An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers
Osorio, A, Pollán, M, Pita, G, Schmutzler, R K, Versmold, B, Engel, C, Meindl, A, Arnold, N, Preisler-Adams, S, Niederacher, D, Hofmann, W, Gadzicki, D, Jakubowska, A, Hamann, U, Lubinski, J, Toloczko-Grabarek, A, Cybulski, C, Debniak, T, Llort, G, Yannoukakos, D, Díez, O, Peissel, B, Peterlongo, P, Radice, P, Heikkinen, T, Nevanlinna, H, Mai, P L, Loud, J T, McGuffog, L, Antoniou, A C, Benitez, J
Published in British journal of cancer (16.09.2008)
Published in British journal of cancer (16.09.2008)
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Cancer Risks and Mortality in Heterozygous ATM Mutation Carriers
Thompson, Deborah, Duedal, Silvia, Kirner, Jennifer, McGuffog, Lesley, Last, James, Reiman, Anne, Byrd, Philip, Taylor, Malcolm, Easton, Douglas F.
Published in JNCI : Journal of the National Cancer Institute (01.06.2005)
Published in JNCI : Journal of the National Cancer Institute (01.06.2005)
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The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2
LAKHANI, Sunil R, DE VIJVER, Marc J, JACQUEMIER, Jocelyne, ANDERSON, Thomas J, OSIN, Peter P, MCGUFFOG, Lesley, EASTON, Douglas F
Published in Journal of clinical oncology (01.05.2002)
Published in Journal of clinical oncology (01.05.2002)
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Low-penetrance susceptibility to breast cancer due to CHEK21100delC in noncarriers of BRCA1 or BRCA2 mutations
Meijers-Heijboer, Hanne, van den Ouweland, Ans, Klijn, Jan, Wasielewski, Marijke, de Snoo, Anja, Oldenburg, Rogier, Hollestelle, Antoinette, Houben, Mark, Crepin, Ellen, van Veghel-Plandsoen, Monique, Elstrodt, Fons, van Duijn, Cornelia, Bartels, Carina, Meijers, Carel, Schutte, Mieke, McGuffog, Lesley, Thompson, Deborah, Easton, Douglas F, Sodha, Nayanta, Seal, Sheila, Barfoot, Rita, Mangion, Jon, Chang-Claude, Jenny, Eccles, Diana, Eeles, Rosalind, Evans, D Gareth, Houlston, Richard, Murday, Victoria, Narod, Steven, Peretz, Tamara, Peto, Julian, Phelan, Catherine, Zhang, Hong Xiang, Szabo, Csilla, Devilee, Peter, Goldgar, David, Futreal, P Andrew, Nathanson, Katherine L, Weber, Barbara L, Rahman, Nazneen, Stratton, Michael R
Published in Nature genetics (01.05.2002)
Published in Nature genetics (01.05.2002)
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Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers (vol 25, pg 432, 2017)
Walker, LC, Marquart, L, Pearson, JF, Wiggins, GAR, O'Mara, TA, Parsons, MT, Barrowdale, D, McGuffog, L, Dennis, J, Benitez, J
Published in EUROPEAN JOURNAL OF HUMAN GENETICS (2019)
Published in EUROPEAN JOURNAL OF HUMAN GENETICS (2019)
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Correction: Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers
Walker, Logan C, Marquart, Louise, Pearson, John F, Wiggins, George A R, O'Mara, Tracy A, Parsons, Michael T, Barrowdale, Daniel, McGuffog, Lesley, Dennis, Joe, Benitez, Javier, Slavin, Thomas P, Radice, Paolo, Frost, Debra, Godwin, Andrew K, Meindl, Alfons, Schmutzler, Rita Katharina, Isaacs, Claudine, Peshkin, Beth N, Caldes, Trinidad, Hogervorst, Frans B L, Lazaro, Conxi, Jakubowska, Anna, Montagna, Marco, Chen, Xiaoqing, Offit, Kenneth, Hulick, Peter J, Andrulis, Irene L, Lindblom, Annika, Nussbaum, Robert L, Nathanson, Katherine L, Chenevix-Trench, Georgia, Antoniou, Antonis C, Couch, Fergus J, Spurdle, Amanda B
Published in European journal of human genetics : EJHG (2019)
Published in European journal of human genetics : EJHG (2019)
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Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study
Jakubowska, A, Rozkrut, D, Hamann, U, Scott, R J, McGuffog, L, Healy, S, Sinilnikova, O M, Rennert, G, Lejbkowicz, F, Flugelman, A, Andrulis, I L, Glendon, G, Ozcelik, H, Thomassen, M, Paligo, M, Kantala, J, Aroer, B, von Wachenfeldt, A, Loman, N, Herbst, K, Kristoffersson, U, Rosenquist, R, Karlsson, P, Stenmark-Askmalm, M, Melin, B, Nathanson, K L, Domchek, S M, Byrski, T, Huzarski, T, Gronwald, J, Menkiszak, J, Cybulski, C, Serrano, P, Cajal, T R, Tsitlaidou, M, Benítez, J, Rookus, M, Kluijt, I, Boessenkool-Pape, J L, Meijers-Heijboer, H E J, Oosterwijk, J C, van Asperen, C J, Nelen, M R, van den Ouweland, A M W, Seynaeve, C, Easton, D F, Frost, D, Platte, R, Ellis, S D, Fineberg, E, Evans, D G, Lalloo, F, Eeles, R, Jacobs, C, Adlard, J, Davidson, R, Eccles, D, Cole, T, Cook, J, Godwin, A, Bove, B, Stoppa-Lyonnet, D, Caux-Moncoutier, V, Belotti, M, Tirapo, C, Barjhoux, L, Pujol, P, Coupier, I, Peyrat, J-P, Vennin, P, Fricker, J-P, Venat-Bouvet, L, Johannsson, O Th, Isaacs, C, Schmutzler, R, Wappenschmidt, B, Meindl, A, Arnold, N, Varon-Mateeva, R, Niederacher, D, Sutter, C, Deissler, H, Preisler-Adams, S, Simard, J, Durocher, F, Beesley, J, Chen, X, Rebbeck, T, Couch, F, Wang, X, Lindor, N, Fredericksen, Z, Pankratz, V S, Peterlongo, P, Bonanni, B, Fortuzzi, S, Peissel, B, Szabo, C, Mai, P L, Loud, J T
Published in British journal of cancer (05.06.2012)
Published in British journal of cancer (05.06.2012)
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Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study
Jakubowska, A, Rozkrut, D, Antoniou, A, Hamann, U, Scott, RJ, McGuffog, L, Healy, S, Sinilnikova, OM, Rennert, G, Lejbkowicz, F
Published in British journal of cancer (2012)
Published in British journal of cancer (2012)
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Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
ENGEL, Christoph, VERSMOLD, Beatrix, GARETH EVANS, D, EELES, Rosalind, PATERSON, Joan, BREWER, Carole, MCGUFFOG, Lesley, ANTONIOU, Antonis C, STOPPA-LYONNET, Dominique, SINILNIKOVA, Olga M, BARJHOUX, Laure, FRENAY, Marc, WAPPENSCHMIDT, Barbara, MICHEL, Cécile, LEROUX, Dominique, DREYFUS, Helene, TOULAS, Christine, GLADIEFF, Laurence, UHRHAMMER, Nancy, BIGNON, Yves-Jean, MEINDL, Alfons, ARNOLD, Norbert, VARON-MATEEVA, Raymonda, SIMARD, Jacques, NIEDERACHER, Dieter, PREISLER-ADAMS, Sabine, KAST, Karin, DEISSLER, Helmut, SUTTER, Christian, GADZICKI, Dorothea, CHENEVIX-TRENCH, Georgia, SPURDLE, Amanda B, XIAOQING CHEN, BEESLEY, Jonathan, EASTON, Douglas F, OLSSON, Håkan, KRISTOFFERSSON, Ulf, EHRENCRONA, Hans, LILJEGREN, Annelie, VAN DER LUIJT, Rob B, VAN OS, Theo A, VAN LEEUWEN, Flora E, DOMCHEK, Susan M, REBBECK, Timothy R, NATHANSON, Katherine L, PEOCK, Susan, OSORIO, Ana, RAMON Y CAJAL, Teresa, KONSTANTOPOULOU, Irene, BENITEZ, Javier, FRIEDMAN, Eitan, KAUFMAN, Bella, LAITMAN, Yael, MAI, Phuong L, GREENE, Mark H, NEVANLINNA, Heli, COOK, Margaret, OLIVER, Clare, FROST, Debra, MAYES, Rebecca
Published in Cancer epidemiology, biomarkers & prevention (2010)
Published in Cancer epidemiology, biomarkers & prevention (2010)
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The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers
Laitman, Yael, Kuchenbaecker, Karoline B., Rantala, Johanna, Hogervorst, Frans, Peock, Susan, Godwin, Andrew K., Arason, Adalgeir, Kirchhoff, Tomas, Offit, Kenneth, Isaacs, Claudine, Schmutzler, Rita K., Wappenschmidt, Barbara, Nevanlinna, Heli, Chen, Xiaoqing, Chenevix-Trench, Georgia, Healey, Sue, Couch, Fergus, Peterlongo, Paolo, Radice, Paolo, Nathanson, Katherine L., Caligo, Maria Adelaide, Neuhausen, Susan L., Ganz, Patricia, Sinilnikova, Olga M., McGuffog, Lesley, Easton, Douglas F., Antoniou, Antonis C., Wolf, Ido, Friedman, Eitan
Published in Breast cancer research and treatment (01.04.2012)
Published in Breast cancer research and treatment (01.04.2012)
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Evaluation of fanconi Anemia genes in familial breast cancer predisposition
SEAL, Sheila, BARFOOT, Rita, STRATTON, Michael R, RAHMAN, Nazneen, JAYATILAKE, Hiran, SMITH, Paula, RENWICK, Anthony, BASCOMBE, Linda, MCGUFFOG, Lesley, EVANS, D. Gareth, ECCLES, Diana, EASTON, Douglas F
Published in Cancer research (Chicago, Ill.) (15.12.2003)
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Published in Cancer research (Chicago, Ill.) (15.12.2003)
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Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2
Osorio, A, Milne, R L, Alonso, R, Pita, G, Peterlongo, P, Teulé, A, Nathanson, K L, Domchek, S M, Rebbeck, T, Lasa, A, Konstantopoulou, I, Hogervorst, F B, Verhoef, S, van Dooren, M F, Jager, A, Ausems, M G E M, Aalfs, C M, van Asperen, C J, Vreeswijk, M, Waisfisz, Q, Van Roozendaal, C E, Ligtenberg, M J, Easton, D F, Peock, S, Cook, M, Oliver, C T, Frost, D, Curzon, B, Evans, D G, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Adlard, J, Eccles, D, Ong, K-r, Douglas, F, Downing, S, Brewer, C, Walker, L, Nevanlinna, H, Aittomäki, K, Couch, F J, Fredericksen, Z, Lindor, N M, Godwin, A, Isaacs, C, Caligo, M A, Loman, N, Jernström, H, Barbany-Bustinza, G, Liljegren, A, Ehrencrona, H, Stenmark-Askmalm, M, Feliubadaló, L, Manoukian, S, Peissel, B, Zaffaroni, D, Bonanni, B, Fortuzzi, S, Johannsson, O T, Chenevix-Trench, G, Chen, X-C, Beesley, J, Spurdle, A B, Sinilnikova, O M, Healey, S, McGuffog, L, Antoniou, A C, Brunet, J, Radice, P, Benítez, J
Published in British journal of cancer (12.04.2011)
Published in British journal of cancer (12.04.2011)
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Journal Article
Association of PHB 1630 C > T and MTHFR 677 C > T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study
Jakubowska, A., Rozkrut, D., Antoniou, A., Hamann, U., Scott, R. J., McGuffog, L., Sinilnikova, O. M., Rennert, G., Lejbkowicz, F., Flugelman, A., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Kantala, J., Aroer, B., Von Wachenfeldt, A., Liljegren, A., Loman, N., Kristoffersson, U., Rosenquist, R., Karlsson, P., Stenmark-Askmalm, M., Nathanson, K. L., Domchek, S. M., Byrski, T., Gronwald, J., Cybulski, C., Serrano, P., Osorio, A., Cajal, T. R., Tsitlaidou, M., Benitez, J., Gilbert, M., Rookus, M., Aalfs, C. M., Kluijt, I., Boessenkool-Pape, J. L., Oosterwijk, J. C., van Asperen, C. J., Blok, M. J., Nelen, M. R., van den Ouweland, A. M. W., van der Luijt, R. B., Devilee, P., Easton, D. F., Peock, S., Frost, D., Platte, R., Ellis, S. D., Fineberg, E., Evans, D. G., Lalloo, F., Eeles, R., Jacobs, C., Cole, T., Cook, J., Godwin, A., Bove, B., Stoppa-Lyonnet, D., Caux-Moncoutier, V., Belotti, M., Tirapo, C., Mazoyer, S., Barjhoux, L., Boutry-Kryza, N., Pujol, P., Vennin, P., Muller, D., Fricker, J-P, Venat-Bouvet, L., Johannsson, OTh, Isaacs, C., Schmutzler, R., Wappenschmidt, B., Meindl, A., Arnold, N., Varon-Mateeva, R., Niederacher, D., Sutter, C., Deissler, H., Preisler-Adams, S., Simard, J., Soucy, P., Durocher, F., Chenevix-Trench, G., Beesley, J., Chen, X., Rebbeck, T., Couch, F., Wang, X., Lindor, N., Pankratz, V. S., Peterlongo, P., Bonanni, B., Fortuzzi, S., Peissel, B., Mai, P. L., Loud, J. T., Lubinski, J.
Published in British journal of cancer (2012)
Published in British journal of cancer (2012)
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Journal Article
No evidence that GATA3 rs570613 SNP modifies breast cancer risk
Johnatty, Sharon E, Couch, Fergus J, Fredericksen, Zachary, Tarrell, Robert, Spurdle, Amanda B, Beesley, Jonathan, Chen, Xiaoqing, Gschwantler-Kaulich, Daphne, Singer, Christian F, Fuerhauser, Christine, Fink-Retter, Anneliese, Domchek, Susan M, Nathanson, Katherine L, Pankratz, Vernon S, Lindor, Noralane M, Godwin, Andrew K, Caligo, Maria A, Hopper, John, Southey, Melissa C, Giles, Graham G, Justenhoven, Christina, Brauch, Hiltrud, Hamann, Ute, Ko, Yon-Dschun, Heikkinen, Tuomas, Aaltonen, Kirsimari, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli, Hall, Per, Czene, Kamila, Liu, Jianjun, Peock, Susan, Cook, Margaret, Platte, Radka, Gareth Evans, D, Lalloo, Fiona, Eeles, Rosalind, Pichert, Gabriella, Eccles, Diana, Davidson, Rosemarie, Cole, Trevor, Cook, Jackie, Douglas, Fiona, Chu, Carol, Hodgson, Shirley, Paterson, Joan, Hogervorst, Frans B. L, Rookus, Matti A, Seynaeve, Caroline, Wijnen, Juul, Vreeswijk, Maaike, Ligtenberg, Marjolijn, van der Luijt, Rob B, van Os, Theo A. M, Gille, Hans J. P, Blok, Marinus J, Issacs, Claudine, Humphreys, Manjeet K, McGuffog, Lesley, Healey, Sue, Sinilnikova, Olga, Antoniou, Antonis C, Easton, Douglas F, Chenevix-Trench, Georgia
Published in Breast cancer research and treatment (01.09.2009)
Published in Breast cancer research and treatment (01.09.2009)
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Journal Article
An evaluation of the polymorphisms Ins 16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCAI and BRCA2 mutation carriers
OSORIO, A, POLLAN, M, HOFMANN, W, GADZICKI, D, JAKUBOWSKA, A, HAMANN, U, LUBINSKI, J, TOLOCZKO-GRABAREK, A, CYBULSKI, C, DEBNIAK, T, LIORT, G, YANNOUKAKOS, D, PITA, G, DIEZ, O, PEISSEL, B, PETERLONGO, P, RADICE, P, HEIKKINEN, T, NEVANLINNA, H, MAI, P. L, LOUD, J. T, MCGUFFOG, L, ANTONIOU, A. C, SCHMUTZLER, R. K, BENITEZ, J, VERSMOLD, B, ENGEL, C, MEINDL, A, ARNOLD, N, PREISLER-ADAMS, S, NIEDERACHER, D
Published in British journal of cancer (2008)
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Published in British journal of cancer (2008)
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