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Published in PloS one (01.08.2024)
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An androgen receptor N-terminal domain antagonist for treating prostate cancer
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Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer
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Andersen, Raymond J., Mawji, Nasrin R., Wang, Jun, Wang, Gang, Haile, Simon, Myung, Jae-Kyung, Watt, Kate, Tam, Teresa, Yang, Yu Chi, Bañuelos, Carmen A., Williams, David E., McEwan, Iain J., Wang, Yuzhou, Sadar, Marianne D.
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Published in Cancer cell (15.06.2010)
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Tissue control of androgen action: The ups and downs of androgen receptor expression
Hunter, Irene, Hay, Colin W., Esswein, Bianca, Watt, Kate, McEwan, Iain J.
Published in Molecular and cellular endocrinology (15.04.2018)
Published in Molecular and cellular endocrinology (15.04.2018)
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New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity
Hwang, Dong-Jin, He, Yali, Ponnusamy, Suriyan, Mohler, Michael L, Thiyagarajan, Thirumagal, McEwan, Iain J, Narayanan, Ramesh, Miller, Duane D
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Orally Bioavailable Androgen Receptor Degrader, Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer
Ponnusamy, Suriyan, He, Yali, Hwang, Dong-Jin, Thiyagarajan, Thirumagal, Houtman, Rene, Bocharova, Vera, Sumpter, Bobby G, Fernandez, Elias, Johnson, Daniel, Du, Ziyun, Pfeffer, Lawrence M, Getzenberg, Robert H, McEwan, Iain J, Miller, Duane D, Narayanan, Ramesh
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Published in Clinical cancer research (15.11.2019)
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Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
RICHARDS, Juliet, AI CHIIN LIM, MCEWAN, Lain J, DE BONO, Johann S, ATTARD, Gerhardt, HAY, Colin W, TAYLOR, Angela E, WINGATE, Anna, NOWAKOWSKA, Karolina, PEZARO, Carmel, CARREIRA, Suzanne, GOODALL, Jane, ARLT, Wiebke
Published in Cancer research (Chicago, Ill.) (01.05.2012)
Published in Cancer research (Chicago, Ill.) (01.05.2012)
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Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
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Published in Cancer research (Chicago, Ill.) (15.11.2017)
Published in Cancer research (Chicago, Ill.) (15.11.2017)
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Topological dynamics of an intrinsically disordered N‐terminal domain of the human androgen receptor
Sheikhhassani, Vahid, Scalvini, Barbara, Ng, Julian, Heling, Laurens W. H. J., Ayache, Yosri, Evers, Tom M. J., Estébanez‐Perpiñá, Eva, McEwan, Iain J., Mashaghi, Alireza
Published in Protein science (01.06.2022)
Published in Protein science (01.06.2022)
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