Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization
Whitaker, Gina M, Lynn, Francis C, McIntosh, Christopher H S, Accili, Eric A
Published in PloS one (07.03.2012)
Published in PloS one (07.03.2012)
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Journal Article
Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2
Kim, Su-Jin, Nian, Cuilan, Widenmaier, Scott, McIntosh, Christopher H. S.
Published in Molecular and Cellular Biology (01.03.2008)
Published in Molecular and Cellular Biology (01.03.2008)
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Journal Article
Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis
Pamir, Nathalie, Lynn, Francis C, Buchan, Alison M. J, Ehses, Jan, Hinke, Simon A, Pospisilik, J. Andrew, Miyawaki, Kazumasa, Yamada, Yuichiro, Seino, Yutaka, McIntosh, Christopher H. S, Pederson, Raymond A
Published in American journal of physiology: endocrinology and metabolism (01.05.2003)
Published in American journal of physiology: endocrinology and metabolism (01.05.2003)
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Journal Article
Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
Shu, Luan, Matveyenko, Aleksey V., Kerr-Conte, Julie, Cho, Jae-Hyoung, McIntosh, Christopher H.S., Maedler, Kathrin
Published in Human molecular genetics (01.07.2009)
Published in Human molecular genetics (01.07.2009)
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Journal Article
Sitagliptin (MK0431) Inhibition of Dipeptidyl Peptidase IV Decreases Nonobese Diabetic Mouse CD4+ T-Cell Migration Through Incretin-Dependent and -Independent Pathways
KIM, Su-Jin, NIAN, Cuilan, MCINTOSH, Christopher H. S
Published in Diabetes (New York, N.Y.) (01.07.2010)
Published in Diabetes (New York, N.Y.) (01.07.2010)
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Journal Article
A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control
Widenmaier, Scott B, Kim, Su-Jin, Yang, Gary K, De Los Reyes, Thomas, Nian, Cuilan, Asadi, Ali, Seino, Yutaka, Kieffer, Timothy J, Kwok, Yin Nam, McIntosh, Christopher H S
Published in PloS one (09.03.2010)
Published in PloS one (09.03.2010)
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Journal Article
Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase
Ehses, Jan A, Casilla, Vanbric R, Doty, Tim, Pospisilik, J. Andrew, Winter, Kyle D, Demuth, Hans-Ulrich, Pederson, Raymond A, McIntosh, Christopher H. S
Published in Endocrinology (Philadelphia) (01.10.2003)
Published in Endocrinology (Philadelphia) (01.10.2003)
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Journal Article
Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival
McIntosh, Christopher H S, Kim, Su-Jin, Doudet, Doris J, Studenov, Andrei R, Nian, Cuilan, Ruth, Thomas J, Gambhir, Sanjiv Sam
Published in Nature medicine (01.12.2006)
Published in Nature medicine (01.12.2006)
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Journal Article
Activation of Lipoprotein Lipase by Glucose-dependent Insulinotropic Polypeptide in Adipocytes: A ROLE FOR A PROTEIN KINASE B, LKB1, AND AMP-ACTIVATED PROTEIN KINASE CASCADE
Kim, Su-Jin, Nian, Cuilan, McIntosh, Christopher H.S
Published in The Journal of biological chemistry (23.03.2007)
Published in The Journal of biological chemistry (23.03.2007)
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Journal Article
Suppression of p38 MAPK and JNK via Akt-mediated Inhibition of Apoptosis Signal-regulating Kinase 1 Constitutes a Core Component of the β-Cell Pro-survival Effects of Glucose-dependent Insulinotropic Polypeptide
Widenmaier, Scott B., Ao, Ziliang, Kim, Su-Jin, Warnock, Garth, McIntosh, Christopher H.S.
Published in The Journal of biological chemistry (30.10.2009)
Published in The Journal of biological chemistry (30.10.2009)
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Journal Article
Glucose-Dependent Insulinotropic Polypeptide (Gastric Inhibitory Polypeptide; GIP)
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Book Chapter
Journal Article
Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat
Piteau, Shalea, Olver, Amy, Kim, Su-Jin, Winter, Kyle, Pospisilik, John Andrew, Lynn, Francis, Manhart, Susanne, Demuth, Hans-Ulrich, Speck, Madeleine, Pederson, Raymond A., McIntosh, Christopher H.S.
Published in Biochemical and biophysical research communications (03.11.2007)
Published in Biochemical and biophysical research communications (03.11.2007)
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