Role of Rad51 and DNA repair in cancer: A molecular perspective
Laurini, Erik, Marson, Domenico, Fermeglia, Alice, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Published in Pharmacology & therapeutics (Oxford) (01.04.2020)
Published in Pharmacology & therapeutics (Oxford) (01.04.2020)
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Journal Article
Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance
Wei, Tuo, Chen, Chao, Liu, Juan, Liu, Cheng, Posocco, Paola, Liu, Xiaoxuan, Cheng, Qiang, Huo, Shuaidong, Liang, Zicai, Fermeglia, Maurizio, Pricl, Sabrina, Liang, Xing-Jie, Rocchi, Palma, Peng, Ling
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2015)
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Journal Article
Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing
Chen, Chao, Posocco, Paola, Liu, Xiaoxuan, Cheng, Qiang, Laurini, Erik, Zhou, Jiehua, Liu, Cheng, Wang, Yang, Tang, Jingjie, Col, Valentina Dal, Yu, Tianzhu, Giorgio, Suzanne, Fermeglia, Maurizio, Qu, Fanqi, Liang, Zicai, Rossi, John J., Liu, Minghua, Rocchi, Palma, Pricl, Sabrina, Peng, Ling
Published in Small (Weinheim an der Bergstrasse, Germany) (01.07.2016)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.07.2016)
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Journal Article
Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma
Pricl, Sabrina, Cortelazzi, Barbara, Dal Col, Valentina, Marson, Domenico, Laurini, Erik, Fermeglia, Maurizio, Licitra, Lisa, Pilotti, Silvana, Bossi, Paolo, Perrone, Federica
Published in Molecular oncology (01.02.2015)
Published in Molecular oncology (01.02.2015)
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Journal Article
Perceptions and Misconceptions in Molecular Recognition: Key Factors in Self-Assembling Multivalent (SAMul) Ligands/Polyanions Selectivity
Marson, Domenico, Laurini, Erik, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Published in Molecules (Basel, Switzerland) (24.02.2020)
Published in Molecules (Basel, Switzerland) (24.02.2020)
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Journal Article
Molecular dynamics reveal BCR-ABL1 polymutants as a unique mechanism of resistance to PAN-BCR-ABL1 kinase inhibitor therapy
Gibbons, Don L., Pricl, Sabrina, Posocco, Paola, Laurini, Erik, Fermeglia, Maurizio, Sun, Hanshi, Talpaz, Moshe, Donato, Nicholas, Quintas-Cardama, Alfonso
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2014)
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Journal Article
Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)
Brambilla, Lara, Genini, Davide, Laurini, Erik, Merulla, Jessica, Perez, Laurent, Fermeglia, Maurizio, Carbone, Giuseppina M., Pricl, Sabrina, Catapano, Carlo V.
Published in Molecular oncology (01.06.2015)
Published in Molecular oncology (01.06.2015)
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Journal Article
Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers
Marson, Domenico, Laurini, Erik, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Published in Pharmaceutics (18.07.2019)
Published in Pharmaceutics (18.07.2019)
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Journal Article
Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled in Silico-Experimental Studies. Part II: Self-Assembled siRNA Nanocarriers
Laurini, Erik, Marson, Domenico, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Published in Pharmaceutics (10.07.2019)
Published in Pharmaceutics (10.07.2019)
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Journal Article
Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates
Woodman, Scott E, Trent, Jonathan C, Stemke-Hale, Katherine, Lazar, Alexander J, Pricl, Sabrina, Pavan, Giovanni M, Fermeglia, Maurizio, Gopal, Y N Vashisht, Yang, Dan, Podoloff, Donald A, Ivan, Doina, Kim, Kevin B, Papadopoulos, Nicholas, Hwu, Patrick, Mills, Gordon B, Davies, Michael A
Published in Molecular cancer therapeutics (01.08.2009)
Published in Molecular cancer therapeutics (01.08.2009)
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Journal Article
Structurally Flexible Triethanolamine Core PAMAM Dendrimers Are Effective Nanovectors for DNA Transfection in Vitro and in Vivo to the Mouse Thymus
Liu, Xiaoxuan, Wu, Jiangyu, Yammine, Miriam, Zhou, Jiehua, Posocco, Paola, Viel, Stephane, Liu, Cheng, Ziarelli, Fabio, Fermeglia, Maurizio, Pricl, Sabrina, Victorero, Genevieve, Nguyen, Catherine, Erbacher, Patrick, Behr, Jean-Paul, Peng, Ling
Published in Bioconjugate chemistry (21.12.2011)
Published in Bioconjugate chemistry (21.12.2011)
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Journal Article
Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands
Zampieri, Daniele, Vio, Luciano, Fermeglia, Maurizio, Pricl, Sabrina, Wünsch, Bernhard, Schepmann, Dirk, Romano, Maurizio, Mamolo, Maria Grazia, Laurini, Erik
Published in European journal of medicinal chemistry (04.10.2016)
Published in European journal of medicinal chemistry (04.10.2016)
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Journal Article
Another Brick in the Wall. Validation of the σ1 Receptor 3D Model by Computer-Assisted Design, Synthesis, and Activity of New σ1 Ligands
Laurini, Erik, Marson, Domenico, Dal Col, Valentina, Fermeglia, Maurizio, Mamolo, Maria Grazia, Zampieri, Daniele, Vio, Luciano, Pricl, Sabrina
Published in Molecular pharmaceutics (05.11.2012)
Published in Molecular pharmaceutics (05.11.2012)
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Journal Article
Self-assembling Nanotechnology for Cancer Personalized Medicine
Domenico Marson, Erik Laurini, Suzana Aulic, Maurizio Fermeglia, Sabrina Pricl
Published in Chemical engineering transactions (01.05.2019)
Published in Chemical engineering transactions (01.05.2019)
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Journal Article
Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives
TONELLI, Michele, VAZZANA, Iana, IBBA, Cristina, SECCI, Barbara, COLLU, Gabriella, LODDO, Roberta, TASSO, Bruno, BOIDO, Vito, SPARATORE, Fabio, FERMEGLIA, Maurizio, SILVIA PANENI, Maria, POSOCCO, Paola, PRICL, Sabrina, LA COLLA, Paolo
Published in Bioorganic & medicinal chemistry (01.07.2009)
Published in Bioorganic & medicinal chemistry (01.07.2009)
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Journal Article
Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-Scale synthesis, physicochemical characterization and in vitro metabolic stability
Rossi, Daniela, Marra, Annamaria, Picconi, Pietro, Serra, Massimo, Catenacci, Laura, Sorrenti, Milena, Laurini, Erik, Fermeglia, Maurizio, Pricl, Sabrina, Brambilla, Stefania, Almirante, Nicoletta, Peviani, Marco, Curti, Daniela, Collina, Simona
Published in Bioorganic & medicinal chemistry (01.05.2013)
Published in Bioorganic & medicinal chemistry (01.05.2013)
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Journal Article
Synthesis, Biological Evaluation, and Three-Dimensional in Silico Pharmacophore Model for σ1 Receptor Ligands Based on a Series of Substituted Benzo[d]oxazol-2(3H)-one Derivatives
Zampieri, Daniele, Mamolo, Maria Grazia, Laurini, Erik, Florio, Chiara, Zanette, Caterina, Fermeglia, Maurizio, Posocco, Paola, Paneni, Maria Silvia, Pricl, Sabrina, Vio, Luciano
Published in Journal of medicinal chemistry (10.09.2009)
Published in Journal of medicinal chemistry (10.09.2009)
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