3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D4 Receptor
Kulagowski, Janusz J, Broughton, Howard B, Curtis, Neil R, Mawer, Ian M, Ridgill, Mark P, Baker, Raymond, Emms, Frances, Freedman, Stephen B, Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Leeson, Paul D
Published in Journal of medicinal chemistry (10.05.1996)
Published in Journal of medicinal chemistry (10.05.1996)
Get full text
Journal Article
3'-(Arylmethyl)- and 3'-(Aryloxy)-3-phenyl-4-hydroxyquinolin- 2(1H)-ones: Orally Active Antagonists of the Glycine Site on the NMDA Receptor
Kulagowski, Janusz J, Baker, Raymond, Curtis, Neil R, Mawer, Ian M, Moseley, Angela M, Ridgill, Mark P, Rowley, Michael, Stansfield, Ian, Leeson, Paul D
Published in Journal of medicinal chemistry (01.05.1994)
Published in Journal of medicinal chemistry (01.05.1994)
Get full text
Journal Article
3-Nitro-3,4-dihydro-2(1H)-quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-.alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors
Carling, Robert W, Leeson, Paul D, Moore, Kevin W, Smith, Julian D, Moyes, Christopher R, Mawer, Ian M, Thomas, Steven, Chan, Tony, Baker, Raymond
Published in Journal of medicinal chemistry (01.10.1993)
Published in Journal of medicinal chemistry (01.10.1993)
Get full text
Journal Article
Amino acid bioisosteres: design of 2-quinolone derivatives as glycine-site N-methyl-D-aspartate receptor antagonists
Leeson, Paul D., Baker, Raymond, Carling, Robert W., Kulagowski, Janusz J., Mawer, Ian M., Ridgill, Mark P., Rowley, Michael, Smith, Julian D., Stansfield, Ian, Stevenson, Graeme I., Foster, Alan C., Kemp, John A.
Published in Bioorganic & medicinal chemistry letters (01.02.1993)
Published in Bioorganic & medicinal chemistry letters (01.02.1993)
Get full text
Journal Article
3-Nitro-3,4-dihydro-2(1H)quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors
CARLING, R. W, LEESON, P. D, GRIMWOOD, S, KEMP, J. A, MARSHALL, G. R, TRICKLEBANK, M. D, SAYWELL, K. L, MOORE, K. W, SMITH, J. D, MOYES, C. R, MAWER, I. M, THOMAS, S, CHAN, T, BAKER, R, FOSTER, A. C
Published in Journal of medicinal chemistry (29.10.1993)
Published in Journal of medicinal chemistry (29.10.1993)
Get full text
Journal Article
Tetramic acids as novel glycine site antagonists
Mawer, Ian M., Kulagowski, Janusz J., Leeson, Paul D., Grimwood, Sarah, Marshall, George R.
Published in Bioorganic & medicinal chemistry letters (16.11.1995)
Published in Bioorganic & medicinal chemistry letters (16.11.1995)
Get full text
Journal Article
3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1 H -pyrrolo[2,3- b ]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D 4 Receptor
Kulagowski, Janusz J., Broughton, Howard B., Curtis, Neil R., Mawer, Ian M., Ridgill, Mark P., Baker, Raymond, Emms, Frances, Freedman, Stephen B., Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Leeson, Paul D.
Published in Journal of medicinal chemistry (01.01.1996)
Published in Journal of medicinal chemistry (01.01.1996)
Get full text
Journal Article
Synthesis and SAR of diiodotyrosine-derived glycine-site N-methyl- D-aspartate receptor ligands
Curtis, Neil R., Kulagowski, Janusz J., Leeson, Paul D., Mawer, Ian M., Ridgill, Mark P., Rowley, Michael, Grimwood, Sarah, Marshall, George R.
Published in Bioorganic & medicinal chemistry letters (21.05.1996)
Published in Bioorganic & medicinal chemistry letters (21.05.1996)
Get full text
Journal Article
Indole derivatives as dopamine D4 antagonists
BAKER; RAYMOND, LEESON; PAUL D, BROUGHTON; HOWARD B, MAWER; IAN M, KULAGOWSKI; JANUSZ J
Year of Publication 19.11.1996
Get full text
Year of Publication 19.11.1996
Patent
Allosteric modulation of the glutamate site on the NMDA receptor by four novel glycine site antagonists
Grimwood, Sarah, Kulagowski, Janusz J., Mawer, Ian M., Rowley, Michael, Leeson, Paul D., Foster, Alan C.
Published in European journal of pharmacology. Molecular pharmacology section (01.01.1995)
Published in European journal of pharmacology. Molecular pharmacology section (01.01.1995)
Get full text
Journal Article