The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma
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Published in Clinical therapeutics (01.04.2015)
Published in Clinical therapeutics (01.04.2015)
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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
Herbst, Roy S, Soria, Jean-Charles, Kowanetz, Marcin, Fine, Gregg D, Hamid, Omid, Gordon, Michael S, Sosman, Jeffery A, McDermott, David F, Powderly, John D, Gettinger, Scott N, Kohrt, Holbrook E K, Horn, Leora, Lawrence, Donald P, Rost, Sandra, Leabman, Maya, Xiao, Yuanyuan, Mokatrin, Ahmad, Koeppen, Hartmut, Hegde, Priti S, Mellman, Ira, Chen, Daniel S, Hodi, F Stephen
Published in Nature (London) (27.11.2014)
Published in Nature (London) (27.11.2014)
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Atezolizumab, an Anti-Programmed Death-Ligand 1 Antibody, in Metastatic Renal Cell Carcinoma: Long-Term Safety, Clinical Activity, and Immune Correlates From a Phase Ia Study
McDermott, David F, Sosman, Jeffrey A, Sznol, Mario, Massard, Christophe, Gordon, Michael S, Hamid, Omid, Powderly, John D, Infante, Jeffrey R, Fassò, Marcella, Wang, Yan V, Zou, Wei, Hegde, Priti S, Fine, Gregg D, Powles, Thomas
Published in Journal of clinical oncology (10.03.2016)
Published in Journal of clinical oncology (10.03.2016)
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Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma
Wallin, Jeffrey J, Bendell, Johanna C, Funke, Roel, Sznol, Mario, Korski, Konstanty, Jones, Suzanne, Hernandez, Genevive, Mier, James, He, Xian, Hodi, F Stephen, Denker, Mitchell, Leveque, Vincent, Cañamero, Marta, Babitski, Galina, Koeppen, Hartmut, Ziai, James, Sharma, Neeraj, Gaire, Fabien, Chen, Daniel S, Waterkamp, Daniel, Hegde, Priti S, McDermott, David F
Published in Nature communications (30.08.2016)
Published in Nature communications (30.08.2016)
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Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial
Motzer, Robert J, Rini, Brian I, McDermott, David F, Redman, Bruce G, Kuzel, Timothy M, Harrison, Michael R, Vaishampayan, Ulka N, Drabkin, Harry A, George, Saby, Logan, Theodore F, Margolin, Kim A, Plimack, Elizabeth R, Lambert, Alexandre M, Waxman, Ian M, Hammers, Hans J
Published in Journal of clinical oncology (01.05.2015)
Published in Journal of clinical oncology (01.05.2015)
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Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
Hodi, F Stephen, Dr, Chesney, Jason, Prof, Pavlick, Anna C, MD, Robert, Caroline, Prof, Grossmann, Kenneth F, MD, McDermott, David F, MD, Linette, Gerald P, MD, Meyer, Nicolas, Prof, Giguere, Jeffrey K, MD, Agarwala, Sanjiv S, Prof, Shaheen, Montaser, MD, Ernstoff, Marc S, Prof, Minor, David R, MD, Salama, April K, MD, Taylor, Matthew H, MD, Ott, Patrick A, MD, Horak, Christine, PhD, Gagnier, Paul, MD, Jiang, Joel, PhD, Wolchok, Jedd D, Prof, Postow, Michael A, MD
Published in The lancet oncology (01.11.2016)
Published in The lancet oncology (01.11.2016)
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Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial
Choueiri, Toni K, Dr, Escudier, Bernard, MD, Powles, Thomas, Prof, Tannir, Nizar M, Prof, Mainwaring, Paul N, MD, Rini, Brian I, Prof, Hammers, Hans J, MD, Donskov, Frede, MD, Roth, Bruce J, Prof, Peltola, Katriina, MD, Lee, Jae Lyun, Prof, Heng, Daniel Y C, MD, Schmidinger, Manuela, Prof, Agarwal, Neeraj, MD, Sternberg, Cora N, Prof, McDermott, David F, MD, Aftab, Dana T, PhD, Hessel, Colin, MS, Scheffold, Christian, MD, Schwab, Gisela, MD, Hutson, Thomas E, Prof, Pal, Sumanta, MD, Motzer, Robert J, Prof
Published in The lancet oncology (01.07.2016)
Published in The lancet oncology (01.07.2016)
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Everolimus Versus Sunitinib Prospective Evaluation in Metastatic Non–Clear Cell Renal Cell Carcinoma (ESPN): A Randomized Multicenter Phase 2 Trial
Tannir, Nizar M, Jonasch, Eric, Albiges, Laurence, Altinmakas, Emre, Ng, Chaan S, Matin, Surena F, Wang, Xuemei, Qiao, Wei, Dubauskas Lim, Zita, Tamboli, Pheroze, Rao, Priya, Sircar, Kanishka, Karam, Jose A, McDermott, David F, Wood, Christopher G, Choueiri, Toni K
Published in European urology (01.05.2016)
Published in European urology (01.05.2016)
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Metabolomic adaptations and correlates of survival to immune checkpoint blockade
Li, Haoxin, Bullock, Kevin, Gurjao, Carino, Braun, David, Shukla, Sachet A, Bossé, Dominick, Lalani, Aly-Khan A, Gopal, Shuba, Jin, Chelsea, Horak, Christine, Wind-Rotolo, Megan, Signoretti, Sabina, McDermott, David F, Freeman, Gordon J, Van Allen, Eliezer M, Schreiber, Stuart L, Stephen Hodi, F, Sellers, William R, Garraway, Levi A, Clish, Clary B, Choueiri, Toni K, Giannakis, Marios
Published in Nature communications (25.09.2019)
Published in Nature communications (25.09.2019)
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CheckMate 025 Randomized Phase 3 Study: Outcomes by Key Baseline Factors and Prior Therapy for Nivolumab Versus Everolimus in Advanced Renal Cell Carcinoma
Escudier, Bernard, Sharma, Padmanee, McDermott, David F, George, Saby, Hammers, Hans J, Srinivas, Sandhya, Tykodi, Scott S, Sosman, Jeffrey A, Procopio, Giuseppe, Plimack, Elizabeth R, Castellano, Daniel, Gurney, Howard, Donskov, Frede, Peltola, Katriina, Wagstaff, John, Gauler, Thomas C, Ueda, Takeshi, Zhao, Huanyu, Waxman, Ian M, Motzer, Robert J
Published in European urology (01.12.2017)
Published in European urology (01.12.2017)
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Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
Topalian, Suzanne L, Hodi, F. Stephen, Brahmer, Julie R, Gettinger, Scott N, Smith, David C, McDermott, David F, Powderly, John D, Carvajal, Richard D, Sosman, Jeffrey A, Atkins, Michael B, Leming, Philip D, Spigel, David R, Antonia, Scott J, Horn, Leora, Drake, Charles G, Pardoll, Drew M, Chen, Lieping, Sharfman, William H, Anders, Robert A, Taube, Janis M, McMiller, Tracee L, Xu, Haiying, Korman, Alan J, Jure-Kunkel, Maria, Agrawal, Shruti, McDonald, Daniel, Kollia, Georgia D, Gupta, Ashok, Wigginton, Jon M, Sznol, Mario
Published in The New England journal of medicine (28.06.2012)
Published in The New England journal of medicine (28.06.2012)
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Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma
Choueiri, Toni K, Fishman, Mayer N, Escudier, Bernard, McDermott, David F, Drake, Charles G, Kluger, Harriet, Stadler, Walter M, Perez-Gracia, Jose Luis, McNeel, Douglas G, Curti, Brendan, Harrison, Michael R, Plimack, Elizabeth R, Appleman, Leonard, Fong, Lawrence, Albiges, Laurence, Cohen, Lewis, Young, Tina C, Chasalow, Scott D, Ross-Macdonald, Petra, Srivastava, Shivani, Jure-Kunkel, Maria, Kurland, John F, Simon, Jason S, Sznol, Mario
Published in Clinical cancer research (15.11.2016)
Published in Clinical cancer research (15.11.2016)
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Prognostic Factors for Overall Survival in Patients With Metastatic Renal Cell Carcinoma Treated With Vascular Endothelial Growth Factor–Targeted Agents: Results From a Large, Multicenter Study
HENG, Daniel Y. C, WANLING XIE, VENNER, Peter, KNOX, Jennifer J, CHI, Kim N, KOLLMANNSBERGER, Christian, MCDERMOTT, David F, OH, William K, ATKINS, Michael B, BUKOWSKI, Ronald M, RINI, Brian I, CHOUEIRI, Toni K, REGAN, Meredith M, WARREN, Mark A, ALI REZA GOLSHAYAN, SAHI, Chakshu, EIGL, Bernhard J, RUETHER, J. Dean, CHENG, Tina, NORTH, Scott
Published in Journal of clinical oncology (01.12.2009)
Published in Journal of clinical oncology (01.12.2009)
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Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations
Albiges, Laurence, Hakimi, A Ari, Xie, Wanling, McKay, Rana R, Simantov, Ronit, Lin, Xun, Lee, Jae-Lyun, Rini, Brian I, Srinivas, Sandy, Bjarnason, Georg A, Ernst, Scott, Wood, Lori A, Vaishamayan, Ulka N, Rha, Sun-Young, Agarwal, Neeraj, Yuasa, Takeshi, Pal, Sumanta K, Bamias, Aristotelis, Zabor, Emily C, Skanderup, Anders J, Furberg, Helena, Fay, Andre P, de Velasco, Guillermo, Preston, Mark A, Wilson, Kathryn M, Cho, Eunyoung, McDermott, David F, Signoretti, Sabina, Heng, Daniel Y C, Choueiri, Toni K
Published in Journal of clinical oncology (20.10.2016)
Published in Journal of clinical oncology (20.10.2016)
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Survival outcomes and independent response assessment with nivolumab plus ipilimumab versus sunitinib in patients with advanced renal cell carcinoma: 42-month follow-up of a randomized phase 3 clinical trial
Motzer, Robert J, Escudier, Bernard, McDermott, David F, Arén Frontera, Osvaldo, Melichar, Bohuslav, Powles, Thomas, Donskov, Frede, Plimack, Elizabeth R, Barthélémy, Philippe, Hammers, Hans J, George, Saby, Grünwald, Viktor, Porta, Camillo, Neiman, Victoria, Ravaud, Alain, Choueiri, Toni K, Rini, Brian I, Salman, Pamela, Kollmannsberger, Christian K, Tykodi, Scott S, Grimm, Marc-Oliver, Gurney, Howard, Leibowitz-Amit, Raya, Geertsen, Poul F, Amin, Asim, Tomita, Yoshihiko, McHenry, M Brent, Saggi, Shruti Shally, Tannir, Nizar M
Published in Journal for immunotherapy of cancer (01.07.2020)
Published in Journal for immunotherapy of cancer (01.07.2020)
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The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of advanced renal cell carcinoma (RCC)
Rini, Brian I., Battle, Dena, Figlin, Robert A., George, Daniel J., Hammers, Hans, Hutson, Tom, Jonasch, Eric, Joseph, Richard W., McDermott, David F., Motzer, Robert J., Pal, Sumanta K., Pantuck, Allan J., Quinn, David I., Seery, Virginia, Voss, Martin H., Wood, Christopher G., Wood, Laura S., Atkins, Michael B.
Published in Journal for immunotherapy of cancer (20.12.2019)
Published in Journal for immunotherapy of cancer (20.12.2019)
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irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial
Pignon, Jean-Christophe, Jegede, Opeyemi, Shukla, Sachet A, Braun, David A, Horak, Christine E, Wind-Rotolo, Megan, Ishii, Yuko, Catalano, Paul J, Grosha, Jonian, Flaifel, Abdallah, Novak, Jesse S, Mahoney, Kathleen M, Freeman, Gordon J, Sharpe, Arlene H, Hodi, F Stephen, Motzer, Robert J, Choueiri, Toni K, Wu, Catherine J, Atkins, Michael B, McDermott, David F, Signoretti, Sabina
Published in Clinical cancer research (01.04.2019)
Published in Clinical cancer research (01.04.2019)
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