh) (01.01.2022)
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PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa
McMahon, Derek B, Carey, Ryan M, Kohanski, Michael A, Adappa, Nithin D, Palmer, James N, Lee, Robert J
Published in American journal of physiology. Lung cellular and molecular physiology (01.05.2021)
Published in American journal of physiology. Lung cellular and molecular physiology (01.05.2021)
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Journal Article
Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
Miller, Zoey A., Mueller, Arielle, Kim, TaeBeom, Jolivert, Jennifer F., Ma, Ray Z., Muthuswami, Sahil, Park, April, McMahon, Derek B., Nead, Kevin T., Carey, Ryan M., Lee, Robert J.
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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Journal Article
Protease-activated receptor 2 activates airway apical membrane chloride permeability and increases ciliary beating
McMahon, Derek B, Workman, Alan D, Kohanski, Michael A, Carey, Ryan M, Freund, Jenna R, Hariri, Benjamin M, Chen, Bei, Doghramji, Laurel J, Adappa, Nithin D, Palmer, James N, Kennedy, David W, Lee, Robert J
Published in The FASEB journal (01.01.2018)
Published in The FASEB journal (01.01.2018)
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Cilia stimulatory and antibacterial activities of bitter receptor agonist diphenhydramine: insights into potential complimentary strategies for CF nasal infections
Li Eon Kuek, Mcmahon, Derek B, Ma, Ray Z, Miller, Zoey A, Jolivert, Jennifer F, Adappa, Nithin D, Palmer, James N, Lee, Robert J
Published in bioRxiv (02.02.2022)
Published in bioRxiv (02.02.2022)
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Inverse regulation of secretion and inflammation in human airway gland serous cells by neuropeptides upregulated in allergy and asthma
Mcmahon, Derek B, Kohanski, Michael A, Tong, Charles Cl, Papagiannopoulos, Peter, Adappa, Nithin D, Palmer, James N, Lee, Robert J
Published in bioRxiv (10.05.2019)
Published in bioRxiv (10.05.2019)
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