Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein
Szewczyk, Paul, Tao, Houchao, McGrath, Aaron P., Villaluz, Mark, Rees, Steven D., Lee, Sung Chang, Doshi, Rupak, Urbatsch, Ina L., Zhang, Qinghai, Chang, Geoffrey
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.2015)
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.2015)
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Journal Article
Molecular mechanism of the wake-promoting agent TAK-925
Yin, Jie, Kang, Yanyong, McGrath, Aaron P., Chapman, Karen, Sjodt, Megan, Kimura, Eiji, Okabe, Atsutoshi, Koike, Tatsuki, Miyanohana, Yuhei, Shimizu, Yuji, Rallabandi, Rameshu, Lian, Peng, Bai, Xiaochen, Flinspach, Mack, De Brabander, Jef K., Rosenbaum, Daniel M.
Published in Nature communications (25.05.2022)
Published in Nature communications (25.05.2022)
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Journal Article
Reply to: The G protein preference of orexin receptors is currently an unresolved issue
Yin, Jie, Kang, Yanyong, McGrath, Aaron P., Chapman, Karen, Sjodt, Megan, Kimura, Eiji, Okabe, Atsutoshi, Koike, Tatsuki, Miyanohana, Yuhei, Shimizu, Yuji, Rallabandi, Rameshu, Lian, Peng, Bai, Xiaochen, Flinspach, Mack, De Brabander, Jef K., Rosenbaum, Daniel M.
Published in Nature communications (01.06.2023)
Published in Nature communications (01.06.2023)
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Journal Article
Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure
Nicklisch, Sascha C T, Rees, Steven D, McGrath, Aaron P, Gökirmak, Tufan, Bonito, Lindsay T, Vermeer, Lydia M, Cregger, Cristina, Loewen, Greg, Sandin, Stuart, Chang, Geoffrey, Hamdoun, Amro
Published in Science advances (01.04.2016)
Published in Science advances (01.04.2016)
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Journal Article
Structure and Inhibition of Human Diamine Oxidase
McGrath, Aaron P, Hilmer, Kimberly M, Collyer, Charles A, Shepard, Eric M, Elmore, Bradley O, Brown, Doreen E, Dooley, David M, Guss, J. Mitchell
Published in Biochemistry (Easton) (20.10.2009)
Published in Biochemistry (Easton) (20.10.2009)
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Journal Article
zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences
Loughlin, Fionna E, Mansfield, Robyn E, Vaz, Paula M, McGrath, Aaron P, Setiyaputra, Surya, Gamsjaeger, Roland, Chen, Eva S, Morris, Brian J, Guss, J. Mitchell, Mackay, Joel P
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
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Journal Article
Structural basis of interprotein electron transfer in bacterial sulfite oxidation
McGrath, Aaron P, Laming, Elise L, Casas Garcia, G Patricia, Kvansakul, Marc, Guss, J Mitchell, Trewhella, Jill, Calmes, Benoit, Bernhardt, Paul V, Hanson, Graeme R, Kappler, Ulrike, Maher, Megan J
Published in eLife (19.12.2015)
Published in eLife (19.12.2015)
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Journal Article
The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti
Laming, Elise M., McGrath, Aaron P., Guss, J. Mitchell, Kappler, Ulrike, Maher, Megan J.
Published in Journal of inorganic biochemistry (01.10.2012)
Published in Journal of inorganic biochemistry (01.10.2012)
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Journal Article
Structure and Activity of Aspergillus nidulans Copper Amine Oxidase
McGrath, Aaron P, Mithieux, Suzanne M, Collyer, Charles A, Bakhuis, Janny G, van den Berg, Marco, Sein, Arjen, Heinz, Andrea, Schmelzer, Christian, Weiss, Anthony S, Guss, J. Mitchell
Published in Biochemistry (Easton) (28.06.2011)
Published in Biochemistry (Easton) (28.06.2011)
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Journal Article
Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating
Maity, Koustav, Heumann, John M., McGrath, Aaron P., Kopcho, Noah J., Hsu, Po-Kai, Lee, Chang-Wook, Mapes, James H., Garza, Denisse, Krishnan, Srinivasan, Morgan, Garry P., Hendargo, Kevin J., Klose, Thomas, Rees, Steven D., Medrano-Soto, Arturo, Saier, Milton H., Pin˜eros, Miguel, Komives, Elizabeth A., Schroeder, Julian I., Chang, Geoffrey, Stowell, Michael H. B.
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.2019)
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Journal Article
Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor
Doshi, Rupak, McGrath, Aaron P., Piñeros, Miguel, Szewczyk, Paul, Garza, Denisse M., Kochian, Leon V., Chang, Geoffrey
Published in Scientific reports (21.12.2017)
Published in Scientific reports (21.12.2017)
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Journal Article
Transporter-interfering chemicals inhibit P-glycoprotein of yellowfin tuna (Thunnus albacares)
Nicklisch, Sascha C.T., Pouv, Amara K., Rees, Steven D., McGrath, Aaron P., Chang, Geoffrey, Hamdoun, Amro
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.10.2021)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.10.2021)
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Journal Article
The uncharacterized gene EVE contributes to vessel element dimensions in Populus
Ribeiro, Cíntia L., Conde, Daniel, Balmant, Kelly M., Dervinis, Christopher, Johnson, Matthew G., McGrath, Aaron P., Szewczyk, Paul, Unda, Faride, Finegan, Christina A., Schmidt, Henry W., Miles, Brianna, Drost, Derek R., Novaes, Evandro, Gonzalez-Benecke, Carlos A., Peter, Gary F., Burleigh, J. Gordon, Martin, Timothy A., Mansfield, Shawn D., Chang, Geoffrey, Wicketti, Norman J., Kirst, Matias
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2020)
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Journal Article
The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells
Lovelace, Michael D, Powter, Elizabeth E, Coleman, Paul R, Zhao, Yang, Parker, Amelia, Chang, Garry H, Lay, Angelina J, Hunter, Julie, McGrath, Aaron P, Jormakka, Mika, Bertolino, Patrick, McCaughan, Geoffrey, Kavallaris, Maria, Vadas, Mathew A, Gamble, Jennifer R
Published in Molecular biology of the cell (15.04.2017)
Published in Molecular biology of the cell (15.04.2017)
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Journal Article
Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats
Petras, Daniel, Nothias, Louis-Félix, Quinn, Robert A, Alexandrov, Theodore, Bandeira, Nuno, Bouslimani, Amina, Castro-Falcón, Gabriel, Chen, Liangyu, Dang, Tam, Floros, Dimitrios J, Hook, Vivian, Garg, Neha, Hoffner, Nicole, Jiang, Yike, Kapono, Clifford A, Koester, Irina, Knight, Rob, Leber, Christopher A, Ling, Tie-Jun, Luzzatto-Knaan, Tal, McCall, Laura-Isobel, McGrath, Aaron P, Meehan, Michael J, Merritt, Jonathan K, Mills, Robert H, Morton, Jamie, Podvin, Sonia, Protsyuk, Ivan, Purdy, Trevor, Satterfield, Kendall, Searles, Stephen, Shah, Sahil, Shires, Sarah, Steffen, Dana, White, Margot, Todoric, Jelena, Tuttle, Robert, Wojnicz, Aneta, Sapp, Valerie, Vargas, Fernando, Yang, Jin, Zhang, Chao, Dorrestein, Pieter C
Published in Analytical chemistry (Washington) (15.11.2016)
Published in Analytical chemistry (Washington) (15.11.2016)
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Journal Article
The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactions
Hsiao, Ju-Chun, McGrath, Aaron P., Kielmann, Linda, Kalimuthu, Palraj, Darain, Farzana, Bernhardt, Paul V., Harmer, Jeffrey, Lee, Mihwa, Meyers, Kimberley, Maher, Megan J., Kappler, Ulrike
Published in Biochimica et biophysica acta. Bioenergetics (01.01.2018)
Published in Biochimica et biophysica acta. Bioenergetics (01.01.2018)
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Journal Article
A new crystal form of human vascular adhesion protein 1
Ernberg, Karin, McGrath, Aaron P., Peat, Thomas S., Adams, Timothy E., Xiao, Xiaowen, Pham, Tam, Newman, Janet, McDonald, Ian A., Collyer, Charles A., Guss, J. Mitchell
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.12.2010)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.12.2010)
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Journal Article
The structural basis of bacterial manganese import
Neville, Stephanie L, Sjöhamn, Jennie, Watts, Jacinta A, MacDermott-Opeskin, Hugo, Fairweather, Stephen J, Ganio, Katherine, Carey Hulyer, Alex, McGrath, Aaron P, Hayes, Andrew J, Malcolm, Tess R, Davies, Mark R, Nomura, Norimichi, Iwata, So, O'Mara, Megan L, Maher, Megan J, McDevitt, Christopher A
Published in Science advances (01.08.2021)
Published in Science advances (01.08.2021)
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Journal Article
Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer
Deshpande, Chandrika N., McGrath, Aaron P., Font, Josep, Guilfoyle, Amy P., Maher, Megan J., Jormakka, Mika
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.04.2013)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.04.2013)
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Journal Article