Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex
Choo, Xin Yi, McInnes, Lachlan E., Grubman, Alexandra, Wasielewska, Joanna M., Belaya, Irina, Burrows, Emma, Quek, Hazel, Martín, Jorge Cañas, Loppi, Sanna, Sorvari, Annika, Rait, Dzhessi, Powell, Andrew, Duncan, Clare, Liddell, Jeffrey R., Tanila, Heikki, Polo, Jose M., Malm, Tarja, Kanninen, Katja M., Donnelly, Paul S., White, Anthony R.
Published in International journal of molecular sciences (14.09.2022)
Published in International journal of molecular sciences (14.09.2022)
Get full text
Journal Article
Microglial ferroptotic stress causes non-cell autonomous neuronal death
Liddell, Jeffrey R, Hilton, James B W, Kysenius, Kai, Billings, Jessica L, Nikseresht, Sara, McInnes, Lachlan E, Hare, Dominic J, Paul, Bence, Mercer, Stephen W, Belaidi, Abdel A, Ayton, Scott, Roberts, Blaine R, Beckman, Joseph S, McLean, Catriona A, White, Anthony R, Donnelly, Paul S, Bush, Ashley I, Crouch, Peter J
Published in Molecular neurodegeneration (05.02.2024)
Published in Molecular neurodegeneration (05.02.2024)
Get full text
Journal Article
CuII(atsm) Attenuates Neuroinflammation
Choo, Xin Yi, Liddell, Jeffrey R., Huuskonen, Mikko T., Grubman, Alexandra, Moujalled, Diane, Roberts, Jessica, Kysenius, Kai, Patten, Lauren, Quek, Hazel, Oikari, Lotta E., Duncan, Clare, James, Simon A., McInnes, Lachlan E., Hayne, David J., Donnelly, Paul S., Pollari, Eveliina, Vähätalo, Suvi, Lejavová, Katarína, Kettunen, Mikko I., Malm, Tarja, Koistinaho, Jari, White, Anthony R., Kanninen, Katja M.
Published in Frontiers in neuroscience (24.09.2018)
Published in Frontiers in neuroscience (24.09.2018)
Get full text
Journal Article
Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies
McKenzie-Nickson, Simon, Chan, Jacky, Perez, Keyla, Hung, Lin W, Cheng, Lesley, Sedjahtera, Amelia, Gunawan, Lydia, Adlard, Paul A, Hayne, David J, McInnes, Lachlan E, Donnelly, Paul S, Finkelstein, David I, Hill, Andrew F, Barnham, Kevin J
Published in ACS chemical neuroscience (21.11.2018)
Published in ACS chemical neuroscience (21.11.2018)
Get full text
Journal Article
Copper bis(thiosemicarbazone) complexes modulate P‐glycoprotein expression and function in human brain microvascular endothelial cells
Pyun, Jae, McInnes, Lachlan E., Donnelly, Paul S., Mawal, Celeste, Bush, Ashley I., Short, Jennifer L., Nicolazzo, Joseph A.
Published in Journal of neurochemistry (01.08.2022)
Published in Journal of neurochemistry (01.08.2022)
Get full text
Journal Article
A Bivalent Inhibitor of Prostate Specific Membrane Antigen Radiolabeled with Copper‐64 with High Tumor Uptake and Retention
Zia, Nicholas A., Cullinane, Carleen, Van Zuylekom, Jessica K., Waldeck, Kelly, McInnes, Lachlan E., Buncic, Gojko, Haskali, Mohammad B., Roselt, Peter D., Hicks, Rodney J., Donnelly, Paul S.
Published in Angewandte Chemie International Edition (14.10.2019)
Published in Angewandte Chemie International Edition (14.10.2019)
Get full text
Journal Article
Potential Diagnostic Imaging of Alzheimer’s Disease with Copper-64 Complexes That Bind to Amyloid‑β Plaques
McInnes, Lachlan E, Noor, Asif, Kysenius, Kai, Cullinane, Carleen, Roselt, Peter, McLean, Catriona A, Chiu, Francis C. K, Powell, Andrew K, Crouch, Peter J, White, Jonathan M, Donnelly, Paul S
Published in Inorganic chemistry (04.03.2019)
Published in Inorganic chemistry (04.03.2019)
Get full text
Journal Article
Inert Transition Metal Ion Complexes in Organic Synthesis: Protection and Activation
Donnelly, Paul S, Harrowfield, Jack M, Koutsantonis, George A, Lengkeek, Nigel A, Ling, Irene, Nealon, Gareth L, McInnes, Lachlan E, Skelton, Brian W, Sobolev, Alexandre N, White, Allan H, White, Jonathan M
Published in Chemistry, an Asian journal (15.09.2023)
Published in Chemistry, an Asian journal (15.09.2023)
Get full text
Journal Article
Identification of the Side Products That Diminish the Yields of the Monoamidated Product in Metal-Catalyzed C–H Amidation of 2‑Phenylpyridine with Arylisocyanates
McKay, Alasdair I, Altalhi, Weam A. O, McInnes, Lachlan E, Czyz, Milena L, Canty, Allan J, Donnelly, Paul S, O’Hair, Richard A. J
Published in Journal of organic chemistry (21.02.2020)
Published in Journal of organic chemistry (21.02.2020)
Get full text
Journal Article
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background
Lum, Jeremy S., Brown, Mikayla L., Farrawell, Natalie E., McAlary, Luke, Ly, Diane, Chisholm, Christen G., Snow, Josh, Vine, Kara L., Karl, Tim, Kreilaus, Fabian, McInnes, Lachlan E., Nikseresht, Sara, Donnelly, Paul S., Crouch, Peter J., Yerbury, Justin J.
Published in Scientific reports (29.09.2021)
Published in Scientific reports (29.09.2021)
Get full text
Journal Article
Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P‑Glycoprotein Mediated Efflux
Acevedo, Karla M, Hayne, David J, McInnes, Lachlan E, Noor, Asif, Duncan, Clare, Moujalled, Diane, Volitakis, Irene, Rigopoulos, Angela, Barnham, Kevin J, Villemagne, Victor L, White, Anthony R, Donnelly, Paul S
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
Get full text
Journal Article
Therapeutic Efficacy of a Bivalent Inhibitor of Prostate-Specific Membrane Antigen Labeled with 67Cu
McInnes, Lachlan E, Cullinane, Carleen, Roselt, Peter D, Jackson, Susan, Blyth, Benjamin J, van Dam, Ellen M, Zia, Nicholas A, Harris, Matthew J, Hicks, Rodney J, Donnelly, Paul S
Published in The Journal of nuclear medicine (1978) (01.06.2021)
Published in The Journal of nuclear medicine (1978) (01.06.2021)
Get full text
Journal Article
Therapeutic Efficacy of a Bivalent Inhibitor of Prostate-Specific Membrane Antigen Labeled with 67 Cu
McInnes, Lachlan E, Cullinane, Carleen, Roselt, Peter D, Jackson, Susan, Blyth, Benjamin J, van Dam, Ellen M, Zia, Nicholas A, Harris, Matthew J, Hicks, Rodney J, Donnelly, Paul S
Published in Journal of Nuclear Medicine (01.06.2021)
Published in Journal of Nuclear Medicine (01.06.2021)
Get full text
Journal Article
Patient-Derived Blood-Brain Barrier Model for Screening Copper Bis(thiosemicarbazone) Complexes as Potential Therapeutics in Alzheimer’s Disease
Wasielewska, Joanna M., Szostak, Kathryn, McInnes, Lachlan E., Quek, Hazel, Chaves, Juliana C. S., Liddell, Jeffrey R., Koistinaho, Jari, Oikari, Lotta E., Donnelly, Paul S., White, Anthony R.
Published in ACS chemical neuroscience (03.04.2024)
Published in ACS chemical neuroscience (03.04.2024)
Get full text
Journal Article
The Copper bis(thiosemicarbazone) Complex CuII(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu
Huuskonen, Mikko T., Tuo, Qing-zhang, Loppi, Sanna, Dhungana, Hiramani, Korhonen, Paula, McInnes, Lachlan E., Donnelly, Paul S., Grubman, Alexandra, Wojciechowski, Sara, Lejavova, Katarina, Pomeshchik, Yuriy, Periviita, Laura, Kosonen, Lotta, Giordano, Martina, Walker, Frederick R., Liu, Rong, Bush, Ashley I., Koistinaho, Jari, Malm, Tarja, White, Anthony R., Lei, Peng, Kanninen, Katja M.
Published in Neurotherapeutics (01.04.2017)
Published in Neurotherapeutics (01.04.2017)
Get full text
Journal Article
A Copper Complex of a Thiosemicarbazone-Pyridylhydrazone Ligand Containing a Vinylpyridine Functional Group as a Potential Imaging Agent for Amyloid-beta Plaques
McInnes, Lachlan E., Noor, Asif, Roselt, Peter D., McLean, Catriona A., White, Jonathan M., Donnelly, Paul S.
Published in Australian journal of chemistry (01.01.2019)
Published in Australian journal of chemistry (01.01.2019)
Get full text
Journal Article
Bifunctional (64)Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography
Paterson, Brett M, Buncic, Gojko, McInnes, Lachlan E, Roselt, Peter, Cullinane, Carleen, Binns, David S, Jeffery, Charmaine M, Price, Roger I, Hicks, Rodney J, Donnelly, Paul S
Published in Dalton transactions : an international journal of inorganic chemistry (21.03.2015)
Published in Dalton transactions : an international journal of inorganic chemistry (21.03.2015)
Get full text
Journal Article
A Bivalent Inhibitor of Prostate Specific Membrane Antigen Radiolabeled with Copper‐64 with High Tumor Uptake and Retention
Zia, Nicholas A., Cullinane, Carleen, Van Zuylekom, Jessica K., Waldeck, Kelly, McInnes, Lachlan E., Buncic, Gojko, Haskali, Mohammad B., Roselt, Peter D., Hicks, Rodney J., Donnelly, Paul S.
Published in Angewandte Chemie (14.10.2019)
Published in Angewandte Chemie (14.10.2019)
Get full text
Journal Article
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background
Lum, Jeremy S, Brown, Mikayla L, Farrawell, Natalie E, McAlary, Luke, Ly, Diane, Chisholm, Christen G, Snow, Josh, Vine, Kara L, Karl, Tim, Kreilaus, Fabian, McInnes, Lachlan E, Nikseresht, Sara, Donnelly, Paul S, Crouch, Peter J, Yerbury, Justin J
Published in Scientific reports (29.09.2021)
Get full text
Published in Scientific reports (29.09.2021)
Journal Article