Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals
Du, Wen, Wang, Junqiang, Kuo, Taiyi, Wang, Liheng, McKimpson, Wendy M, Son, Jinsook, Watanabe, Hitoshi, Kitamoto, Takumi, Lee, Yunkyoung, Creusot, Remi J, Ratner, Lloyd E, McCune, Kasi, Chen, Ya-Wen, Grubbs, Brendan H, Thornton, Matthew E, Fan, Jason, Sultana, Nishat, Diaz, Bryan S, Balasubramanian, Iyshwarya, Gao, Nan, Belvedere, Sandro, Accili, Domenico
Published in The Journal of clinical investigation (15.12.2022)
Published in The Journal of clinical investigation (15.12.2022)
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Diabetes treatment by conversion of gut epithelial cells to insulin‐producing cells
Accili, Domenico, Talchai, Shivatra C, Bouchi, Ryotaro, Lee, April Yun‐Kyoung, Du, Wen, Kitamoto, Takumi, McKimpson, Wendy M, Belvedere, Sandro, Lin, Hua V
Published in Journal of diabetes investigation (01.07.2024)
Published in Journal of diabetes investigation (01.07.2024)
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Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes
Kitamoto, Takumi, Lee, Yun-Kyoung, Sultana, Nishat, Watanabe, Hitoshi, McKimpson, Wendy M., Du, Wen, Fan, Jason, Diaz, Bryan, Lin, Hua V., Leibel, Rudolph L., Belvedere, Sandro, Accili, Domenico
Published in Molecular metabolism (Germany) (01.12.2022)
Published in Molecular metabolism (Germany) (01.12.2022)
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A myeloid tumor suppressor role for NOL3
Stanley, Robert F, Piszczatowski, Richard T, Bartholdy, Boris, Mitchell, Kelly, McKimpson, Wendy M, Narayanagari, Swathi, Walter, Dagmar, Todorova, Tihomira I, Hirsch, Cassandra, Makishima, Hideki, Will, Britta, McMahon, Christine, Gritsman, Kira, Maciejewski, Jaroslaw P, Kitsis, Richard N, Steidl, Ulrich
Published in The Journal of experimental medicine (06.03.2017)
Published in The Journal of experimental medicine (06.03.2017)
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The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth
McKimpson, Wendy M, Yuan, Ziqiang, Zheng, Min, Crabtree, Judy S, Libutti, Steven K, Kitsis, Richard N
Published in PloS one (28.12.2015)
Published in PloS one (28.12.2015)
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Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells
McKimpson, Wendy M, Spiegel, Sophia, Mukhanova, Maria, Kraakman, Michael, Du, Wen, Kitamoto, Takumi, Yu, Junjie, Deng, Zhaobin, Pajvani, Utpal, Accili, Domenico
Published in The Journal of cell biology (07.10.2024)
Published in The Journal of cell biology (07.10.2024)
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Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes
McKimpson, Wendy M., Chen, Yun, Irving, James A., Zheng, Min, Weinberger, Jeremy, Tan, Wilson Lek Wen, Tiang, Zenia, Jagger, Alistair M., Chua, Streamson C., Pessin, Jeffrey E., Foo, Roger S.-Y., Lomas, David A., Kitsis, Richard N.
Published in Developmental cell (22.03.2021)
Published in Developmental cell (22.03.2021)
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An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Suyama, Kimita, Yao, Jiahong, Liang, Huizhi, Benard, Outhiriaradjou, Loudig, Olivier D, Amgalan, Dulguun, McKimpson, Wendy M, Phillips, Greg R, Segall, Jeffrey, Wang, Yihong, Fineberg, Susan, Norton, Larry, Kitsis, Richard N, Hazan, Rachel B
Published in Cancer research (Chicago, Ill.) (01.01.2018)
Published in Cancer research (Chicago, Ill.) (01.01.2018)
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The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-cell Survival
MCKIMPSON, Wendy M, WEINBERGER, Jeremy, CZERSKI, Lech, MIN ZHENG, CROW, Michael T, PESSIN, Jeffrey E, CHUA, Streamson C, KITSIS, Richard N
Published in Diabetes (New York, N.Y.) (01.01.2013)
Published in Diabetes (New York, N.Y.) (01.01.2013)
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Journal Article
Calorie Restriction activates a gastric Notch-FOXO1 pathway to expand Ghrelin cells
McKimpson, Wendy M, Spiegel, Sophia, Mukhanova, Maria, Kraakman, Michael, Du, Wen, Kitamoto, Takumi, Yu, Junjie, Pajvani, Utpal, Accili, Domenico
Published in bioRxiv (07.03.2023)
Published in bioRxiv (07.03.2023)
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Cyb5r3 activation rescues secondary failure to sulfonylurea but not [beta]-cell dedifferentiation
Watanabe, Hitoshi, Asahara, Shun-ichiro, Son, Jinsook, McKimpson, Wendy M, de Cabo, Rafael, Accili, Domenico
Published in PloS one (09.02.2024)
Published in PloS one (09.02.2024)
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