A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
Adams, Sarah E., Purkiss, Andrew G., Knowles, Phillip P., Nans, Andrea, Briggs, David C., Borg, Annabel, Earl, Christopher P., Goodman, Kerry M., Nawrotek, Agata, Borg, Aaron J., McIntosh, Pauline B., Houghton, Francesca M., Kjær, Svend, McDonald, Neil Q.
Published in Structure (London) (01.07.2021)
Published in Structure (London) (01.07.2021)
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Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex
Kyrieleis, Otto J.P., McIntosh, Pauline B., Webb, Sarah R., Calder, Lesley J., Lloyd, Janette, Patel, Nisha A., Martin, Stephen R., Robinson, Carol V., Rosenthal, Peter B., Smerdon, Stephen J.
Published in Cell reports (Cambridge) (20.12.2016)
Published in Cell reports (Cambridge) (20.12.2016)
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Role of Calpain in the Formation of Human Papillomavirus Type 16 E1^E4 Amyloid Fibers and Reorganization of the Keratin Network
KHAN, Jameela, DAVY, Clare E, MCINTOSH, Pauline B, JACKSON, Deborah J, HINZ, Steven, QIAN WANG, DOORBAR, John
Published in Journal of Virology (01.10.2011)
Published in Journal of Virology (01.10.2011)
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Journal Article
Phosphorylation of the Human Papillomavirus Type 16 E1^E4 Protein at T57 by ERK Triggers a Structural Change That Enhances Keratin Binding and Protein Stability
Wang, Qian, Kennedy, Alan, Das, Papia, McIntosh, Pauline B, Howell, Steven A, Isaacson, Erin R, Hinz, Steven A, Davy, Clare, Doorbar, John
Published in Journal of Virology (01.04.2009)
Published in Journal of Virology (01.04.2009)
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Journal Article
Structural Analysis Reveals an Amyloid Form of the Human Papillomavirus Type 16 E1∧E4 Protein and Provides a Molecular Basis for Its Accumulation
MCINTOSH, Pauline B, MARTIN, Stephen R, ECCLESTON, John F, DOORBAR, John, JACKSON, Deborah J, KHAN, Jameela, ISAACSON, Erin R, CALDER, Lesley, RAJ, Kenneth, GRIFFIN, Heather M, QIAN WANG, LASKEY, Peter
Published in Journal of Virology (01.08.2008)
Published in Journal of Virology (01.08.2008)
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Journal Article
E1^E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epithelium
McIntosh, Pauline B, Laskey, Peter, Sullivan, Kate, Davy, Clare, Wang, Qian, Jackson, Deborah J, Griffin, Heather M, Doorbar, John
Published in Journal of cell science (15.08.2010)
Published in Journal of cell science (15.08.2010)
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Journal Article
Characterization of the DNA-Binding Domains from the Yeast Cell-Cycle Transcription Factors Mbp1 and Swi4
Taylor, Ian A, McIntosh, Pauline B, Pala, Preshna, Treiber, Monika K, Howell, Steven, Lane, Andrew N, Smerdon, Stephen J
Published in Biochemistry (Easton) (11.04.2000)
Published in Biochemistry (Easton) (11.04.2000)
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Journal Article
High-Resolution Solution Structure of Human Intestinal Trefoil Factor and Functional Insights from Detailed Structural Comparisons with the Other Members of the Trefoil Family of Mammalian Cell Motility Factors
Lemercinier, Xavier, Muskett, Frederick W, Cheeseman, Bruce, McIntosh, Pauline B, Thim, Lars, Carr, Mark D
Published in Biochemistry (Easton) (14.08.2001)
Published in Biochemistry (Easton) (14.08.2001)
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Journal Article
Solution Structure of the B-Myb DNA-Binding Domain: A Possible Role for Conformational Instability of the Protein in DNA Binding and Control of Gene Expression
McIntosh, Pauline B, Frenkiel, Tom A, Wollborn, Ute, McCormick, John E, Klempnauer, Karl-Heinz, Feeney, James, Carr, Mark D
Published in Biochemistry (Easton) (07.07.1998)
Published in Biochemistry (Easton) (07.07.1998)
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Journal Article
The influence of DNA binding on the backbone dynamics of the yeast cell-cycle protein Mbp1
McIntosh, P B, Taylor, I A, Frenkiel, T A, Smerdon, S J, Lane, A N
Published in Journal of biomolecular NMR (01.03.2000)
Published in Journal of biomolecular NMR (01.03.2000)
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Journal Article
Phosphorylation of the Human Papillomavirus Type 16 E14 Protein at T57 by ERK Triggers a Structural Change That Enhances Keratin Binding and Protein Stability
Wang, Qian, Kennedy, Alan, Das, Papia, McIntosh, Pauline B, Howell, Steven A, Isaacson, Erin R, Hinz, Steven A, Davy, Clare, Doorbar, John
Published in Journal of virology (01.04.2009)
Published in Journal of virology (01.04.2009)
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Journal Article
Letter to the Editor: 1H, 15N and 13C assignments of the DNA binding domain of transcription factor Mbp1 from S. cerevisiae in both its free and the DNA bound forms, and 1H assignments of the free DNA
Mcintosh, Pauline B, Taylor, Ian A, Smerdon, Steven J, Frenkiel, Thomas A, Lane, Andrew N
Published in Journal of biomolecular NMR (01.04.1999)
Published in Journal of biomolecular NMR (01.04.1999)
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Journal Article
A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
Adams, Sarah E, Purkiss, Andrew G, Knowles, Phillip P, Nans, Andrea, Briggs, David C, Borg, Annabel, Earl, Christopher P, Goodman, Kerry M, Nawrotek, Agata, Borg, Aaron J, Mcintosh, Pauline B, Houghton, Francesca M, Kjær, Svend, Mcdonald, Neil Q
Published in bioRxiv (13.09.2020)
Published in bioRxiv (13.09.2020)
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Paper
Structure of the B-Myb DNA-binding domain in solution and evidence for multiple conformations in the region of repeat-2 involved in DNA binding: implications for sequence-specific DNA binding by Myb proteins
Carr, M D, Wollborn, U, McIntosh, P B, Frenkiel, T A, McCormick, J E, Bauer, C J, Klempnauer, K H, Feeney, J
Published in European journal of biochemistry (01.02.1996)
Published in European journal of biochemistry (01.02.1996)
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Journal Article
Structure of the B‐Myb DNA‐binding Domain in Solution and Evidence for Multiple Conformations in the Region of Repeat‐2 Involved in DNA Binding
Carr, Mark D., Wollborn, Ute, McIntosh, Pauline B., Frenkiel, Tom A., McCormick, John E., Bauer, Christopher J., Klempnauer, Karl‐Heinz, Feeney, James
Published in European journal of biochemistry (01.02.1996)
Published in European journal of biochemistry (01.02.1996)
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Journal Article