Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases
Gardell, Jennifer L., Maurer, Meghan E., Childs, Monica M., Pham, Minh N., Meengs, Brent, Julien, Susan H., Tan, Cong, Boster, Daniel R., Quach, Phoenicia, Therriault, Jon H., Hermansky, Gleda, Patton, Daniel T., Bowser, Justin, Chen, Alex, Morgan, Nadine N., Gilbertson, Emily A., Bogatzki, Lisa, Encarnacion, Kaelen, McMahan, Catherine J., Crane, Courtney A., Swiderek, Kristine M.
Published in Frontiers in immunology (04.11.2024)
Published in Frontiers in immunology (04.11.2024)
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Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter
Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J
Published in The Journal of clinical investigation (01.08.2010)
Published in The Journal of clinical investigation (01.08.2010)
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Bispecific CD8 Treg modulators regulate a novel regulatory CD8 T cell network and eliminate pathogenic CD4 T cells in live cell co-culture system
Gardell, Jennifer L, Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Julien, Susan, Maurer, Meghan E, Templeton, Megan, Therriault, Jon, Yang, Su Jung, Swiderek, Kristine M
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article
Epigenetic downregulation of human disabled homolog 2 switches TGF-[Beta] from a tumor suppressor to a tumor promoter
Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J
Published in The Journal of clinical investigation (01.08.2010)
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Published in The Journal of clinical investigation (01.08.2010)
Journal Article