Search Results - "McComas, Casey" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348)

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348)

by Fensome, Andrew, Adams, William R, Adams, Andrea L, Berrodin, Tom J, Cohen, Jeff, Huselton, Christine, Illenberger, Arthur, Kern, Jeffrey C, Hudak, Valerie A, Marella, Michael A, Melenski, Edward G, McComas, Casey C, Mugford, Cheryl A, Slayden, Ov D, Yudt, Matthew, Zhang, Zhiming, Zhang, Puwen, Zhu, Yuan, Winneker, Richard C, Wrobel, Jay E
Published in Journal of medicinal chemistry (27.03.2008)

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Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876

Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876

by McComas, Casey C., Palani, Anandan, Chang, Wei, Holloway, M. Katharine, Lesburg, Charles A., Li, Peng, Liverton, Nigel, Meinke, Peter T., Olsen, David B., Peng, Xuanjia, Soll, Richard M., Ummat, Ajay, Wu, Jie, Wu, Jin, Zorn, Nicolas, Ludmerer, Steven W.
Published in ChemMedChem (07.09.2017)

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Partitioning the Loss in Vancomycin Binding Affinity for d-Ala-d-Lac into Lost H-Bond and Repulsive Lone Pair Contributions

Partitioning the Loss in Vancomycin Binding Affinity for d-Ala-d-Lac into Lost H-Bond and Repulsive Lone Pair Contributions

by McComas, Casey C, Crowley, Brendan M, Boger, Dale L
Published in Journal of the American Chemical Society (06.08.2003)

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Front Cover: Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876 (ChemMedChem 17/2017)

Front Cover: Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876 (ChemMedChem 17/2017)

by McComas, Casey C., Palani, Anandan, Chang, Wei, Holloway, M. Katharine, Lesburg, Charles A., Li, Peng, Liverton, Nigel, Meinke, Peter T., Olsen, David B., Peng, Xuanjia, Soll, Richard M., Ummat, Ajay, Wu, Jie, Wu, Jin, Zorn, Nicolas, Ludmerer, Steven W.
Published in ChemMedChem (07.09.2017)

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Facile functionalization at the C2 position of a highly substituted benzofuran

Facile functionalization at the C2 position of a highly substituted benzofuran

by He, Shuwen, Li, Peng, Dai, Xing, McComas, Casey C., Du, Chunyan, Wang, Ping, Lai, Zhong, Liu, Hong, Yin, Jingjun, Bulger, Paul G., Dang, Qun, Xiao, Dong, Zorn, Nicolas, Peng, Xuanjia, Nargund, Ravi P., Palani, Anandan
Published in Tetrahedron letters (02.04.2014)

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A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization

A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization

by He, Shuwen, Li, Peng, Dai, Xing, McComas, Casey C., Huang, Hongling, Zhan, Chaoliang, Chang, Liang, Liu, Yuehui, Chen, Shaojun, Lai, Zhong, Liu, Hong, Yin, Jingjun, Dang, Qun, Xiao, Dong, Zorn, Nicolas, Peng, Xuanjia, Nargund, Ravi P., Palani, Anandan
Published in Tetrahedron letters (17.07.2013)

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Total Synthesis of the Ristocetin Aglycon

Total Synthesis of the Ristocetin Aglycon

by Crowley, Brendan M, Mori, Yoshiki, McComas, Casey C, Tang, Datong, Boger, Dale L
Published in Journal of the American Chemical Society (07.04.2004)

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A new generation of progesterone receptor modulators

A new generation of progesterone receptor modulators

by Winneker, Richard C., Fensome, Andrew, Zhang, Puwen, Yudt, Matthew R., McComas, Casey C., Unwalla, Rayomond J.
Published in Steroids (01.08.2008)

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Discovery of Novel Selective Norepinephrine Reuptake Inhibitors: 4-[3-Aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231)

Discovery of Novel Selective Norepinephrine Reuptake Inhibitors: 4-[3-Aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231)

by O’Neill, David J, Adedoyin, Adedayo, Alfinito, Peter D, Bray, Jenifer A, Cosmi, Scott, Deecher, Darlene C, Fensome, Andrew, Harrison, Jim, Leventhal, Liza, Mann, Charles, McComas, Casey C, Sullivan, Nicole R, Spangler, Taylor B, Uveges, Albert J, Trybulski, Eugene J, Whiteside, Garth T, Zhang, Puwen
Published in Journal of medicinal chemistry (10.06.2010)

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Structure–activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril cores

Structure–activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril cores

by Fensome, Andrew, Goldberg, Joel, McComas, Casey C., Trybulski, Eugene J., Woodworth, Richard P., Deecher, Darlene C., Whiteside, Garth T., Zhang, Puwen
Published in Bioorganic & medicinal chemistry letters (01.03.2010)

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Synthesis and activity of novel 1-or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors

Synthesis and activity of novel 1-or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors

by PUWEN ZHANG, TEREFENKO, Eugene A, MCCOMAS, Casey C, MAHANEY, Paige E, AN VU, TRYBULSKI, Eugene, KOURY, Elizabeth, JOHNSTON, Grace, BRAY, Jenifer, DEECHER, Darlene
Published in Bioorganic & medicinal chemistry (01.12.2008)

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A general approach to access 5,6-dihydroindolo-naphthyridine ring system

A general approach to access 5,6-dihydroindolo-naphthyridine ring system

by He, Shuwen, Li, Peng, Dai, Xing, Liu, Hong, Lai, Zhong, Xiao, Dong, McComas, Casey C., Du, Chunyan, Liu, Yuehui, Yin, Jingjun, Dang, Qun, Zorn, Nicolas, Peng, Xuanjia, Nargund, Ravi P., Palani, Anandan
Published in Tetrahedron letters (05.04.2017)

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Synthesis and activity of a new class of dual acting norepinephrine and serotonin reuptake inhibitors: 3-(1 H-indol-1-yl)-3-arylpropan-1-amines

Synthesis and activity of a new class of dual acting norepinephrine and serotonin reuptake inhibitors: 3-(1 H-indol-1-yl)-3-arylpropan-1-amines

by Mahaney, Paige E., Vu, An T., McComas, Casey C., Zhang, Puwen, Nogle, Lisa M., Watts, William L., Sarkahian, Ani, Leventhal, Liza, Sullivan, Nicole R., Uveges, Albert J., Trybulski, Eugene J.
Published in Bioorganic & medicinal chemistry (15.12.2006)

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Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: A new class of selective norepinephrine reuptake inhibitors

Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: A new class of selective norepinephrine reuptake inhibitors

by McComas, Casey C., Vu, An T., Mahaney, Paige E., Cohn, Stephen T., Fensome, Andrew, Marella, Michael A., Nogle, Lisa, Trybulski, Eugene J., Ye, Fei, Zhang, Puwen, Alfinito, Peter, Bray, Jenifer, Johnston, Grace, Koury, Elizabeth, Deecher, Darlene C.
Published in Bioorganic & medicinal chemistry (15.09.2008)

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Synthesis and evaluation of methyl ether derivatives of the vancomycin, teicoplanin, and ristocetin aglycon methyl esters

Synthesis and evaluation of methyl ether derivatives of the vancomycin, teicoplanin, and ristocetin aglycon methyl esters

by McComas, Casey C., Crowley, Brendan M., Hwang, Inkyu, Boger, Dale L.
Published in Bioorganic & medicinal chemistry letters (01.09.2003)

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Large-Scale Synthesis of a Selective Inhibitor of the Norepinephrine Transporter: Mechanistic Aspects of Conversion of Indolinone Diol to Indolinone Aminoalcohol and Process Implications

Large-Scale Synthesis of a Selective Inhibitor of the Norepinephrine Transporter: Mechanistic Aspects of Conversion of Indolinone Diol to Indolinone Aminoalcohol and Process Implications

by Alimardanov, Asaf, Gontcharov, Alexander, Nikitenko, Antonia, Chan, Anita W, Ding, Zhixian, Ghosh, Mousumi, Levent, Mahmut, Raveendranath, Panolil, Ren, Jianxin, Zhou, Maotang, Mahaney, Paige E, McComas, Casey C, Ashcroft, Joseph, Potoski, John R
Published in Organic process research & development (18.09.2009)

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Synthesis of (±)-Madindolines and Chemical Models. Studies of Chemical Reactivity

Synthesis of (±)-Madindolines and Chemical Models. Studies of Chemical Reactivity

by McComas, Casey C, Perales, Joe B, Van Vranken, David L
Published in Organic letters (11.07.2002)

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1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: Potent, Selective, and Orally Efficacious Norepinephrine Reuptake Inhibitors

1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: Potent, Selective, and Orally Efficacious Norepinephrine Reuptake Inhibitors

by Zhang, Puwen, Terefenko, Eugene A., Bray, Jenifer, Deecher, Darlene, Fensome, Andrew, Harrison, Jim, Kim, Callain, Koury, Elizabeth, Mark, Lilly, McComas, Casey C., Mugford, Cheryl A., Trybulski, Eugene J., Vu, An T., Whiteside, Garth T., Mahaney, Paige E.
Published in Journal of medicinal chemistry (24.09.2009)

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A new and improved method for deglycosidation of glycopeptide antibiotics exemplified with vancomycin, ristocetin, and ramoplanin

A new and improved method for deglycosidation of glycopeptide antibiotics exemplified with vancomycin, ristocetin, and ramoplanin

by Wanner, Jutta, Tang, Datong, McComas, Casey C, Crowley, Brendan M, Jiang, Wanlong, Moss, Jason, Boger, Dale L
Published in Bioorganic & medicinal chemistry letters (24.03.2003)

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Neutral Ru(η5-pyrrole) Complexes. Synthesis and Structure of Diazaruthenocenes and Ru(1-3:5,6-η5-C8H11)(η5-pyrrole) Complexes

Neutral Ru(η5-pyrrole) Complexes. Synthesis and Structure of Diazaruthenocenes and Ru(1-3:5,6-η5-C8H11)(η5-pyrrole) Complexes

by McComas, Casey C, Ziller, Joseph W, Van Vranken, David L
Published in Organometallics (24.07.2000)

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