Novel synthesis of O super(6)-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O super(6)-methylguanine DNA methyltransferase (MGMT)
Shibata, Takayuki, Glynn, Nicola, McMurry, TBrian H, McElhinney, RStanley, Margison, Geoffrey P, Williams, David M
Published in Nucleic acids research (01.01.2006)
Published in Nucleic acids research (01.01.2006)
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Lomeguatrib, a Potent Inhibitor of O super(6)-Alkylguanine-DNA-Alkyltransferase: Phase I Safety, Pharmacodynamic, and Pharmacokinetic Trial and Evaluation in Combination with Temozolomide in Patients with Advanced Solid Tumors
Ranson, Malcolm, Middleton, Mark R, Bridgewater, John, Lee, Siow Ming, Dawson, Martin, Jowle, Debra, Halbert, Gavin, Waller, Sue, McGrath, Helen, Gumbrell, Lindsey, McElhinney, RStanley, Donnelly, Dorothy, McMurry, TBrian H, Margison, Geoffrey P
Published in Clinical cancer research (01.03.2006)
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Published in Clinical cancer research (01.03.2006)
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Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O super(6)-alkylguanine-DNA alkyltransferase
Barvaux, Vincent A, Lorigan, Paul, Ranson, Malcolm, Gillum, Amanda M, Mcelhinney, RStanley, Mcmurry, TBrian H, Margison, Geoffrey P
Published in Molecular cancer therapeutics (01.10.2004)
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Published in Molecular cancer therapeutics (01.10.2004)
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