Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors
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Published in Journal of medicinal chemistry (28.06.2012)
Published in Journal of medicinal chemistry (28.06.2012)
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Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
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Published in Journal of medicinal chemistry (12.07.2012)
Published in Journal of medicinal chemistry (12.07.2012)
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Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1
Hurley, Christopher A., Blair, Wade S., Bull, Richard J., Chang, Christine, Crackett, Peter H., Deshmukh, Gauri, Dyke, Hazel J., Fong, Rina, Ghilardi, Nico, Gibbons, Paul, Hewitt, Peter R., Johnson, Adam, Johnson, Tony, Kenny, Jane R., Kohli, Pawan Bir, Kulagowski, Janusz J., Liimatta, Marya, Lupardus, Patrick J., Maxey, Robert J., Mendonca, Rohan, Narukulla, Raman, Pulk, Rebecca, Ubhayakar, Savita, van Abbema, Anne, Ward, Stuart I., Waszkowycz, Bohdan, Zak, Mark
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Published in Bioorganic & medicinal chemistry letters (15.06.2013)
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Methods development and implementation for the National Pesticide Survey
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Published in Environmental science & technology (01.10.1990)
Published in Environmental science & technology (01.10.1990)
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Year of Publication 17.06.2016
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Year of Publication 17.06.2016
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Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R., Braun, Matthew P., Cato, Brian P., Chambers, Mark S., O’Connor, Desmond, Cook, Susan M., Hobbs, Sarah C., Maxey, Robert, Szekeres, Helen J., Szeto, Nicola, Wafford, Keith A., MacLeod, Angus M.
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA(A) alpha5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R, Braun, Matthew P, Cato, Brian P, Chambers, Mark S, O'Connor, Desmond, Cook, Susan M, Hobbs, Sarah C, Maxey, Robert, Szekeres, Helen J, Szeto, Nicola, Wafford, Keith A, MacLeod, Angus M
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2- (1-methyl-1H-1,2,4-triazol-5-ylme thoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA sub(A) alpha 5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R, Braun, Matthew P, Cato, Brian P, Chambers, Mark S, O'Connor, Desmond, Cook, Susan M, Hobbs, Sarah C, Maxey, Robert, Szekeres, Helen J, Szeto, Nicola, Wafford, Keith A, MacLeod, Angus M
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Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Pharmacokinetics and metabolism studies on (3- tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1 H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5- d][1,2,4]triazine, a functionally selective GABA A α5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R., Braun, Matthew P., Cato, Brian P., Chambers, Mark S., O’Connor, Desmond, Cook, Susan M., Hobbs, Sarah C., Maxey, Robert, Szekeres, Helen J., Szeto, Nicola, Wafford, Keith A., MacLeod, Angus M.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Pharmacokinetics and metabolism studies on 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction
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Published in Bioorganic & medicinal chemistry letters (2006)
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BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes
Tudhope, Stephen R., Cuthbert, Nigel J., Abram, Trevor S., Jennings, Michael A., Maxey, Robert J., Thompson, Angela M., Norman, Peter, Gardiner, Phillip J.
Published in European journal of pharmacology (03.11.1994)
Published in European journal of pharmacology (03.11.1994)
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8-Methoxyquinoline-5-carboxamides as PDE4 inhibitors: a potential treatment for asthma
Buckley, George M., Cooper, Nicola, Dyke, Hazel J., Galleway, Fiona P., Gowers, Lewis, Haughan, Alan F., Kendall, Hannah J., Lowe, Christopher, Maxey, Robert, Montana, John G., Naylor, Robert, Oxford, Janet, Peake, Joanna C., Picken, C.Louise, Runcie, Karen A., Sabin, Verity, Sharpe, Andrew, Warneck, Julie B.H.
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Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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3-(4-Piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1h-indoles as bioavailable h5-HT2A antagonists
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Published in Bioorganic & medicinal chemistry letters (18.12.2000)
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3-(4-Piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1 H-indoles as bioavailable h5-HT 2A antagonists
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Published in Bioorganic & medicinal chemistry letters (2000)
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7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma
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Published in Bioorganic & medicinal chemistry letters (18.09.2000)
Published in Bioorganic & medicinal chemistry letters (18.09.2000)
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Pyridazine derivatives as RORc modulators
Gobbi, Alberto, Bodil van Niel, Monique, Fauber, Benjamin, Hurley, Christopher, Hurst, David, Ward, Stuart, Maxey, Robert, Killen, Jonathan, Cridland, Andrew
Year of Publication 29.05.2018
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Year of Publication 29.05.2018
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Aryl sulfonamides as selective PDE4 inhibitors
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Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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5,6,7,8-TETRAHYDRO-5,8-METHANOCINNOLINE DERIVATIVES AS RORC MODULATORS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
KILLEN, Jonathan, BODIL VAN NIEL, Monique, GOBBI, Alberto, HURLEY, Christopher, WARD, Stuart, FAUBER, Benjamin, HURST, David, CRIDLAND, Andrew, MAXEY, Robert
Year of Publication 20.12.2017
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Year of Publication 20.12.2017
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5,6,7,8-TETRAHYDRO-5,8-METHANOCINNOLINE DERIVATIVES AS RORC MODULATORS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
HURLEY, CHRISTOPHER, FAUBER, BENJAMIN, CRIDLAND, ANDREW, MAXEY, ROBERT, KILLEN, JONATHAN, WARD, STUART, BODIL VAN NIEL, MONIQUE, GOBBI, ALBERTO, HURST, DAVID
Year of Publication 14.09.2016
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Year of Publication 14.09.2016
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