Blocking of CD27-CD70 Pathway by Anti-CD70 Antibody Ameliorates Joint Disease in Murine Collagen-Induced Arthritis
Oflazoglu, Ezogelin, Boursalian, Tamar E, Zeng, Weiping, Edwards, Ana C, Duniho, Steve, McEarchern, Julie A, Law, Che-Leung, Gerber, Hans-Peter, Grewal, Iqbal S
Published in The Journal of immunology (1950) (15.09.2009)
Published in The Journal of immunology (1950) (15.09.2009)
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Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70
MCEARCHERN, Julie A, SMITH, Leia M, GREWAL, Iqbal S, LAW, Che-Leung, MCDONAGH, Charlotte F, KLUSSMAN, Kerry, GORDON, Kristine A, MORRIS-TILDEN, Carol A, DUNIHO, Steven, RYAN, Maureen, BOURSALIAN, Tamar E, CARTER, Paul J
Published in Clinical cancer research (01.12.2008)
Published in Clinical cancer research (01.12.2008)
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CD27-CD70 interactions in the pathogenesis of Waldenström macroglobulinemia
Ho, Allen W., Hatjiharissi, Evdoxia, Ciccarelli, Bryan T., Branagan, Andrew R., Hunter, Zachary R., Leleu, Xavier, Tournilhac, Olivier, Xu, Lian, O'Connor, Kelly, Manning, Robert J., Santos, Daniel Ditzel, Chemaly, Mariana, Patterson, Christopher J., Soumerai, Jacob D., Munshi, Nikhil C., McEarchern, Julie A., Law, Che-Leung, Grewal, Iqbal S., Treon, Steven P.
Published in Blood (01.12.2008)
Published in Blood (01.12.2008)
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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
Kung Sutherland, May S., Walter, Roland B., Jeffrey, Scott C., Burke, Patrick J., Yu, Changpu, Kostner, Heather, Stone, Ivan, Ryan, Maureen C., Sussman, Django, Lyon, Robert P., Zeng, Weiping, Harrington, Kimberly H., Klussman, Kerry, Westendorf, Lori, Meyer, David, Bernstein, Irwin D., Senter, Peter D., Benjamin, Dennis R., Drachman, Jonathan G., McEarchern, Julie A.
Published in Blood (22.08.2013)
Published in Blood (22.08.2013)
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Distinct Apoptotic Signaling Characteristics of the Anti-CD40 Monoclonal Antibody Dacetuzumab and Rituximab Produce Enhanced Antitumor Activity in Non-Hodgkin Lymphoma
LEWIS, Timothy S, MCCORMICK, Renee S, EMMERTON, Kim, LAU, Jeffrey T, YU, Shang-Fan, MCEARCHERN, Julie A, GREWAL, Iqbal S, LAW, Che-Leung
Published in Clinical cancer research (15.07.2011)
Published in Clinical cancer research (15.07.2011)
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Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities
McEarchern, Julie A., Oflazoglu, Ezogelin, Francisco, Leigh, McDonagh, Charlotte F., Gordon, Kristine A., Stone, Ivan, Klussman, Kerry, Turcott, Eileen, van Rooijen, Nico, Carter, Paul, Grewal, Iqbal S., Wahl, Alan F., Law, Che-Leung
Published in Blood (01.02.2007)
Published in Blood (01.02.2007)
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Clinical Binding Properties, Internalization Kinetics, and Clinicopathologic Activity of Brentuximab Vedotin: An Antibody-Drug Conjugate for CD30-Positive Lymphoid Neoplasms
Fromm, Jonathan R, McEarchern, Julie A, Kennedy, Dana, Thomas, Anju, Shustov, Andrei R, Gopal, Ajay K
Published in Clinical lymphoma, myeloma and leukemia (01.08.2012)
Published in Clinical lymphoma, myeloma and leukemia (01.08.2012)
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Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40
LAW, Che-Leung, GORDON, Kristine A, WANT, Alan F, GREWAL, Iqbal S, COLLIER, John, KLUSSMAN, Kerry, MCEARCHERN, Julie A, CERVENY, Charles G, MIXAN, Bruce J, LEE, Wyne P, ZHONGHAU LIN, VALDEZ, Patricia
Published in Cancer research (Chicago, Ill.) (15.09.2005)
Published in Cancer research (Chicago, Ill.) (15.09.2005)
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Invasion and metastasis of a mammary tumor involves TGF‐β signaling
McEarchern, Julie A., Kobie, James J., Mack, Vivian, Wu, Rita S., Meade‐Tollin, Linda, Arteaga, Carlos L., Dumont, Nancy, Besselsen, David, Seftor, Elisabeth, Hendrix, Mary J.C., Katsanis, Emmanuel, Akporiaye, Emmanuel T.
Published in International journal of cancer (01.01.2001)
Published in International journal of cancer (01.01.2001)
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Targeting CD70 for human therapeutic use
Boursalian, Tamar E, McEarchern, Julie A, Law, Che-Leung, Grewal, Iqbal S
Published in Advances in experimental medicine and biology (2009)
Published in Advances in experimental medicine and biology (2009)
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Dendritic cells efficiently acquire and present antigen derived from lung cancer cells and induce antigen-specific T-cell responses
YALING ZHOU, MCEARCHERN, Julie A, HOWARD, Edward, PESTANO, Gary, SALGALLER, Michael L, BOSCH, Marnix L
Published in Cancer Immunology, Immunotherapy (01.07.2003)
Published in Cancer Immunology, Immunotherapy (01.07.2003)
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Invasion and metastasis of a mammary tumor involves TGF-? signaling
McEarchern, Julie A., Kobie, James J., Mack, Vivian, Wu, Rita S., Meade-Tollin, Linda, Arteaga, Carlos L., Dumont, Nancy, Besselsen, David, Seftor, Elisabeth, Hendrix, Mary J.C., Katsanis, Emmanuel, Akporiaye, Emmanuel T.
Published in International journal of cancer (01.01.2001)
Published in International journal of cancer (01.01.2001)
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Abstract 2890: Mechanistic evaluation of the anti-tumor activities of 2-fluorofucose alone and in combination with anti-idiotype vaccination
Okeley, Nicole M., Zeng, Weiping, Levengood, Matthew R., McEarchern, Julie A., Jonas, Mechthild, Duniho, Steven, Senter, Peter D., Law, Che L.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 4321: Development of pyrrolobenzodiazepine-based antibody-drug conjugates for cancer
Jeffrey, Scott C., Burke, Patrick J., Sutherland, May K., Meyer, David W., Lyon, Robert P., McEarchern, Julie A., Law, Che-Leung, Senter, Peter D.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 1284: Analysis of circulating CD70+ lymphocytes and CD70 transcript expression in a phase 1 clinical trial of the CD70-targeting antibody-drug conjugate SGN-75
Law, Che-Leung, Gordon, Kristine A., Klussman, Kerry, Whiting, Nancy C., McEarchern, Julie A.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Preclinical and Clinical Binding Properties, Internalization Kinetics, and Clinicopathological Activity of Brentuximab Vedotin (SGN-35): A Novel Antibody Drug Conjugate for Anaplastic Large Cell Lymphoma and Classical Hodgkin Lymphoma
Fromm, Jonathan R, McEarchern, Julie A., Kennedy, Dana, Anju, Thomas, Shustov, Andrei R, Gopal, Ajay K
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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SGN-CD33A: A Novel CD33-Directed Antibody-Drug Conjugate, Utilizing Pyrrolobenzodiazepine Dimers, Demonstrates Preclinical Antitumor Activity Against Multi-Drug Resistant Human AML
Sutherland, May S.K., Walter, Roland B., Jeffrey, Scott C., Burke, Patrick J., Yu, Changpu, Harrington, Kimberly H., Stone, Ivan, Ryan, Maureen C., Sussman, Django, Zeng, Weiping, Benjamin, Dennis R., Bernstein, Irwin D., Senter, Peter D., Drachman, Jonathan G., McEarchern, Julie A.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Abstract 1789: Auristatin-based antibody-drug conjugates are synergistic in combination with PI3K-AKT-mTOR pathway inhibitors in hematologic malignancies and carcinoma
Lewis, Timothy S., McCormick, Renee S., Zeng, Weiping, Miyamoto, Jamie B., Kennedy, Dana, Sievers, Eric L., McEarchern, Julie A., Law, Che-Leung
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Targeted ablation of human CD30 positive cells with an anti-CD30-MMAE antibody-drug conjugate (SGN-35) in vivo inhibits antigen-specific secondary immune responses (50.17)
Oflazoglu, Ezogelin, Zeng, Weiping, Klussman, Kerry, McEarchern, Julie A, Law, Che-Leung, Grewal, Iqbal S, Sievers, Eric L, Gerber, Hans-Peter
Published in The Journal of immunology (1950) (01.04.2009)
Published in The Journal of immunology (1950) (01.04.2009)
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