Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury
Farr, George W., Hall, Christopher H., Farr, Susan M., Wade, Ramon, Detzel, Joshua M., Adams, Amielia G., Buch, Jasen M., Beahm, Derek L., Flask, Christopher A., Xu, Kui, LaManna, Joseph C., McGuirk, Paul R., Boron, Walter F., Pelletier, Marc F.
Published in Neuroscience (15.04.2019)
Published in Neuroscience (15.04.2019)
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Water channel aquaporin 4 is required for T cell receptor mediated lymphocyte activation
Nicosia, Michael, Lee, Juyeun, Beavers, Ashley, Kish, Danielle, Farr, George W, McGuirk, Paul R, Pelletier, Marc F, Lathia, Justin D, Fairchild, Robert L, Valujskikh, Anna
Published in Journal of leukocyte biology (01.06.2023)
Published in Journal of leukocyte biology (01.06.2023)
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Aquaporin 4 blockade improves survival of murine heart allografts subjected to prolonged cold ischemia
Ayasoufi, Katayoun, Kohei, Naoki, Nicosia, Michael, Fan, Ran, Farr, George W., McGuirk, Paul R., Pelletier, Marc F., Fairchild, Robert L., Valujskikh, Anna
Published in American journal of transplantation (01.05.2018)
Published in American journal of transplantation (01.05.2018)
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The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest
Wallisch, Jessica S., Janesko-Feldman, Keri, Alexander, Henry, Jha, Ruchira M., Farr, George W., McGuirk, Paul R., Kline, Anthony E., Jackson, Travis C., Pelletier, Marc F., Clark, Robert S. B., Kochanek, Patrick M., Manole, Mioara D.
Published in Pediatric research (01.03.2019)
Published in Pediatric research (01.03.2019)
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New Quinolone Compounds from Pseudonocardia sp. with Selective and Potent Anti-Helicobacter pylori Activity: Taxonomy of Producing Strain, Fermentation, Isolation, Structural Elucidation and Biological Activities
DEKKER, KOEN A., INAGAKI, TAISUKE, GOOTZ, THOMAS D., HUANG, LIANG H., KOJIMA, YASUHIRO, KOHLBRENNER, WILLIAM E., MATSUNAGA, YASUE, MCGUIRK, PAUL R., NOMURA, ETSUKO, SAKAKIBARA, TATSUO, SAKEMI, SHINICHI, SUZUKI, YUMIKO, YAMAUCHI, YUJI, KOJIMA, NAKAO
Published in Journal of antibiotics (01.02.1998)
Published in Journal of antibiotics (01.02.1998)
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Water channel Aquaporin 4 is required for T cell activation
Nicosia, Michael, Beavers, Ashley, Kish, Danielle, Farr, George W, McGuirk, Paul R, Pelletier, Marc F, Fairchild, Robert L, Valujskikh, Anna
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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The role of Aquaporin-4 in T cell activation
Nicosia, Michael, Beavers, Ashley M, Farr, George W, McGuirk, Paul R, Pelletier, Marc, Valujskikh, Anna
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
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Aquaporin 4 blockade alters T cell trafficking through a novel mechanism of S1PR1 regulation
Nicosia, Michael, Fan, Ran, Miyairi, Satoshi, Farr, George W., McGuirk, Paul R., Pelletier, Marc F., Beavers, Ashley, Valujskikh, Anna
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Residue depletion studies on danofloxacin in the chicken
Lynch, Martin J, Rice, John R, Ericson, Jon F, Mosher, Franklin R, Millas, Wayne J, Harran, Lydia P, Frame, George M, Illyes, Elizabeth F, McGuirk, Paul R
Published in Journal of agricultural and food chemistry (01.02.1994)
Published in Journal of agricultural and food chemistry (01.02.1994)
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Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine
McGuirk, Paul R, Jefson, Martin R, Mann, Douglas D, Elliott, Nancy C, Chang, Polly, Cisek, Eugene P, Cornell, C. Peter, Gootz, Thomas D, Haskell, Susan L
Published in Journal of medicinal chemistry (01.02.1992)
Published in Journal of medicinal chemistry (01.02.1992)
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Assays to Detect and Characterize Synthetic Agents that Inhibit the ErmC Methyltransferase
CLANCY, JOANNA, SCHMIEDER, BRENDA J., PETITPAS, JOAN W., MANOUSOS, MARY, WILLIAMS, JOHN A., FAIELLA, JAMES A., GIRARD, ARTHUR E., MCGUIRK, PAUL R.
Published in Journal of antibiotics (1995)
Published in Journal of antibiotics (1995)
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INTERMEDIATES FOR PREPARING 1,4-DIHYDRO-4-OXO-QUINOLINE-3 CARBOXYLIC ACID ESTERS
BUSCH, FRANK R, O'NEILL, BRIAN T, McGUIRK, PAUL R, HECKER, SCOTT J, WATSON, HARRY A. JR
Year of Publication 30.01.1992
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Year of Publication 30.01.1992
Patent
Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage
Robinson, M.J. (Vanderbilt University School of Medicine, Nashville, TN), Martin, B.A, Gootz, T.D, McGuirk, P.R, Moynihan, M, Sutcliffe, J.A, Osheroff, N
Published in The Journal of biological chemistry (05.08.1991)
Published in The Journal of biological chemistry (05.08.1991)
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Analysis of eukaryotic topoisomerase II cleavage sites in the presence of the quinolone CP-115,953 reveals drug-dependent and -independent recognition elements
Spitzner, J R, Chung, I K, Gootz, T D, McGuirk, P R, Muller, M T
Published in Molecular pharmacology (01.08.1995)
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Published in Molecular pharmacology (01.08.1995)
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