Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation
Hong, Chuan, Byrne, Noel J., Zamlynny, Beata, Tummala, Srivanya, Xiao, Li, Shipman, Jennifer M., Partridge, Andrea T., Minnick, Christina, Breslin, Michael J., Rudd, Michael T., Stachel, Shawn J., Rada, Vanessa L., Kern, Jeffrey C., Armacost, Kira A., Hollingsworth, Scott A., O’Brien, Julie A., Hall, Dawn L., McDonald, Terrence P., Strickland, Corey, Brooun, Alexei, Soisson, Stephen M., Hollenstein, Kaspar
Published in Nature communications (05.02.2021)
Published in Nature communications (05.02.2021)
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Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment
Tomaszewski, Michal R., Meng, Xiangjun, Haley, Hyking D., Harrell, Charles M., Mcdonald, Terrence P., Miller, Corin O., Smith, Sean M.
Published in Journal of lipid research (01.08.2023)
Published in Journal of lipid research (01.08.2023)
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Geospatial patterns of comorbidity prevalence among people with osteoarthritis in Alberta Canada
Liu, Xiaoxiao, Shahid, Rizwan, Patel, Alka B, McDonald, Terrence, Bertazzon, Stefania, Waters, Nigel, Seidel, Judy E, Marshall, Deborah A
Published in BMC public health (15.10.2020)
Published in BMC public health (15.10.2020)
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Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology
Stump, Craig A., Cooke, Andrew J., Bruno, Joseph, Cabalu, Tamara D., Gotter, Anthony L., Harell, C. Meacham, Kuduk, Scott D., McDonald, Terrence P., O’Brien, Julie, Renger, John J., Williams, Peter D., Winrow, Christopher J., Coleman, Paul J.
Published in Bioorganic & medicinal chemistry letters (01.12.2016)
Published in Bioorganic & medicinal chemistry letters (01.12.2016)
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Journal Article
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition
Uslaner, Jason M, Tye, Spencer J, Eddins, Donnie M, Wang, Xiaohai, Fox, Steven V, Savitz, Alan T, Binns, Jacquelyn, Cannon, Christopher E, Garson, Susan L, Yao, Lihang, Hodgson, Robert, Stevens, Joanne, Bowlby, Mark R, Tannenbaum, Pamela L, Brunner, Joseph, Mcdonald, Terrence P, Gotter, Anthony L, Kuduk, Scott D, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Published in Science translational medicine (03.04.2013)
Published in Science translational medicine (03.04.2013)
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The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold
Gotter, Anthony L, Winrow, Christopher J, Brunner, Joseph, Garson, Susan L, Fox, Steven V, Binns, Jacquelyn, Harrell, Charles M, Cui, Donghui, Yee, Ka Lai, Stiteler, Mark, Stevens, Joanne, Savitz, Alan, Tannenbaum, Pamela L, Tye, Spencer J, McDonald, Terrence, Yao, Leon, Kuduk, Scott D, Uslaner, Jason, Coleman, Paul J, Renger, John J
Published in BMC neuroscience (28.08.2013)
Published in BMC neuroscience (28.08.2013)
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Journal Article
"Navigating chaos": Urban, Rural, and Remote Patient Experiences in Accessing Healthcare with Indigenous and Non-Indigenous Perspectives of Living with Chronic Low Back Pain
Crockett, Katie, Lovo, Stacey, Irvine, Alison, Trask, Catherine, Oosman, Sarah, McKinney, Veronica, McDonald, Terrence, Sari, Nazmi, Martinez-Rueda, Rosmary, Aiyer, Harini, Carnegie, Bertha, Custer, Marie, McIntosh, Stacey, Bath, Brenna
Published in Canadian journal of pain (2024)
Published in Canadian journal of pain (2024)
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Journal Article
Healthcare Provider Perspectives on Access to Healthcare for Chronic Low Back Pain Across Urban, Rural, and Remote Settings
Crockett, Katie, Lovo, Stacey, Irvine, Alison, Trask, Catherine, Oosman, Sarah, McKinney, Veronica, McDonald, Terrence, Sari, Nazmi, Martinez-Rueda, Rosmary, Aiyer, Harini, Carnegie, Bertha, Custer, Marie, McIntosh, Stacey, Bath, Brenna
Published in Health services insights (01.01.2024)
Published in Health services insights (01.01.2024)
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Journal Article
Allosteric Modulation of Group III Metabotropic Glutamate Receptor 4: A Potential Approach to Parkinson's Disease Treatment
Marino, Michael J., Williams, David L., O'Brien, Julie A., Valenti, Ornella, McDonald, Terrence P., Clements, Michelle K., Wang, Ruiping, DiLella, Anthony G., Hess, J. Fred, Kinney, Gene G., Conn, P. Jeffrey
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
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Journal Article
Healthcare Access Challenges and Facilitators for Back Pain Across the Rural-Urban Continuum in Saskatchewan, Canada: Cross-Sectional Results From a Provincial-Wide Telephone Survey
Crockett, Katie, Lovo, Stacey, Irvine, Alison, Trask, Catherine, Oosman, Sarah, McKinney, Veronica, McDonald, Terrence, Sari, Nazmi, Carnegie, Bertha, Custer, Marie, McIntosh, Stacey, Bath, Brenna
Published in Health services insights (01.01.2023)
Published in Health services insights (01.01.2023)
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Journal Article
Experiences of Health Care Access Challenges for Back Pain Care Across the Rural-Urban Continuum in Canada: Protocol for Cross-sectional Research
Crockett, Katie, Lovo, Stacey, Irvine, Alison, Trask, Catherine, Oosman, Sarah, McKinney, Veronica, McDonald, Terrence, Sari, Nazmi, Carnegie, Bertha, Custer, Marie, McIntosh, Stacey, Bath, Brenna
Published in JMIR research protocols (19.12.2022)
Published in JMIR research protocols (19.12.2022)
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Journal Article
Design, Synthesis, and Evaluation of Novel 3,6-Diaryl-4-aminoalkoxyquinolines as Selective Agonists of Somatostatin Receptor Subtype 2
Wolkenberg, Scott E, Zhao, Zhijian, Thut, Catherine, Maxwell, Jill W, McDonald, Terrence P, Kinose, Fumi, Reilly, Michael, Lindsley, Craig W, Hartman, George D
Published in Journal of medicinal chemistry (14.04.2011)
Published in Journal of medicinal chemistry (14.04.2011)
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Journal Article
Identification of receptors for neuromedin U and its role in feeding
Liu, Qingyun, Howard, Andrew D, Wang, Ruiping, Pong, Sheng-Shung, Mellin, Theodore N, Strack, Alison, Guan, Xiao-Ming, Zeng, Zhizhen, Williams, David L, Feighner, Scott D, Nunes, Christian N, Murphy, Beth, Stair, Judith N, Yu, Hong, Jiang, Qingping, Clements, Michelle K, Tan, Carina P, McKee, Karen K, Hreniuk, Donna L, McDonald, Terrence P, Lynch, Kevin R, Evans, Jilly F, Austin, Christopher P, Caskey, C. Thomas, Van der Ploeg, Lex H. T
Published in Nature (London) (06.07.2000)
Published in Nature (London) (06.07.2000)
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Journal Article
Identification and Characterization of a Second Melanin-Concentrating Hormone Receptor, MCH-2R
Sailer, Andreas W., Sano, Hideki, Zeng, Zhizhen, McDonald, Terrence P., Pan, Jie, Pong, Sheng-Shung, Feighner, Scott D., Tan, Carina P., Fukami, Takehiro, Iwaasa, Hisashi, Hreniuk, Donna L., Morin, Nancy R., Sadowski, Sharon J., Ito, Makoto, Ito, Masahiko, Bansal, Alka, Ky, Betty, Figueroa, David J., Jiang, Qingping, Austin, Christopher P., MacNeil, Douglas J., Ishihara, Akane, Ihara, Masaki, Kanatani, Akio, Lex H. T. Van der Ploeg, Howard, Andrew D., Liu, Qingyun
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2001)
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Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators
Ramirez, Andres D, Gotter, Anthony L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Tye, Spencer J, McDonald, Terrence, Brunner, Joseph, Garson, Susan L, Reiss, Duane R, Kuduk, Scott D, Coleman, Paul J, Uslaner, Jason M, Hodgson, Robert, Browne, Susan E, Renger, John J, Winrow, Christopher J
Published in Frontiers in neuroscience (01.01.2013)
Published in Frontiers in neuroscience (01.01.2013)
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Journal Article
Differential sleep-promoting effects of dual orexin receptor antagonists and GABAAreceptor modulators
Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Published in BMC neuroscience (22.09.2014)
Published in BMC neuroscience (22.09.2014)
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Discovery of 3-Substituted Aminocyclopentanes as Potent and Orally Bioavailable NR2B Subtype-Selective NMDA Antagonists
Layton, Mark E., Kelly, Michael J., Rodzinak, Kevin J., Sanderson, Philip E., Young, Steven D., Bednar, Rodney A., DiLella, Anthony G., Mcdonald, Terrence P., Wang, Hao, Mosser, Scott D., Fay, John F., Cunningham, Michael E., Reiss, Duane R., Fandozzi, Christine, Trainor, Nicole, Liang, Annie, Lis, Edward V., Seabrook, Guy R., Urban, Mark O., Yergey, James, Koblan, Kenneth S.
Published in ACS chemical neuroscience (20.07.2011)
Published in ACS chemical neuroscience (20.07.2011)
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Identification and Characterization of Novel Mammalian Neuropeptide FF-like Peptides That Attenuate Morphine-induced Antinociception
Liu, Qingyun, Guan, Xiao-Ming, Martin, William J., McDonald, Terrence P., Clements, Michelle K., Jiang, Qingping, Zeng, Zhizhen, Jacobson, Marlene, Williams, David L., Yu, Hong, Bomford, Douglas, Figueroa, David, Mallee, John, Wang, Ruiping, Evans, Jilly, Gould, Robert, Austin, Christopher P.
Published in The Journal of biological chemistry (05.10.2001)
Published in The Journal of biological chemistry (05.10.2001)
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Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABAA Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats
FOX, Steven V, GOTTER, Anthony L, LIHANG YAO, BOWLBY, Mark R, KUDUK, Scott D, COLEMAN, Paul J, HARGREAVES, Richard, WINROW, Christopher J, RENGER, John J, TYE, Spencer J, GARSON, Susan L, SAVITZ, Alan T, USLANER, Jason M, BRUNNER, Joseph I, TANNENBAUM, Pamela L, MCDONALD, Terrence P, HODGSON, Robert
Published in Neuropsychopharmacology (New York, N.Y.) (01.11.2013)
Published in Neuropsychopharmacology (New York, N.Y.) (01.11.2013)
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