Expanding the Scope of Electrophiles Capable of Targeting K‑Ras Oncogenes
McGregor, Lynn M, Jenkins, Meredith L, Kerwin, Caitlin, Burke, John E, Shokat, Kevan M
Published in Biochemistry (Easton) (27.06.2017)
Published in Biochemistry (Easton) (27.06.2017)
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An aptamer-functionalized chemomechanically modulated biomolecule catch-and-release system
Shastri, Ankita, McGregor, Lynn M., Liu, Ya, Harris, Valerie, Nan, Hanqing, Mujica, Maritza, Vasquez, Yolanda, Bhattacharya, Amitabh, Ma, Yongting, Aizenberg, Michael, Kuksenok, Olga, Balazs, Anna C., Aizenberg, Joanna, He, Ximin
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A DNA-based molecular probe for optically reporting cellular traction forces
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Published in Nature methods (01.12.2014)
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Interaction-Dependent PCR: Identification of Ligand−Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase Experiment
McGregor, Lynn M, Gorin, David J, Dumelin, Christoph E, Liu, David R
Published in Journal of the American Chemical Society (10.11.2010)
Published in Journal of the American Chemical Society (10.11.2010)
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Correction to “Rational Chemical Design of Molecular Glue Degraders”
Toriki, Ethan S., Papatzimas, James W., Nishikawa, Kaila, Dovala, Dustin, Frank, Andreas O., Hesse, Matthew J., Dankova, Daniela, Song, Jae-Geun, Bruce-Smythe, Megan, Struble, Heidi, Garcia, Francisco J., Brittain, Scott M., Kile, Andrew C., McGregor, Lynn M., McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Published in ACS central science (23.08.2023)
Published in ACS central science (23.08.2023)
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Manumycin polyketides act as molecular glues between UBR7 and P53
Isobe, Yosuke, Okumura, Mikiko, McGregor, Lynn M., Brittain, Scott M., Jones, Michael D., Liang, Xiaoyou, White, Ross, Forrester, William, McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Published in Nature chemical biology (01.11.2020)
Published in Nature chemical biology (01.11.2020)
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Deubiquitinase-targeting chimeras for targeted protein stabilization
Henning, Nathaniel J., Boike, Lydia, Spradlin, Jessica N., Ward, Carl C., Liu, Gang, Zhang, Erika, Belcher, Bridget P., Brittain, Scott M., Hesse, Matthew J., Dovala, Dustin, McGregor, Lynn M., Valdez Misiolek, Rachel, Plasschaert, Lindsey W., Rowlands, David J., Wang, Feng, Frank, Andreas O., Fuller, Daniel, Estes, Abigail R., Randal, Katelyn L., Panidapu, Anoohya, McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Published in Nature chemical biology (01.04.2022)
Published in Nature chemical biology (01.04.2022)
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Novel selection methods for DNA-encoded chemical libraries
Chan, Alix I, McGregor, Lynn M, Liu, David R
Published in Current opinion in chemical biology (01.06.2015)
Published in Current opinion in chemical biology (01.06.2015)
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A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL
Tong, Bingqi, Spradlin, Jessica N, Novaes, Luiz F. T, Zhang, Erika, Hu, Xirui, Moeller, Malte, Brittain, Scott M, McGregor, Lynn M, McKenna, Jeffrey M, Tallarico, John A, Schirle, Markus, Maimone, Thomas J, Nomura, Daniel K
Published in ACS chemical biology (17.07.2020)
Published in ACS chemical biology (17.07.2020)
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An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4
Gonzalez-Valero, Angel, Reeves, Audrey G., Page, Annika C. S., Moon, Patrick J., Miller, Edward, Coulonval, Katia, Crossley, Steven W. M., Xie, Xiao, He, Dan, Musacchio, Patricia Z., Christian, Alec H., McKenna, Jeffrey M., Lewis, Richard A., Fang, Eric, Dovala, Dustin, Lu, Yipin, McGregor, Lynn M., Schirle, Markus, Tallarico, John A., Roger, Pierre P., Toste, F. Dean, Chang, Christopher J.
Published in Journal of the American Chemical Society (21.12.2022)
Published in Journal of the American Chemical Society (21.12.2022)
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A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
Pinch, Benika J., Buckley, Dennis L., Gleim, Scott, Brittain, Scott M., Tandeske, Laura, D'Alessandro, Pier Luca, Hauseman, Zachary J., Lipps, Jennifer, Xu, Lei, Harvey, Edward P., Schirle, Markus, Sprague, Elizabeth R., Forrester, William C., Dovala, Dustin, McGregor, Lynn M., Thoma, Claudio R.
Published in Cell chemical biology (20.01.2022)
Published in Cell chemical biology (20.01.2022)
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Rational Chemical Design of Molecular Glue Degraders
Toriki, Ethan S., Papatzimas, James W., Nishikawa, Kaila, Dovala, Dustin, Frank, Andreas O., Hesse, Matthew J., Dankova, Daniela, Song, Jae-Geun, Bruce-Smythe, Megan, Struble, Heidi, Garcia, Francisco J., Brittain, Scott M., Kile, Andrew C., McGregor, Lynn M., McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Published in ACS central science (24.05.2023)
Published in ACS central science (24.05.2023)
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Manumycin Polyketides Act as Molecular Glues Between UBR7 and P53 to Impair Breast Cancer Pathogenicity
Isobe, Yosuke, Okumura, Mikiko, White, Ross, Mcgregor, Lynn M, Mckenna, Jeffrey M, Tallarico, John A, Schirle, Markus, Maimone, Thomas J, Nomura, Daniel K
Published in bioRxiv (22.10.2019)
Published in bioRxiv (22.10.2019)
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A Strategy to Assess the Cellular Activity of E3 Ligases against Neo-Substrates using Electrophilic Probes
Pinch, Benika J, Buckley, Dennis L, Gleim, Scott, Brittain, Scott M, Tandeske, Laura, D'alessandro, Pier Luca, Harvey, Edward P, Hauseman, Zachary J, Schirle, Markus, Sprague, Elizabeth R, rester, William C, Dovala, Dustin, Mcgregor, Lynn M, Thoma, Claudio R
Published in bioRxiv (16.08.2020)
Published in bioRxiv (16.08.2020)
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