An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides
Houssen, Wael E., Bent, Andrew F., McEwan, Andrew R., Pieiller, Nathalie, Tabudravu, Jioji, Koehnke, Jesko, Mann, Greg, Adaba, Rosemary I., Thomas, Louise, Hawas, Usama W., Liu, Huanting, Schwarz-Linek, Ulrich, Smith, Margaret C. M., Naismith, James H., Jaspars, Marcel
Published in Angewandte Chemie International Edition (15.12.2014)
Published in Angewandte Chemie International Edition (15.12.2014)
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Isolation and anti-HIV-1 integrase activity of lentzeosides A–F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil
Wichner, Dominik, Idris, Hamidah, Houssen, Wael E, McEwan, Andrew R, Bull, Alan T, Asenjo, Juan A, Goodfellow, Michael, Jaspars, Marcel, Ebel, Rainer, Rateb, Mostafa E
Published in Journal of antibiotics (01.04.2017)
Published in Journal of antibiotics (01.04.2017)
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Mechanism of Enzymatic Fluorination in Streptomyces cattleya
ZHU, Xiaofeng, ROBINSON, David A., MCEWAN, Andrew R., O'HAGAN, David, NAISMITH, James H.
Published in Journal of the American Chemical Society (28.11.2007)
Published in Journal of the American Chemical Society (28.11.2007)
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Gated rotation mechanism of site-specific recombination by ΦC31 integrase
Olorunniji, Femi J., Buck, Dorothy E., Colloms, Sean D., McEwan, Andrew R., Smith, Margaret C. M., Stark, W. Marshall, Rosser, Susan J.
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2012)
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The Fluorinase from Streptomyces cattleya Is Also a Chlorinase
Deng, Hai, Cobb, Steven L., McEwan, Andrew R., McGlinchey, Ryan P., Naismith, James H., O'Hagan, David, Robinson, David A., Spencer, Jonathan B.
Published in Angewandte Chemie International Edition (23.01.2006)
Published in Angewandte Chemie International Edition (23.01.2006)
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An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans
McEwan, Andrew R., Hing, Benjamin, Erickson, Johanna C., Hutchings, Greg, Urama, Charity, Norton-Hughes, Emily, D’Ippolito, Mariam, Berry, Susan, Delibegovic, Mirela, Grassmann, Felix, MacKenzie, Alasdair
Published in Molecular psychiatry (01.03.2024)
Published in Molecular psychiatry (01.03.2024)
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Disease‐associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue‐specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics
Hay, Elizabeth A., Cowie, Philip, McEwan, Andrew R., Ross, Ruth, Pertwee, Roger G., MacKenzie, Alasdair
Published in Human mutation (01.01.2020)
Published in Human mutation (01.01.2020)
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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake
McEwan, Andrew R., Davidson, Connor, Hay, Elizabeth, Turnbull, Yvonne, Erickson, Johanna Celene, Marini, Pietro, Wilson, Dana, McIntosh, Andrew M., Adams, Mark J., Murgatroyd, Chris, Barrett, Perry, Delibegovic, Mirela, Clarke, Toni-Kim, MacKenzie, Alasdair
Published in Molecular psychiatry (01.06.2021)
Published in Molecular psychiatry (01.06.2021)
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A phage protein that binds φC31 integrase to switch its directionality
Khaleel, Thanafez, Younger, Ellen, McEwan, Andrew R., Varghese, Anpu S., Smith, Margaret C. M.
Published in Molecular microbiology (01.06.2011)
Published in Molecular microbiology (01.06.2011)
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Accurate quantification of modified cyclic peptides without the need for authentic standards
Adaba, Rosemary I., Mann, Greg, Raab, Andrea, Houssen, Wael E., McEwan, Andrew R., Thomas, Louise, Tabudravu, Jioji, Naismith, James H., Jaspars, Marcel
Published in Tetrahedron (29.12.2016)
Published in Tetrahedron (29.12.2016)
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A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize
Booth, Jonathan, Alexandru-Crivac, Christina-Nicoleta, Rickaby, Kirstie A, Nneoyiegbe, Ada F, Umeobika, Ugochukwu, McEwan, Andrew R, Trembleau, Laurent, Jaspars, Marcel, Houssen, Wael E, Shalashilin, Dmitrii V
Published in The journal of physical chemistry letters (18.05.2017)
Published in The journal of physical chemistry letters (18.05.2017)
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DNA binding and synapsis by the large C-terminal domain of ϕC31 integrase
McEwan, Andrew R., Rowley, Paul A., Smith, Margaret C. M.
Published in Nucleic acids research (01.08.2009)
Published in Nucleic acids research (01.08.2009)
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Journal Article
Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrase
McEwan, Andrew R, Raab, Andrea, Kelly, Sharon M, Feldmann, Jörg, Smith, Margaret C M
Published in Nucleic acids research (01.08.2011)
Published in Nucleic acids research (01.08.2011)
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Journal Article
Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates
Cobb, Steven L, Deng, Hai, McEwan, Andrew R, Naismith, James H, O'Hagan, David, Robinson, David A
Published in Organic & biomolecular chemistry (01.01.2006)
Published in Organic & biomolecular chemistry (01.01.2006)
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Journal Article
Mechanism of Enzymatic Fluorination in Streptomyces c attleya
Zhu, Xiaofeng, Robinson, David A, McEwan, Andrew R, O'Hagan, David, Naismith, James H
Published in Journal of the American Chemical Society (28.11.2007)
Published in Journal of the American Chemical Society (28.11.2007)
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Journal Article
An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides
Houssen, Wael E., Bent, Andrew F., McEwan, Andrew R., Pieiller, Nathalie, Tabudravu, Jioji, Koehnke, Jesko, Mann, Greg, Adaba, Rosemary I., Thomas, Louise, Hawas, Usama W., Liu, Huanting, Schwarz-Linek, Ulrich, Smith, Margaret C. M., Naismith, James H., Jaspars, Marcel
Published in Angewandte Chemie (15.12.2014)
Published in Angewandte Chemie (15.12.2014)
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Journal Article
Isolation and anti-HIV-1 integrase activity of Ientzeosides A-F from extremotolerant lentzea sp H45, a strain isolated from a high-altitude Atacama Desert soil
Wichner, Dominik, Idris, Hamidah, Houssen, Wael E., McEwan, Andrew R., Bull, Alan T., Asenjo, Juan A., Goodfellow, Michael, Jasparsi, Marcel, Ebell, Rainer, Rateb, Mostafa E.
Published in Journal of antibiotics (01.04.2017)
Published in Journal of antibiotics (01.04.2017)
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Journal Article