Filaggrin Mutations Associated with Skin and Allergic Diseases
Irvine, Alan D, McLean, W.H. Irwin, Leung, Donald Y.M
Published in The New England journal of medicine (06.10.2011)
Published in The New England journal of medicine (06.10.2011)
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Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity
Kezic, S., O’Regan, G. M., Yau, N., Sandilands, A., Chen, H., Campbell, L. E., Kroboth, K., Watson, R., Rowland, M., Irwin McLean, W. H., Irvine, A. D.
Published in Allergy (Copenhagen) (01.07.2011)
Published in Allergy (Copenhagen) (01.07.2011)
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Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis
Fleury, Orla M, McAleer, Maeve A, Feuillie, Cécile, Formosa-Dague, Cécile, Sansevere, Emily, Bennett, Désirée E, Towell, Aisling M, McLean, W H Irwin, Kezic, Sanja, Robinson, D Ashley, Fallon, Padraic G, Foster, Timothy J, Dufrêne, Yves F, Irvine, Alan D, Geoghegan, Joan A
Published in Infection and immunity (01.06.2017)
Published in Infection and immunity (01.06.2017)
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Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year
Kennedy, Elizabeth A., BS, Connolly, Jennifer, MSc, Hourihane, Jonathan O'B., DM, Fallon, Padraic G., PhD, McLean, W.H. Irwin, DSc, FRS, Murray, Deirdre, PhD, Jo, Jay-Hyun, PhD, Segre, Julia A., PhD, Kong, Heidi H., MD, MHSc, Irvine, Alan D., MD, DSc
Published in Journal of allergy and clinical immunology (01.01.2017)
Published in Journal of allergy and clinical immunology (01.01.2017)
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Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention
Simpson, Eric L., MD, MCR, Chalmers, Joanne R., PhD, Hanifin, Jon M., MD, Thomas, Kim S., PhD, Cork, Michael J., PhD, FRCP, McLean, W.H. Irwin, FRSE, FMedSci, Brown, Sara J., MRCP, MD, Chen, Zunqiu, MS, Chen, Yiyi, PhD, Williams, Hywel C., DSc, FMedSci
Published in Journal of allergy and clinical immunology (01.10.2014)
Published in Journal of allergy and clinical immunology (01.10.2014)
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Filaggrin in the frontline: role in skin barrier function and disease
Sandilands, Aileen, Sutherland, Calum, Irvine, Alan D, McLean, W.H. Irwin
Published in Journal of cell science (01.05.2009)
Published in Journal of cell science (01.05.2009)
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A lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays
McElroy, Stuart P, Nomura, Toshifumi, Torrie, Leah S, Warbrick, Emma, Gartner, Ulrike, Wood, Gavin, McLean, W H Irwin
Published in PLoS biology (01.06.2013)
Published in PLoS biology (01.06.2013)
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Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes
Schmitt, Jochen, MD, MPH, Schwarz, Kristin, MSc, Baurecht, Hansjörg, MSc, Hotze, Melanie, MSc, Fölster-Holst, Regina, MD, Rodríguez, Elke, PhD, Lee, Young A.E., MD, Franke, Andre, PhD, Degenhardt, Frauke, MSc, Lieb, Wolfgang, PhD, Gieger, Christian, PhD, Kabesch, Michael, MD, Nöthen, Markus M., MD, Irvine, Alan D., MD, McLean, W.H. Irwin, PhD, Deckert, Stefanie, MPH, Stephan, Victoria, Schwarz, Peter, MD, Aringer, Martin, MD, Novak, Natalija, MD, Weidinger, Stephan, MD, MaHM
Published in Journal of allergy and clinical immunology (01.01.2016)
Published in Journal of allergy and clinical immunology (01.01.2016)
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Atopic Dermatitis and Disease Severity Are the Main Risk Factors for Food Sensitization in Exclusively Breastfed Infants
Flohr, Carsten, Perkin, Michael, Logan, Kirsty, Marrs, Tom, Radulovic, Suzana, Campbell, Linda E., MacCallum, Stephanie F., Irwin McLean, W.H., Lack, Gideon
Published in Journal of investigative dermatology (01.02.2014)
Published in Journal of investigative dermatology (01.02.2014)
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Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year
Kelleher, Maeve, MB, Dunn-Galvin, Audrey, PhD, Hourihane, Jonathan O'B., DM, Murray, Deirdre, MD, Campbell, Linda E., BSc, McLean, W.H. Irwin, DSc, FRS, Irvine, Alan D., MD
Published in Journal of allergy and clinical immunology (01.04.2015)
Published in Journal of allergy and clinical immunology (01.04.2015)
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Skin barrier impairment at birth predicts food allergy at 2 years of age
Kelleher, Maeve M., MD, Dunn-Galvin, Audrey, PhD, Gray, Claire, RN, Murray, Deirdre M., MD, PhD, Kiely, Mairead, PhD, Kenny, Louise, PhD, McLean, W.H. Irwin, PhD, FRS, Irvine, Alan D., MD, PhD, Hourihane, Jonathan O'B., DM
Published in Journal of allergy and clinical immunology (01.04.2016)
Published in Journal of allergy and clinical immunology (01.04.2016)
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Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
Kezic, Sanja, PhD, O’Regan, Gráinne M., MRCPI, Lutter, René, PhD, Jakasa, Ivone, PhD, Koster, Ellen S., PhD, Saunders, Sean, BSc, Caspers, Peter, PhD, Kemperman, Patrick M.J.H., MD, Puppels, Gerwin J., PhD, Sandilands, Aileen, PhD, Chen, Huijia, PhD, Campbell, Linda E., BSc, Kroboth, Karin, MSc, Watson, Rosemarie, MD, Fallon, Padraic G., PhD, McLean, W. H. Irwin, DSc, FMedSci, Irvine, Alan D., MD, FRCPI
Published in Journal of allergy and clinical immunology (01.04.2012)
Published in Journal of allergy and clinical immunology (01.04.2012)
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Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations
Brough, Helen A., MSc, FRCPCH, Simpson, Angela, MD, PhD, Makinson, Kerry, MSc, Hankinson, Jenny, PhD, Brown, Sara, MD, Douiri, Abdel, PhD, Belgrave, Danielle C.M., MSc, Penagos, Martin, MD, MSc, Stephens, Alick C., PhD, McLean, W.H. Irwin, PhD, DSc, FRSE, FMedSci, Turcanu, Victor, PhD, Nicolaou, Nicolaos, MD, PhD, Custovic, Adnan, MD, PhD, Lack, Gideon, MD, FRCPCH
Published in Journal of allergy and clinical immunology (01.10.2014)
Published in Journal of allergy and clinical immunology (01.10.2014)
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The persistence of atopic dermatitis and filaggrin ( FLG ) mutations in a US longitudinal cohort
Margolis, David J., MD, PhD, Apter, Andrea J., MD, MSc, Gupta, Jayanta, MD, PhD, Hoffstad, Ole, MS, Papadopoulos, Maryte, BA, Campbell, Linda E., BA, Sandilands, Aileen, PhD, McLean, W.H. Irwin, PhD, DSc, Rebbeck, Tim R., PhD, Mitra, Nandita, PhD
Published in Journal of allergy and clinical immunology (01.10.2012)
Published in Journal of allergy and clinical immunology (01.10.2012)
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Gut microbiota development during infancy: Impact of introducing allergenic foods
Marrs, Tom, Jo, Jay-Hyun, Perkin, Michael R., Rivett, Damian W., Witney, Adam A., Bruce, Kenneth D., Logan, Kirsty, Craven, Joanna, Radulovic, Suzana, Versteeg, Serge A., van Ree, Ronald, McLean, W. H. Irwin, Strachan, David P., Lack, Gideon, Kong, Heidi H., Flohr, Carsten
Published in Journal of allergy and clinical immunology (01.02.2021)
Published in Journal of allergy and clinical immunology (01.02.2021)
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Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy
Brough, Helen A., MSc, FRCPCH, Liu, Andrew H., MD, Sicherer, Scott, MD, Makinson, Kerry, MSc, Douiri, Abdel, PhD, Brown, Sara J., MD, Stephens, Alick C., PhD, Irwin McLean, W.H., PhD, DSc, FRSE, FMedSci, Turcanu, Victor, PhD, Wood, Robert A., MD, Jones, Stacie M., MD, Burks, Wesley, MD, Dawson, Peter, PhD, Stablein, Donald, PhD, Sampson, Hugh, MD, Lack, Gideon, MD
Published in Journal of allergy and clinical immunology (01.01.2015)
Published in Journal of allergy and clinical immunology (01.01.2015)
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Systemic and stratum corneum biomarkers of severity in infant atopic dermatitis include markers of innate and T helper cell‐related immunity and angiogenesis
McAleer, M.A., Jakasa, I., Hurault, G., Sarvari, P., McLean, W.H.I., Tanaka, R.J., Kezic, S., Irvine, A.D.
Published in British journal of dermatology (1951) (01.03.2019)
Published in British journal of dermatology (1951) (01.03.2019)
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