Search Results - "McCusker, Kevin P" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

by Hinman, Andrew, Holst, Charles R, Latham, Joey C, Bruegger, Joel J, Ulas, Gözde, McCusker, Kevin P, Amagata, Akiko, Davis, Dana, Hoff, Kevin G, Kahn-Kirby, Amanda H, Kim, Virna, Kosaka, Yuko, Lee, Edgar, Malone, Stephanie A, Mei, Janet J, Richards, Steve James, Rivera, Veronica, Miller, Guy, Trimmer, Jeffrey K, Shrader, William D
Published in PloS one (15.08.2018)

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Journal Article

Modular Behavior of tauD Provides Insight into the Origin of Specificity in α-Ketoglutarate-Dependent Nonheme Iron Oxygenases

Modular Behavior of tauD Provides Insight into the Origin of Specificity in α-Ketoglutarate-Dependent Nonheme Iron Oxygenases

by McCusker, Kevin P., Klinman, Judith P.
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2009)

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The Chemistry of Peptidyltransferase Center-Targeted Antibiotics: Enzymatic Resistance and Approaches to Countering Resistance

The Chemistry of Peptidyltransferase Center-Targeted Antibiotics: Enzymatic Resistance and Approaches to Countering Resistance

by McCusker, Kevin P., Fujimori, Danica Galonić
Published in ACS chemical biology (20.01.2012)

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Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson's disease

Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson's disease

by Minnella, Angela, McCusker, Kevin P, Amagata, Akiko, Trias, Beatrice, Weetall, Marla, Latham, Joey C, O'Neill, Sloane, Wyse, Richard K, Klein, Matthew B, Trimmer, Jeffrey K
Published in PloS one (18.09.2024)

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An Active-Site Phenylalanine Directs Substrate Binding and C−H Cleavage in the α-Ketoglutarate-Dependent Dioxygenase TauD

An Active-Site Phenylalanine Directs Substrate Binding and C−H Cleavage in the α-Ketoglutarate-Dependent Dioxygenase TauD

by McCusker, Kevin P, Klinman, Judith P
Published in Journal of the American Chemical Society (14.04.2010)

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Covalent Intermediate in the Catalytic Mechanism of the Radical S‑Adenosyl‑l‑methionine Methyl Synthase RlmN Trapped by Mutagenesis

Covalent Intermediate in the Catalytic Mechanism of the Radical S‑Adenosyl‑l‑methionine Methyl Synthase RlmN Trapped by Mutagenesis

by McCusker, Kevin P, Medzihradszky, Katalin F, Shiver, Anthony L, Nichols, Robert J, Yan, Feng, Maltby, David A, Gross, Carol A, Galonić Fujimori, Danica
Published in Journal of the American Chemical Society (31.10.2012)

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Mechanistic Investigations of 1-Aminocyclopropane 1-Carboxylic Acid Oxidase with Alternate Cyclic and Acyclic Substrates

Mechanistic Investigations of 1-Aminocyclopropane 1-Carboxylic Acid Oxidase with Alternate Cyclic and Acyclic Substrates

by Thrower, Julia, Mirica, Liviu M, McCusker, Kevin P, Klinman, Judith P
Published in Biochemistry (Easton) (31.10.2006)

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18O Kinetic Isotope Effects in Non-Heme Iron Enzymes: Probing the Nature of Fe/O2 Intermediates

18O Kinetic Isotope Effects in Non-Heme Iron Enzymes: Probing the Nature of Fe/O2 Intermediates

by Mirica, Liviu M, McCusker, Kevin P, Munos, Jeffrey W, Liu, Hung-wen, Klinman, Judith P
Published in Journal of the American Chemical Society (02.07.2008)

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Use of a tyrosine hydroxylase mutant enzyme with reduced metal affinity allows detection of activity with cobalt in place of iron

Use of a tyrosine hydroxylase mutant enzyme with reduced metal affinity allows detection of activity with cobalt in place of iron

by Ellis, Holly R., McCusker, Kevin P., Fitzpatrick, Paul F.
Published in Archives of biochemistry and biophysics (15.12.2002)

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Modular behavior of tauD provides insight into the origin of specificity in [alpha]-ketoglutarate-dependent nonheme iron oxygenases

Modular behavior of tauD provides insight into the origin of specificity in [alpha]-ketoglutarate-dependent nonheme iron oxygenases

by McCusker, Kevin P, Klinman, Judith P
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2009)

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Facile synthesis of 1,1-[ 2H 2]-2-methylaminoethane-1-sulfonic acid as a substrate for taurine α ketoglutarate dioxygenase (TauD)

Facile synthesis of 1,1-[ 2H 2]-2-methylaminoethane-1-sulfonic acid as a substrate for taurine α ketoglutarate dioxygenase (TauD)

by McCusker, Kevin P., Klinman, Judith P.
Published in Tetrahedron letters (11.02.2009)

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Covalent Intermediate in the Catalytic Mechanism of the Radical SAM Methyl Synthase RlmN Trapped by Mutagenesis

Covalent Intermediate in the Catalytic Mechanism of the Radical SAM Methyl Synthase RlmN Trapped by Mutagenesis

by McCusker, Kevin P., Medzihradszky, Katalin F., Shiver, Anthony L., Nichols, Robert J., Yan, Feng, Maltby, David A., Gross, Carol A., Fujimori, Danica Galonić
Published in Journal of the American Chemical Society (22.10.2012)

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Journal Article

18 O Kinetic Isotope Effects in Non-Heme Iron Enzymes: Probing the Nature of Fe/O 2 Intermediates

18 O Kinetic Isotope Effects in Non-Heme Iron Enzymes: Probing the Nature of Fe/O 2 Intermediates

by Mirica, Liviu M., McCusker, Kevin P., Munos, Jeffrey W., Liu, Hung-wen, Klinman, Judith P.
Published in Journal of the American Chemical Society (01.07.2008)

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METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

by MILLER, Guy M, HOLST, Charles R, BRUEGGER, Joel J, RICHARDS, Steven J, TRIMMER, Jeffery K, LEE, Edgar P, MCCUSKER, Kevin P, ULAS, Gözde, MALONE, Stephanie A, DAVIS, Dana, KLEIN, Matthew B, SHRADER, William, HINMAN, Andrew W, LATHAM, Joey C, KAHN-KIRBY, Amanda H
Year of Publication 18.08.2022

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Patent

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

by MILLER, Guy M, HOLST, Charles R, BRUEGGER, Joel J, RICHARDS, Steven J, TRIMMER, Jeffery K, LEE, Edgar P, MCCUSKER, Kevin P, ULAS, Gozde, MALONE, Stephanie A, DAVIS, Dana, KLEIN, Matthew B, HINMAN, Andrew W, SHRADER, William D, LATHAM, Joey C, KAHN-KIRBY, Amanda H
Year of Publication 23.04.2020

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Patent

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

by MILLER, Guy M, HOLST, Charles R, BRUEGGER, Joel J, RICHARDS, Steven J, TRIMMER, Jeffery K, LEE, Edgar P, MCCUSKER, Kevin P, ULAS, Gözde, MALONE, Stephanie A, DAVIS, Dana, KLEIN, Matthew B, HINMAN, Andrew W, SHRADER, William D, LATHAM, Joey C, KAHN-KIRBY, Amanda H
Year of Publication 18.10.2018

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Patent

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS

by HOLST, CHARLES R, LATHAM, JOEY C, LEE, EDGAR P, MALONE, STEPHANIE A, MILLER, GUY M, RICHARDS, STEVEN J, BRUEGGER, JOEL J, ULAS, GOZDE, TRIMMER, JEFFERY K, KLEIN, MATTHEW B, KAHN-KIRBY, AMANDA H, SHRADER, WILLIAM D, MCCUSKER, KEVIN P, DAVIS, DANA, HINMAN, ANDREW W
Year of Publication 18.10.2018

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Patent