Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90
Bussenius, Joerg, Blazey, Charles M., Aay, Naing, Anand, Neel K., Arcalas, Arlyn, Baik, TaeGon, Bowles, Owen J., Buhr, Chris A., Costanzo, Simona, Curtis, Jeffrey K., DeFina, Steven C., Dubenko, Larisa, Heuer, Timothy S., Huang, Ping, Jaeger, Christopher, Joshi, Anagha, Kennedy, Abigail R., Kim, Angie I., Lara, Katherine, Lee, Jae, Li, Jonathan, Lougheed, Julie C., Ma, Sunghoon, Malek, Shiva, Manalo, Jean-Claire L., Martini, Jean-Francois, McGrath, Garth, Nicoll, Monique, Nuss, John M., Pack, Michael, Peto, Csaba J., Tsang, Tsze H., Wang, Longcheng, Womble, Scott W., Yakes, Michael, Zhang, Wentao, Rice, Kenneth D.
Published in Bioorganic & medicinal chemistry letters (01.09.2012)
Published in Bioorganic & medicinal chemistry letters (01.09.2012)
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Journal Article
High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888
Lyman, Susan K, Crawley, Suzanne C, Gong, Ruoyu, Adamkewicz, Joanne I, McGrath, Garth, Chew, Jason Y, Choi, Jennifer, Holst, Charles R, Goon, Leanne H, Detmer, Scott A, Vaclavikova, Jana, Gerritsen, Mary E, Blake, Robert A
Published in PloS one (07.03.2011)
Published in PloS one (07.03.2011)
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Journal Article
Correction: High-Content, High-Throughput Analysis of Cell Cycle Perturbations Induced by the HSP90 Inhibitor XL888
Lyman, Susan K., Crawley, Suzanne C., Gong, Ruoyu, Adamkewicz, Joanne I., McGrath, Garth, Chew, Jason Y., Choi, Jennifer, Holst, Charles R., Goon, Leanne H., Detmer, Scott A., Vaclavikova, Jana, Gerritsen, Mary E., Blake, Robert A.
Published in PloS one (21.03.2011)
Published in PloS one (21.03.2011)
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Journal Article
Abstract 3626: Establishing a robust NGS laboratory workflow and analysis pipeline for FFPE specimen RNAseq to support biopharmaceutical translational research
Mavrommatis, Konstantinos, Intagliata, Lauren, McGrath, Garth, Civello, Daniel, Cronin, Maureen
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract A43: Spatial organization of pancreatic ductal adenocarcinoma (PDAC)–associated immune cells from the Adjuvant Pancreatic Adenocarcinoma Clinical Trial (APACT) study
Reiss, David J., Lila, Thomas, Couto, Suzana, Kamalakaran, Sitharthan, Ren, Yan, Bowman, Doug, Ortiz, Amber, Wang, Maria, Drew, Clifton, Tsai, Kao-Tai, Marella, Mathieu, Fox, Brian, McGrath, Garth, Trotter, Matthew, Towfic, Fadi, Cushman, Ian, Ratushny, Alexander, Lu, Brian, Pierce, Daniel, Cassidy, Jim
Published in Cancer research (Chicago, Ill.) (15.12.2019)
Published in Cancer research (Chicago, Ill.) (15.12.2019)
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Abstract 5283: Shangri-Docs: a browser based tool for document exploration and automatic knowledge extraction from unstructured biomedical text
Mattmann, Chris, Intagliata, Lauren, Chu, Selina, McGrath, Garth, Totaro, Giuseppe, Civello, Daniel, Ballard, David, Long, Jeffrey, Doshi, Nipurn, Thapar, Shivika, Livstone, Michael, Ramirez, Paul, Cronin, Maureen
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 5282: A cloud-enabled open source data management platform supporting a federated research and development organization
Intagliata, Lauren, Chu, Selina, McGrath, Garth, Totaro, Giuseppe, Civello, Daniel, Doshi, Nipurn, Thapar, Shivika, Livstone, Michael, Mattmann, Chris, Ramirez, Paul, Cronin, Maureen
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
aph-1 and pen-2 Are Required for Notch Pathway Signaling, γ-Secretase Cleavage of βAPP, and Presenilin Protein Accumulation
Francis, Ross, McGrath, Garth, Zhang, Jianhuan, Ruddy, David A., Sym, Mary, Apfeld, Javier, Nicoll, Monique, Maxwell, Mark, Hai, Bing, Ellis, Michael C., Parks, Annette L., Xu, Wei, Li, Jinhe, Gurney, Mark, Myers, Richard L., Himes, Carol S., Hiebsch, Ronald, Ruble, Cara, Nye, Jeffrey S., Curtis, Daniel
Published in Developmental cell (01.07.2002)
Published in Developmental cell (01.07.2002)
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Abstract B269: Pharmacodynamic and correlative biomarker analyses in clinical trials of XL184, an oral, potent inhibitor of MET, VEGFR2, and RET
Müller, Thomas, DePrimo, Samuel, McGrath, Garth, Yu, Peiwen, Wu, Jianming, Goon, Levina, Lee, Michelle, de Costa, Anushka, Chu, Felix, Cancilla, Belinda, Huang, Stephen, Vysotskaia, Valentina, Li, Jonathan, Zhao, Lora, Wong, Mei
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Journal Article
aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation
Francis, Ross, McGrath, Garth, Zhang, Jianhuan, Ruddy, David A, Sym, Mary, Apfeld, Javier, Nicoll, Monique, Maxwell, Mark, Hai, Bing, Ellis, Michael C, Parks, Annette L, Xu, Wei, Li, Jinhe, Gurney, Mark, Myers, Richard L, Himes, Carol S, Hiebsch, Ronald, Ruble, Cara, Nye, Jeffrey S, Curtis, Daniel
Published in Developmental cell (01.07.2002)
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Published in Developmental cell (01.07.2002)
Journal Article
Marks as modifers of the PTEN pathway and methods of use
Costa, Michael R, McGrath, Garth Joseph, Lickteig, Kim, Heuer, Timothy S
Year of Publication 25.09.2012
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Year of Publication 25.09.2012
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