Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication
Clark, Jeremy L, Hollecker, Laurent, Mason, J. Christian, Stuyver, Lieven J, Tharnish, Phillip M, Lostia, Stefania, McBrayer, Tamara R, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J, Furman, Phillip A, Stec, Wojciech J, Patterson, Steven E, Pankiewicz, Krzysztof W
Published in Journal of medicinal chemistry (25.08.2005)
Published in Journal of medicinal chemistry (25.08.2005)
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Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture
STUYVER, Lieven J, WHITAKER, Tony, RACHAKONDA, Suguna, WATANABE, Kyoichi A, OTTO, Michael J, SCHINAZI, Raymond F, MCBRAYER, Tamara R, HERNANDEZ-SANTIAGO, Brenda I, LOSTIA, Stefania, THARNISH, Phillip M, RAMESH, Mangala, CHU, Chung K, JORDAN, Robert, JUNXING SHI
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)
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Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites
Stuyver, Lieven J, McBrayer, Tamara R, Tharnish, Phillip M, Hassan, Abdalla E A, Chu, Chung K, Pankiewicz, Krzysztof W, Watanabe, Kyochi A, Schinazi, Raymond F, Otto, Michael J
Published in Journal of Virology (01.10.2003)
Published in Journal of Virology (01.10.2003)
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Journal Article
Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine
Stuyver, Lieven J, McBrayer, Tamara R, Whitaker, Tony, Tharnish, Phillip M, Ramesh, Mangala, Lostia, Stefania, Cartee, Leanne, Shi, Junxing, Hobbs, Ann, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J
Published in Antimicrobial Agents and Chemotherapy (01.02.2004)
Published in Antimicrobial Agents and Chemotherapy (01.02.2004)
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Journal Article
[beta]-D-2'-C-Me-2,6-diaminopurine ribonucleoside phosphoramidates are potent and selective inhibitors of hepatitis C virus (HCV) and are bioconverted intracellularly to bioactive 2,6-diaminopurine- and guanosine-5'-triphosphate forms
Schinazi, R F, Zhou, L, Zhang, H-W, Tao, S, Bassit, L, Whitaker, T, McBrayer, T R, Ehteshami, M, Amiralaei, S, Detorio, M, Coats, S J
Published in Antiviral therapy (01.01.2013)
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Published in Antiviral therapy (01.01.2013)
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Inhibition of Hepatitis C Replicon RNA Synthesis by β-D-2′-deoxy-2′-fluoro-2′-C-Methylcytidine: A Specific Inhibitor of Hepatitis C Virus Replication
Stuyver, Lieven J, McBrayer, Tamara R, Tharnish, Phillip M, Clark, Jeremy, Hollecker, Laurent, Lostia, Stefania, Nachman, Tammy, Grier, Jason, Bennett, Matthew A, Xie, Meng-Yu, Schinazi, Raymond F, Morrey, John D, Julander, Justin L, Furman, Phillip A, Otto, Michael J
Published in Antiviral chemistry & chemotherapy (2006)
Published in Antiviral chemistry & chemotherapy (2006)
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Synthesis of N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl) -vic-triazolo[4,5-b]pyridin-5-one, a Novel Compound with Anti-Hepatitis C Virus Activity
Wang, P, Hollecker, L, Pankiewicz, K W, Patterson, SE, Whitaker, T, McBrayer, T R, Tharnish, P M, Sidwell, R W, Stuyver, L J, Otto, MJ, Schinazi, R F, Watanabe, KA
Published in Journal of medicinal chemistry (18.11.2004)
Published in Journal of medicinal chemistry (18.11.2004)
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Journal Article
Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication
Clark, Jeremy L., Mason, J. Christian, Hollecker, Laurent, Stuyver, Lieven J., Tharnish, Phillip M., McBrayer, Tamara R., Otto, Michael J., Furman, Phillip A., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Journal Article
Synthesis of N-3,5 '-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity
Wang, PY, Hollecker, L, Pankiewicz, KW, Patterson, SE, Whitaker, T, McBrayer, TR, Tharnish, PM, Sidwell, RW, Stuyver, LJ, Otto, MJ, Schinazi, RF, Watanabe, KA
Published in Journal of medicinal chemistry (18.11.2004)
Published in Journal of medicinal chemistry (18.11.2004)
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Journal Article
Synthesis of β-Enantiomers of N4-Hydroxy-3′-Deoxy-Pyrimidine Nucleosides and Their Evaluation against Bovine Viral Diarrhoea Virus and Hepatitis C Virus in Cell Culture
Hollecker, Laurent, Choo, Hyunah, Chong, Youhoon, Chu, Chung K, Lostia, Stefania, McBrayer, Tamara R, Stuyver, Lieven J, Mason, J Christian, Du, Jinfa, Rachakonda, Suguna, Shi, Junxing, Schinazi, Raymond F, Watanabe, Kyochi A
Published in Antiviral chemistry & chemotherapy (01.02.2004)
Published in Antiviral chemistry & chemotherapy (01.02.2004)
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Potent antiviral effect of Reverset in HIV-1-infected adults following a single oral dose
STUYVER, Lieven J, MCBRAYER, Tamara R, SCHÜRMANN, Dirk, KRAVEC, Irena, BEARD, Amanda, CARTEE, Leanne, SCHINAZI, Raymond F, DE LA ROSA, Abel, MURPHY, Robert L, OTTO, Michael J
Published in Antiviral therapy (01.08.2004)
Published in Antiviral therapy (01.08.2004)
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Journal Article
SYNTHESIS OF N 3 ,5′-CYCLO-4-(β-D-RIBOFURANOSYL)- VIC -TRIAZOLO[4,5- b ]PYRIDIN-5-ONE AND ITS 3′-DEOXYSUGAR ANALOGUE AS POTENTIAL ANTI-HEPATITIS C VIRUS AGENTS
Wang, Peiyuan, Hollecker, Laurent, Pankiewicz, Krzysztof W., Patterson, Steven E., Whitaker, Tony, McBrayer, Tamara R., Tharnish, Phillip M., Stuyver, Lieven J., Schinazi, Raymond F., Otto, Michael J., Watanabe, Kyoichi A.
Published in Nucleosides, nucleotides & nucleic acids (01.04.2005)
Published in Nucleosides, nucleotides & nucleic acids (01.04.2005)
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Journal Article
SYNTHESIS AND IN VITRO ANTI-HCV ACTIVITY OF β-D- and L-2′-DEOXY-2′-FLUORORIBONUCLEOSIDES
Shi, Junxing, Du, Jinfa, Ma, Tianwei, Pankiewicz, Krzysztof, Patterson, Steven E., Hassan, Abdalla E. A., Tharnish, Phillip M., McBrayer, Tamara R., Lostia, Stefania, Stuyver, Lieven J., Watanabe, Kyoichi A., Chu, Chung K., Schinazi, Raymond F., Otto, Michael J.
Published in Nucleosides, nucleotides & nucleic acids (01.04.2005)
Published in Nucleosides, nucleotides & nucleic acids (01.04.2005)
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