Bioactivation of 6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to Reactive Intermediates That Bind Covalently to Macromolecules and Produce Genotoxicity1
Zhao, Zhiyang, Koeplinger, Kenneth A, Padbury, Guy E, Hauer, Michael J, Bundy, Gordon L, Banitt, Lee S, Schwartz, Theresa M, Zimmermann, David C, Harbach, Philip R, Mayo, Judy K, Aaron, C. Sidney
Published in Chemical research in toxicology (27.11.1996)
Published in Chemical research in toxicology (27.11.1996)
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Contribution of serum protein association to discrepancy between the in vivo and in vitro UDS results for 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843)
Zhao, Z, Koeplinger, K A, Padbury, G E, Aaron, C S, Harbach, P R, Mayo, J K, Mattes, W B, Bundy, G L
Published in Mutation research (12.12.1997)
Published in Mutation research (12.12.1997)
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Synthesis of Novel 2,4-Diaminopyrrolo[2,3-d]pyrimidines with Antioxidant, Neuroprotective, and Antiasthma Activity
Bundy, Gordon L, Ayer, Donald E, Banitt, Lee S, Belonga, Kenneth L, Mizsak, Stephen A, Palmer, John R, Tustin, James M, Chin, Jia En, Hall, Edward D
Published in Journal of medicinal chemistry (01.10.1995)
Published in Journal of medicinal chemistry (01.10.1995)
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Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity
Zhao, Z, Koeplinger, K A, Padbury, G E, Hauer, M J, Bundy, G L, Banitt, L S, Schwartz, T M, Zimmermann, D C, Harbach, P R, Mayo, J K, Aaron, C S
Published in Chemical research in toxicology (01.12.1996)
Published in Chemical research in toxicology (01.12.1996)
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Transfection of a mutant regulatory subunit gene of cAMP-dependent protein kinase causes increased drug sensitivity and decreased expression of P-glycoprotein
Abraham, Irene, Chin, Khew-Voon, Gottesman, Michael M., Mayo, Judy K., Sampson, Kathleen E.
Published in Experimental cell research (01.07.1990)
Published in Experimental cell research (01.07.1990)
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Bioactivation of 6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7 H -pyrrolo[2,3- d ]pyrimidine (U-89843) to Reactive Intermediates That Bind Covalently to Macromolecules and Produce Genotoxicity 1
Zhao, Zhiyang, Koeplinger, Kenneth A., Padbury, Guy E., Hauer, Michael J., Bundy, Gordon L., Banitt, Lee S., Schwartz, Theresa M., Zimmermann, David C., Harbach, Philip R., Mayo, Judy K., Aaron, C. Sidney
Published in Chemical research in toxicology (01.01.1996)
Published in Chemical research in toxicology (01.01.1996)
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Phorbol myristate acetate inhibits growth in S49 cells: isolation of resistant variants
Leach, K L, Powers, E A, Mayo, J K, Abraham, I, Burnett, B A, Groppi, V E
Published in Journal of cellular physiology (01.09.1987)
Published in Journal of cellular physiology (01.09.1987)
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