Plasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes Mellitus
Alshehry, Zahir H, Mundra, Piyushkumar A, Barlow, Christopher K, Mellett, Natalie A, Wong, Gerard, McConville, Malcolm J, Simes, John, Tonkin, Andrew M, Sullivan, David R, Barnes, Elizabeth H, Nestel, Paul J, Kingwell, Bronwyn A, Marre, Michel, Neal, Bruce, Poulter, Neil R, Rodgers, Anthony, Williams, Bryan, Zoungas, Sophia, Hillis, Graham S, Chalmers, John, Woodward, Mark, Meikle, Peter J
Published in Circulation (New York, N.Y.) (22.11.2016)
Published in Circulation (New York, N.Y.) (22.11.2016)
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A Toxoplasma gondii Gluconeogenic Enzyme Contributes to Robust Central Carbon Metabolism and Is Essential for Replication and Virulence
Blume, Martin, Nitzsche, Richard, Sternberg, Ulrich, Gerlic, Motti, Masters, Seth L., Gupta, Nishith, McConville, Malcolm J.
Published in Cell host & microbe (12.08.2015)
Published in Cell host & microbe (12.08.2015)
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Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance
Yang, Tuo, Yeoh, Lee M., Tutor, Madel V., Dixon, Matthew W., McMillan, Paul J., Xie, Stanley C., Bridgford, Jessica L., Gillett, David L., Duffy, Michael F., Ralph, Stuart A., McConville, Malcolm J., Tilley, Leann, Cobbold, Simon A.
Published in Cell reports (Cambridge) (26.11.2019)
Published in Cell reports (Cambridge) (26.11.2019)
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Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments
Srivastava, Anubhav, Philip, Nisha, Hughes, Katie R, Georgiou, Konstantina, MacRae, James I, Barrett, Michael P, Creek, Darren J, McConville, Malcolm J, Waters, Andrew P
Published in PLoS pathogens (27.12.2016)
Published in PLoS pathogens (27.12.2016)
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Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking
Kennedy, Kit, Cobbold, Simon A, Hanssen, Eric, Birnbaum, Jakob, Spillman, Natalie J, McHugh, Emma, Brown, Hannah, Tilley, Leann, Spielmann, Tobias, McConville, Malcolm J, Ralph, Stuart A
Published in PLoS biology (18.07.2019)
Published in PLoS biology (18.07.2019)
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The natural function of the malaria parasite’s chloroquine resistance transporter
Shafik, Sarah H., Cobbold, Simon A., Barkat, Kawthar, Richards, Sashika N., Lancaster, Nicole S., Llinás, Manuel, Hogg, Simon J., Summers, Robert L., McConville, Malcolm J., Martin, Rowena E.
Published in Nature communications (06.08.2020)
Published in Nature communications (06.08.2020)
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NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease
Tye, Hazel, Yu, Chien-Hsiung, Simms, Lisa A., de Zoete, Marcel R., Kim, Man Lyang, Zakrzewski, Martha, Penington, Jocelyn S., Harapas, Cassandra R., Souza-Fonseca-Guimaraes, Fernando, Wockner, Leesa F., Preaudet, Adele, Mielke, Lisa A., Wilcox, Stephen A., Ogura, Yasunori, Corr, Sinead C., Kanojia, Komal, Kouremenos, Konstantinos A., De Souza, David P., McConville, Malcolm J., Flavell, Richard A., Gerlic, Motti, Kile, Benjamin T., Papenfuss, Anthony T., Putoczki, Tracy L., Radford-Smith, Graham L., Masters, Seth L.
Published in Nature communications (13.09.2018)
Published in Nature communications (13.09.2018)
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Induction of a stringent metabolic response in intracellular stages of Leishmania mexicana leads to increased dependence on mitochondrial metabolism
Saunders, Eleanor C, Ng, William W, Kloehn, Joachim, Chambers, Jennifer M, Ng, Milica, McConville, Malcolm J
Published in PLoS pathogens (01.01.2014)
Published in PLoS pathogens (01.01.2014)
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Metabolomics-Based Screening of the Malaria Box Reveals both Novel and Established Mechanisms of Action
Creek, Darren J, Chua, Hwa H, Cobbold, Simon A, Nijagal, Brunda, MacRae, James I, Dickerman, Benjamin K, Gilson, Paul R, Ralph, Stuart A, McConville, Malcolm J
Published in Antimicrobial agents and chemotherapy (01.11.2016)
Published in Antimicrobial agents and chemotherapy (01.11.2016)
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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy
Rolando, Monica, Escoll, Pedro, Nora, Tamara, Botti, Joëlle, Boitez, Valérie, Bedia, Carmen, Daniels, Craig, Abraham, Gilu, Stogios, Peter J., Skarina, Tatiana, Christophe, Charlotte, Dervins-Ravault, Delphine, Cazalet, Christel, Hilbi, Hubert, Rupasinghe, Thusitha W. T., Tull, Dedreia, McConville, Malcolm J., Ong, Sze Ying, Hartland, Elizabeth L., Codogno, Patrice, Levade, Thierry, Naderer, Thomas, Savchenko, Alexei, Buchrieser, Carmen
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2016)
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Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum
MacRae, James I, Dixon, Matthew Wa, Dearnley, Megan K, Chua, Hwa H, Chambers, Jennifer M, Kenny, Shannon, Bottova, Iveta, Tilley, Leann, McConville, Malcolm J
Published in BMC biology (13.06.2013)
Published in BMC biology (13.06.2013)
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Endosymbiosis undone by stepwise elimination of the plastid in a parasitic dinoflagellate
Gornik, Sebastian G., Febrimarsa, Cassin, Andrew M., MacRae, James I., Ramaprasad, Abhinay, Rchiad, Zineb, McConville, Malcolm J., Bacic, Antony, McFadden, Geoffrey I., Pain, Arnab, Waller, Ross F.
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
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Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii
Fairweather, Stephen J, Rajendran, Esther, Blume, Martin, Javed, Kiran, Steinhöfel, Birte, McConville, Malcolm J, Kirk, Kiaran, Bröer, Stefan, van Dooren, Giel G
Published in PLoS pathogens (25.08.2021)
Published in PLoS pathogens (25.08.2021)
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The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family
Parker, Kathryn E R, Fairweather, Stephen J, Rajendran, Esther, Blume, Martin, McConville, Malcolm J, Bröer, Stefan, Kirk, Kiaran, van Dooren, Giel G
Published in PLoS pathogens (01.02.2019)
Published in PLoS pathogens (01.02.2019)
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Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
Uboldi, Alessandro D, Wilde, Mary-Louise, McRae, Emi A, Stewart, Rebecca J, Dagley, Laura F, Yang, Luning, Katris, Nicholas J, Hapuarachchi, Sanduni V, Coffey, Michael J, Lehane, Adele M, Botte, Cyrille Y, Waller, Ross F, Webb, Andrew I, McConville, Malcolm J, Tonkin, Christopher J
Published in PLoS biology (01.09.2018)
Published in PLoS biology (01.09.2018)
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BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei
Oppenheim, Rebecca D, Creek, Darren J, Macrae, James I, Modrzynska, Katarzyna K, Pino, Paco, Limenitakis, Julien, Polonais, Valerie, Seeber, Frank, Barrett, Michael P, Billker, Oliver, McConville, Malcolm J, Soldati-Favre, Dominique
Published in PLoS pathogens (01.07.2014)
Published in PLoS pathogens (01.07.2014)
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