SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair
Kanu, N, Grönroos, E, Martinez, P, Burrell, R A, Yi Goh, X, Bartkova, J, Maya-Mendoza, A, Mistrík, M, Rowan, A J, Patel, H, Rabinowitz, A, East, P, Wilson, G, Santos, C R, McGranahan, N, Gulati, S, Gerlinger, M, Birkbak, N J, Joshi, T, Alexandrov, L B, Stratton, M R, Powles, T, Matthews, N, Bates, P A, Stewart, A, Szallasi, Z, Larkin, J, Bartek, J, Swanton, C
Published in Oncogene (12.11.2015)
Published in Oncogene (12.11.2015)
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Journal Article
Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1
Ahmed, A, Yang, J, Maya-Mendoza, A, Jackson, D A, Ashcroft, M
Published in Cell death & disease (01.05.2011)
Published in Cell death & disease (01.05.2011)
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Journal Article
Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration
Maya‐Mendoza, Apolinar, Hernández‐Muñoz, Rolando, Gariglio, Patricio, Aranda‐Anzaldo, Armando
Published in Nucleic acids research (01.11.2003)
Published in Nucleic acids research (01.11.2003)
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Journal Article
High speed of fork progression induces DNA replication stress and genomic instability
Maya-Mendoza, Apolinar, Moudry, Pavel, Merchut-Maya, Joanna Maria, Lee, MyungHee, Strauss, Robert, Bartek, Jiri
Published in Nature (London) (01.07.2018)
Published in Nature (London) (01.07.2018)
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Journal Article
p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways
Lindström, Mikael S., Bartek, Jiri, Maya-Mendoza, Apolinar
Published in Cell death and differentiation (01.05.2022)
Published in Cell death and differentiation (01.05.2022)
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Journal Article
The nexus of nuclear envelope dynamics, circular economy and cancer cell pathophysiology
Keuper, Kristina, Bartek, Jiri, Maya-Mendoza, Apolinar
Published in European journal of cell biology (01.06.2024)
Published in European journal of cell biology (01.06.2024)
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Journal Article
Autophagy role(s) in response to oncogenes and DNA replication stress
Vanzo, Riccardo, Bartkova, Jirina, Merchut-Maya, Joanna Maria, Hall, Arnaldur, Bouchal, Jan, Dyrskjøt, Lars, Frankel, Lisa B., Gorgoulis, Vassilis, Maya-Mendoza, Apolinar, Jäättelä, Marja, Bartek, Jiri
Published in Cell death and differentiation (01.03.2020)
Published in Cell death and differentiation (01.03.2020)
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Journal Article
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
Galanos, Panagiotis, Vougas, Konstantinos, Walter, David, Polyzos, Alexander, Maya-Mendoza, Apolinar, Haagensen, Emma J., Kokkalis, Antonis, Roumelioti, Fani-Marlen, Gagos, Sarantis, Tzetis, Maria, Canovas, Begoña, Igea, Ana, Ahuja, Akshay K., Zellweger, Ralph, Havaki, Sofia, Kanavakis, Emanuel, Kletsas, Dimitris, Roninson, Igor B., Garbis, Spiros D., Lopes, Massimo, Nebreda, Angel, Thanos, Dimitris, Blow, J. Julian, Townsend, Paul, Sørensen, Claus Storgaard, Bartek, Jiri, Gorgoulis, Vassilis G.
Published in Nature cell biology (01.07.2016)
Published in Nature cell biology (01.07.2016)
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Journal Article
Regulation of replication fork speed: Mechanisms and impact on genomic stability
Merchut-Maya, Joanna Maria, Bartek, Jiri, Maya-Mendoza, Apolinar
Published in DNA repair (01.09.2019)
Published in DNA repair (01.09.2019)
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Journal Article
MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination
Lutzmann, Malik, Grey, Corinne, Traver, Sabine, Ganier, Olivier, Maya-Mendoza, Apolinar, Ranisavljevic, Noemie, Bernex, Florence, Nishiyama, Atsuya, Montel, Nathalie, Gavois, Elodie, Forichon, Luc, de Massy, Bernard, Méchali, Marcel
Published in Molecular cell (24.08.2012)
Published in Molecular cell (24.08.2012)
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Journal Article
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway
Maynard, Scott, Hall, Arnaldur, Galanos, Panagiotis, Rizza, Salvatore, Yamamoto, Tatsuro, Gram, Helena Hagner, Munk, Sebastian H N, Shoaib, Muhammad, Sørensen, Claus Storgaard, Bohr, Vilhelm A, Lerdrup, Mads, Maya-Mendoza, Apolinar, Bartek, Jiri
Published in Nucleic acids research (23.09.2022)
Published in Nucleic acids research (23.09.2022)
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Journal Article
A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
Zampetidis, Christos P., Galanos, Panagiotis, Angelopoulou, Andriani, Zhu, Yajie, Polyzou, Aikaterini, Karamitros, Timokratis, Kotsinas, Athanassios, Lagopati, Nefeli, Mourkioti, Ioanna, Mirzazadeh, Reza, Polyzos, Alexandros, Garnerone, Silvano, Mizi, Athanasia, Gusmao, Eduardo G., Sofiadis, Konstantinos, Gál, Zita, Larsen, Dorthe H., Pefani, Dafni-Eleftheria, Demaria, Marco, Tsirigos, Aristotelis, Crosetto, Nicola, Maya-Mendoza, Apolinar, Papaspyropoulos, Angelos, Evangelou, Konstantinos, Bartek, Jiri, Papantonis, Argyris, Gorgoulis, Vassilis G.
Published in Molecular cell (02.12.2021)
Published in Molecular cell (02.12.2021)
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Journal Article
BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
Rasmussen, Rikke D., Gajjar, Madhavsai K., Tuckova, Lucie, Jensen, Kamilla E., Maya-Mendoza, Apolinar, Holst, Camilla B., Møllgaard, Kjeld, Rasmussen, Jane S., Brennum, Jannick, Bartek, Jiri, Syrucek, Martin, Sedlakova, Eva, Andersen, Klaus K., Frederiksen, Marie H., Bartek, Jiri, Hamerlik, Petra
Published in Nature communications (15.11.2016)
Published in Nature communications (15.11.2016)
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Journal Article
Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress
Young, Lucy A, O'Connor, Lenka Oplustil, de Renty, Christelle, Veldman-Jones, Margaret H, Dorval, Thierry, Wilson, Zena, Jones, David R, Lawson, Deborah, Odedra, Rajesh, Maya-Mendoza, Apolinar, Reimer, Corinne, Bartek, Jiri, Lau, Alan, O'Connor, Mark J
Published in Cancer research (Chicago, Ill.) (15.07.2019)
Published in Cancer research (Chicago, Ill.) (15.07.2019)
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Journal Article
Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability
Merchut-Maya, Joanna Maria, Bartek, Jiri, Bartkova, Jirina, Galanos, Panagiotis, Pantalone, Mattia Russel, Lee, MyungHee, Cui, Huanhuan L., Shilling, Patrick J., Brøchner, Christian Beltoft, Broholm, Helle, Maya-Mendoza, Apolinar, Söderberg-Naucler, Cecilia, Bartek, Jiri
Published in Cell death and differentiation (01.08.2022)
Published in Cell death and differentiation (01.08.2022)
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Journal Article
NAD+ regulates nucleotide metabolism and genomic DNA replication
Munk, Sebastian Howen Nesgaard, Merchut-Maya, Joanna Maria, Adelantado Rubio, Alba, Hall, Arnaldur, Pappas, George, Milletti, Giacomo, Lee, MyungHee, Johnsen, Lea Giørtz, Guldberg, Per, Bartek, Jiri, Maya-Mendoza, Apolinar
Published in Nature cell biology (2023)
Published in Nature cell biology (2023)
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Journal Article
SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability
Hjorth-Jensen, Kim, Maya-Mendoza, Apolinar, Dalgaard, Nanna, Sigurðsson, Jón O, Bartek, Jiri, Iglesias-Gato, Diego, Olsen, Jesper V, Flores-Morales, Amilcar
Published in Nucleic acids research (12.10.2018)
Published in Nucleic acids research (12.10.2018)
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Journal Article
The human nucleoporin Tpr protects cells from RNA-mediated replication stress
Kosar, Martin, Giannattasio, Michele, Piccini, Daniele, Maya-Mendoza, Apolinar, García-Benítez, Francisco, Bartkova, Jirina, Barroso, Sonia I., Gaillard, Hélène, Martini, Emanuele, Restuccia, Umberto, Ramirez-Otero, Miguel Angel, Garre, Massimiliano, Verga, Eleonora, Andújar-Sánchez, Miguel, Maynard, Scott, Hodny, Zdenek, Costanzo, Vincenzo, Kumar, Amit, Bachi, Angela, Aguilera, Andrés, Bartek, Jiri, Foiani, Marco
Published in Nature communications (24.06.2021)
Published in Nature communications (24.06.2021)
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Journal Article