Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon
Baker, Ann-Marie, Cereser, Biancastella, Melton, Samuel, Fletcher, Alexander G., Rodriguez-Justo, Manuel, Tadrous, Paul J., Humphries, Adam, Elia, George, McDonald, Stuart A.C., Wright, Nicholas A., Simons, Benjamin D., Jansen, Marnix, Graham, Trevor A.
Published in Cell reports (Cambridge) (21.08.2014)
Published in Cell reports (Cambridge) (21.08.2014)
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Journal Article
Clonality, founder mutations, and field cancerization in human ulcerative colitis-associated neoplasia
Leedham, Simon J, Graham, Trevor A, Oukrif, Dahmane, McDonald, Stuart A C, Rodriguez-Justo, Manuel, Harrison, Rebecca F, Shepherd, Neil A, Novelli, Marco R, Jankowski, Janusz A Z, Wright, Nicholas A
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2009)
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Journal Article
Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells
McDonald, Stuart A C, Greaves, Laura C, Gutierrez-Gonzalez, Lydia, Rodriguez-Justo, Manuel, Deheragoda, Maesha, Leedham, Simon J, Taylor, Robert W, Lee, Chung Yin, Preston, Sean L, Lovell, Matthew, Hunt, Toby, Elia, George, Oukrif, Dahmane, Harrison, Rebecca, Novelli, Marco R, Mitchell, Ian, Stoker, David L, Turnbull, Douglass M, Jankowski, Janusz A Z, Wright, Nicholas A
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2008)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2008)
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Journal Article
Identification of Lineage-Uncommitted, Long-Lived, Label-Retaining Cells in Healthy Human Esophagus and Stomach, and in Metaplastic Esophagus
Pan, Qiuwei, Nicholson, Anna M, Barr, Hugh, Harrison, Lea–Anne, Wilson, George D, Burkert, Julia, Jeffery, Rosemary, Alison, Malcolm R, Looijenga, Leendert, Lin, Wey–Ran, McDonald, Stuart A.C, Wright, Nicholas A, Harrison, Rebecca, Peppelenbosch, Maikel P, Jankowski, Janusz A
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2013)
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Journal Article
Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas
Thirlwell, Christina, Will, Olivia C C, Domingo, E, Graham, Trevor A, McDonald, Stuart A C, Oukrif, Dahmane, Jeffrey, Rosemary, Gorman, Maggie, Rodriguez-Justo, Manuel, Chin-Aleong, Joanne, Clark, Sue K, Novelli, Marco R, Jankowski, Janusz A, Wright, Nicholas A, Tomlinson, Ian P M, Leedham, Simon J
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2010)
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Journal Article
The Clonal Origins of Dysplasia From Intestinal Metaplasia in the Human Stomach
Gutierrez–Gonzalez, Lydia, Graham, Trevor A, Rodriguez–Justo, Manuel, Leedham, Simon J, Novelli, Marco R, Gay, Laura J, Ventayol–Garcia, Tania, Green, Alicia, Mitchell, Ian, Stoker, David L, Preston, Sean L, Bamba, Shigeki, Yamada, Eiji, Kishi, Yuuki, Harrison, Rebecca, Jankowski, Janusz A, Wright, Nicholas A, McDonald, Stuart A.C
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2011)
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Journal Article
Use of Methylation Patterns to Determine Expansion of Stem Cell Clones in Human Colon Tissue
Graham, Trevor A, Humphries, Adam, Sanders, Theodore, Rodriguez–Justo, Manuel, Tadrous, Paul J, Preston, Sean L, Novelli, Marco R, Leedham, Simon J, McDonald, Stuart A.C, Wright, Nicholas A
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2011)
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Journal Article
Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis
Galandiuk, Susan, Rodriguez–Justo, Manuel, Jeffery, Rosemary, Nicholson, Anna M, Cheng, Yong, Oukrif, Dahmane, Elia, George, Leedham, Simon J, McDonald, Stuart A.C, Wright, Nicholas A, Graham, Trevor A
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2012)
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Journal Article
Locating the stem cell niche and tracing hepatocyte lineages in human liver
Fellous, Tariq G., Islam, Shahriar, Tadrous, Paul J., Elia, George, Kocher, Hemant M., Bhattacharya, Satyajit, Mears, Lisa, Turnbull, Douglas M., Taylor, Robert W., Greaves, Laura C., Chinnery, Patrick F., Taylor, Geoffery, McDonald, Stuart A.C., Wright, Nicholas A., Alison, Malcolm R.
Published in Hepatology (Baltimore, Md.) (01.05.2009)
Published in Hepatology (Baltimore, Md.) (01.05.2009)
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Journal Article
A Methodological Approach to Tracing Cell Lineage in Human Epithelial Tissues
Fellous, Tariq G., McDonald, Stuart A.C., Burkert, Julia, Humphries, Adam, Islam, Shahriar, De‐Alwis, Nemantha M.W., Gutierrez‐Gonzalez, Lydia, Tadrous, Paul J., Elia, George, Kocher, Hemant M., Bhattacharya, Satyajit, Mears, Lisa, El‐Bahrawy, Mona, Turnbull, Douglas M., Taylor, Robert W., Greaves, Laura C., Chinnery, Patrick F., Day, Christopher P., Wright, Nicholas A., Alison, Malcolm R.
Published in Stem cells (Dayton, Ohio) (01.06.2009)
Published in Stem cells (Dayton, Ohio) (01.06.2009)
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Journal Article
Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo
MILICIC, Anita, HARRISON, Lea-Anne, EAST, Philip, OBSZYNSKA, Jolanta, SANDERS, Scott, PIAZUELO, Elena, SHAW, Jacqui, HARRISON, Rebecca, TOMLINSON, Ian P, MCDONALD, Stuart A. C, WRIGHT, Nicholas A, JANKOWSKI, Janusz A. Z, GOODLAD, Robert A, HARDY, Robert G, NICHOLSON, Anna M, PRESZ, Michal, SIEBER, Oliver, SANTANDER, Sonia, PRINGLE, James H, MANDIR, Nikki
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Journal Article
The Barrett’s Gland in Phenotype Space
McDonald, Stuart A.C, Graham, Trevor A, Lavery, Danielle L, Wright, Nicholas A, Jansen, Marnix
Published in Cellular and molecular gastroenterology and hepatology (01.01.2015)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2015)
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Journal Article
Clonal Expansion in the Human Gut: Mitochondrial DNA Mutations Show Us the Way
McDonald, Stuart A.C., Preston, Sean L., Greaves, Laura C., Leedham, Simon J., Lovell, Matthew A., Jankowski, Janusz A.Z, Turnbull, Douglass M., Wright, Nicholas A.
Published in Cell cycle (Georgetown, Tex.) (15.04.2006)
Published in Cell cycle (Georgetown, Tex.) (15.04.2006)
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Journal Article
Cell Competition in Carcinogenesis
Madan, Esha, Palma, António M, Vudatha, Vignesh, Trevino, Jose G, Natarajan, Kedar Nath, Winn, Robert A, Won, Kyoung Jae, Graham, Trevor A, Drapkin, Ronny, McDonald, Stuart A C, Fisher, Paul B, Gogna, Rajan
Published in Cancer research (Chicago, Ill.) (16.12.2022)
Published in Cancer research (Chicago, Ill.) (16.12.2022)
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Journal Article
Evolutionary history of human colitis-associated colorectal cancer
Baker, Ann-Marie, Cross, William, Curtius, Kit, Al Bakir, Ibrahim, Choi, Chang-Ho Ryan, Davis, Hayley Louise, Temko, Daniel, Biswas, Sujata, Martinez, Pierre, Williams, Marc J, Lindsay, James O, Feakins, Roger, Vega, Roser, Hayes, Stephen J, Tomlinson, Ian P M, McDonald, Stuart A C, Moorghen, Morgan, Silver, Andrew, East, James E, Wright, Nicholas A, Wang, Lai Mun, Rodriguez-Justo, Manuel, Jansen, Marnix, Hart, Ailsa L, Leedham, Simon J, Graham, Trevor A
Published in Gut (01.06.2019)
Published in Gut (01.06.2019)
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Journal Article
Crypt fusion as a homeostatic mechanism in the human colon
Baker, Ann-Marie, Gabbutt, Calum, Williams, Marc J, Cereser, Biancastella, Jawad, Noor, Rodriguez-Justo, Manuel, Jansen, Marnix, Barnes, Chris P, Simons, Benjamin D, McDonald, Stuart AC, Graham, Trevor A, Wright, Nicholas A
Published in Gut (01.11.2019)
Published in Gut (01.11.2019)
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Journal Article
Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver
Passman, Adam M., Haughey, Magnus J., Carlotti, Emanuela, Williams, Marc J., Cereser, Bianca, Lin, Meng-Lay, Devkumar, Shruthi, Gabriel, Jonathan P., Gringeri, Enrico, Cillo, Umberto, Russo, Francesco Paolo, Hoare, Matthew, ChinAleong, Joanne, Jansen, Marnix, Wright, Nicholas A., Kocher, Hermant M., Huang, Weini, Alison, Malcolm R., McDonald, Stuart A.C.
Published in Journal of hepatology (01.08.2023)
Published in Journal of hepatology (01.08.2023)
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Journal Article
Evolutionary dynamics in Barrett oesophagus: implications for surveillance, risk stratification and therapy
Schmidt, Melissa, Hackett, Richard J., Baker, Ann-Marie, McDonald, Stuart A. C., Quante, Michael, Graham, Trevor A.
Published in Nature reviews. Gastroenterology & hepatology (01.02.2022)
Published in Nature reviews. Gastroenterology & hepatology (01.02.2022)
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Journal Article
Clonal Transitions and Phenotypic Evolution in Barrett’s Esophagus
Evans, James A., Carlotti, Emanuela, Lin, Meng-Lay, Hackett, Richard J., Haughey, Magnus J., Passman, Adam M., Dunn, Lorna, Elia, George, Porter, Ross J., McLean, Mairi H., Hughes, Frances, ChinAleong, Joanne, Woodland, Philip, Preston, Sean L., Griffin, S. Michael, Lovat, Laurence, Rodriguez-Justo, Manuel, Huang, Weini, Wright, Nicholas A., Jansen, Marnix, McDonald, Stuart A.C.
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2022)
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Journal Article