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McGregor, Grace H, Campbell, Andrew D, Fey, Sigrid K, Tumanov, Sergey, Sumpton, David, Blanco, Giovanny Rodriguez, Mackay, Gillian, Nixon, Colin, Vazquez, Alexei, Sansom, Owen J, Kamphorst, Jurre J
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Published in Cancer research (Chicago, Ill.) (15.01.2020)
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2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
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Published in Nature communications (19.05.2020)
Published in Nature communications (19.05.2020)
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Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress
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Published in Cancer research (Chicago, Ill.) (15.01.2020)
Published in Cancer research (Chicago, Ill.) (15.01.2020)
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Insulin-regulated serine and lipid metabolism drive peripheral neuropathy
Handzlik, Michal K., Gengatharan, Jivani M., Frizzi, Katie E., McGregor, Grace H., Martino, Cameron, Rahman, Gibraan, Gonzalez, Antonio, Moreno, Ana M., Green, Courtney R., Guernsey, Lucie S., Lin, Terry, Tseng, Patrick, Ideguchi, Yoichiro, Fallon, Regis J., Chaix, Amandine, Panda, Satchidananda, Mali, Prashant, Wallace, Martina, Knight, Rob, Gantner, Marin L., Calcutt, Nigel A., Metallo, Christian M.
Published in Nature (London) (02.02.2023)
Published in Nature (London) (02.02.2023)
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1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells
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Published in Journal of lipid research (01.10.2022)
Published in Journal of lipid research (01.10.2022)
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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer
Blomme, Arnaud, Peter, Coralie, Mui, Ernest, Rodriguez Blanco, Giovanny, An, Ning, Mason, Louise M, Jamieson, Lauren E, McGregor, Grace H, Lilla, Sergio, Ntala, Chara, Patel, Rachana, Thiry, Marc, Kung, Sonia H Y, Leclercq, Marine, Ford, Catriona A, Rushworth, Linda K, McGarry, David J, Mason, Susan, Repiscak, Peter, Nixon, Colin, Salji, Mark J, Markert, Elke, MacKay, Gillian M, Kamphorst, Jurre J, Graham, Duncan, Faulds, Karen, Fazli, Ladan, Gleave, Martin E, Avezov, Edward, Edwards, Joanne, Yin, Huabing, Sumpton, David, Blyth, Karen, Close, Pierre, Murphy, Daniel J, Zanivan, Sara, Leung, Hing Y
Published in EMBO molecular medicine (07.03.2022)
Published in EMBO molecular medicine (07.03.2022)
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Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Kay, Emily J., Paterson, Karla, Riera-Domingo, Carla, Sumpton, David, Däbritz, J. Henry M., Tardito, Saverio, Boldrini, Claudia, Hernandez-Fernaud, Juan R., Athineos, Dimitris, Dhayade, Sandeep, Stepanova, Ekaterina, Gjerga, Enio, Neilson, Lisa J., Lilla, Sergio, Hedley, Ann, Koulouras, Grigorios, McGregor, Grace, Jamieson, Craig, Johnson, Radia Marie, Park, Morag, Kirschner, Kristina, Miller, Crispin, Kamphorst, Jurre J., Loayza-Puch, Fabricio, Saez-Rodriguez, Julio, Mazzone, Massimiliano, Blyth, Karen, Zagnoni, Michele, Zanivan, Sara
Published in Nature metabolism (01.06.2022)
Published in Nature metabolism (01.06.2022)
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Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease
Green, Courtney R., Bonelli, Roberto, Ansell, Brendan R.E., Tzaridis, Simone, Handzlik, Michal K., McGregor, Grace H., Hart, Barbara, Trombley, Jennifer, Reilly, Mary M., Bernstein, Paul S., Egan, Catherine, Fruttiger, Marcus, Wallace, Martina, Bahlo, Melanie, Friedlander, Martin, Metallo, Christian M., Gantner, Marin L.
Published in Molecular metabolism (Germany) (01.06.2023)
Published in Molecular metabolism (Germany) (01.06.2023)
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Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress
Kuna, Ramya S, Kumar, Avi, Wessendorf-Rodriguez, Karl A, Galvez, Hector, Green, Courtney R, McGregor, Grace H, Cordes, Thekla, Shaw, Reuben J, Svensson, Robert U, Metallo, Christian M
Published in Science advances (03.05.2023)
Published in Science advances (03.05.2023)
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Abstract B76: Pyruvate dehydrogenase: A key to epigenetic regulation in CAFs
Kay, Emily, Neilson, Lisa, Boldrini, Claudia, Hernandez-Fernaud, Juan, Gjerga, Enio, Sumpton, David, Dhayade, Sandeep, McGregor, Grace, Koulouras, Grigorios, Kamphorst, Jurre, Blyth, Karen, Saez-Rodriguez, Julio, Mackay, Gillian, Zanivan, Sara
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Kay, Emily J., Paterson, Karla, Riera-Domingo, Carla, Sumpton, David, Däbritz, J. Henry M., Tardito, Saverio, Boldrini, Claudia, Hernandez-Fernaud, Juan R., Athineos, Dimitris, Dhayade, Sandeep, Stepanova, Ekaterina, Gjerga, Enio, Neilson, Lisa J., Lilla, Sergio, Hedley, Ann, Koulouras, Grigorios, McGregor, Grace, Jamieson, Craig, Johnson, Radia Marie, Park, Morag, Kirschner, Kristina, Miller, Crispin, Kamphorst, Jurre J., Loayza-Puch, Fabricio, Saez-Rodriguez, Julio, Mazzone, Massimiliano, Blyth, Karen, Zagnoni, Michele, Zanivan, Sara
Published in Nature metabolism (01.08.2022)
Published in Nature metabolism (01.08.2022)
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Modeling compound lipid homeostasis using stable isotope tracing
Wessendorf-Rodriguez, Karl, Ruchhoeft, Maureen L, Ashley, Ethan L, Galvez, Hector M, Murray, Christopher W, McGregor, Grace, Kambhampati, Shrikaar, Shaw, Reuben J, Metallo, Christian M
Published in bioRxiv (17.10.2024)
Published in bioRxiv (17.10.2024)
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1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells
Cordes, Thekla, Kuna, Ramya S, Mcgregor, Grace H, Khare, Sanika V, Jivani Gengatharan, Muthusamy, Thangaselvam, Metallo, Christian M
Published in bioRxiv (10.08.2022)
Published in bioRxiv (10.08.2022)
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PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
Kay, Emily J, Paterson, Karla, Domingo, Carla Riero, Sumpton, David, Daebritz, Henry, Tardito, Saverio, Boldrini, Claudia, Hernandez-Fernaud, Juan R, Athineos, Dimitris, Dhayade, Sandeep, Stepanova, Ekaterina, Gjerga, Enio, Neilson, Lisa J, Lilla, Sergio, Hedley, Ann, Koulouras, Grigorios, Mcgregor, Grace, Jamieson, Craig, Johnson, Radia M, Park, Morag, Kirschner, Kristina, Miller, Crispin, Kamphorst, Jurre, Loayza-Puch, Fabrizio, Saez-Rodriguez, Julio, Mazzone, Massimiliano, Blyth, Karen, Zagnoni, Michele, Zanivan, Sara
Published in bioRxiv (17.08.2021)
Published in bioRxiv (17.08.2021)
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THEM6-mediated lipid remodelling sustains stress resistance in cancer
Blomme, Arnaud, Coralie, Peter, Mui, Ernest, Giovanny Rodriguez Blanco, Mason, Louise M, Jamieson, Lauren E, Mcgregor, Grace H, Lilla, Sergio, Ntala, Chara, Patel, Rachana, Thiry, Marc, Kung, Sonia Hy, d, Catriona A, Rushworth, Linda K, Mcgarry, David J, Mason, Susan, Repiscak, Peter, Nixon, Colin, Salji, Mark J, Markert, Elke, Mackay, Gillian M, Kamphorst, Jurre J, Duncan, Graham, Faulds, Karen, Fazli, Ladan, Gleave, Martin E, Avezov, Edward, Edwards, Joanne, Yin, Huabing, Sumpton, David, Blyth, Karen, Close, Pierre, Murphy, Daniel J, Zanivan, Sara R, Leung, Hing Y
Published in bioRxiv (04.04.2021)
Published in bioRxiv (04.04.2021)
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