Search Results - "Matzkies, Franziska" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Integrated safety analysis of filgotinib treatment for rheumatoid arthritis in patients from Japan over a median of 1.5 years

Integrated safety analysis of filgotinib treatment for rheumatoid arthritis in patients from Japan over a median of 1.5 years

by Ishiguro, Naoki, Tanaka, Yoshiya, Matsubara, Tsukasa, Atsumi, Tatsuya, Amano, Koichi, Sugiyama, Eiji, Yamaoka, Kunihiro, Winthrop, Kevin, Kivitz, Alan, Burmester, Gerd R, Gottenberg, Jacques-Eric, Genovese, Mark C, Matzkies, Franziska, Guo, Ying, Jiang, Deyuan, Bartok, Beatrix, Pechonkina, Alena, Kondo, Akira, Besuyen, Robin, Takeuchi, Tsutomu
Published in Modern rheumatology (03.01.2023)

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Efficacy and safety of filgotinib in combination with methotrexate in Japanese patients with active rheumatoid arthritis who have an inadequate response to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 1)

Efficacy and safety of filgotinib in combination with methotrexate in Japanese patients with active rheumatoid arthritis who have an inadequate response to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 1)

by Tanaka, Yoshiya, Matsubara, Tsukasa, Atsumi, Tatsuya, Amano, Koichi, Ishiguro, Naoki, Sugiyama, Eiji, Yamaoka, Kunihiro, Combe, Bernard G, Kivitz, Alan J, Bae, Sang-Cheol, Keystone, Edward C, Nash, Peter, Matzkies, Franziska, Bartok, Beatrix, Pechonkina, Alena, Kondo, Akira, Ye, Lei, Guo, Ying, Tasset, Chantal, Sundy, John S, Takeuchi, Tsutomu
Published in Modern rheumatology (28.02.2022)

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Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study

Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study

by Matzkies, Franziska G, Targan, Stephan R, Berel, Dror, Landers, Carol J, Reveille, John D, McGovern, Dermot P B, Weisman, Michael H
Published in Arthritis research & therapy (29.11.2012)

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Characterization of the mechanism of action of lanraplenib, a novel spleen tyrosine kinase inhibitor, in models of lupus nephritis

Characterization of the mechanism of action of lanraplenib, a novel spleen tyrosine kinase inhibitor, in models of lupus nephritis

by Pohlmeyer, Christopher W, Shang, Ching, Han, Pei, Cui, Zhi-Hua, Jones, Randall M, Clarke, Astrid S, Murray, Bernard P, Lopez, David A, Newstrom, David W, Inzunza, M David, Matzkies, Franziska G, Currie, Kevin S, Di Paolo, Julie A
Published in BMC rheumatology (30.03.2021)

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$Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial$

Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial

by Genovese, Mark C, Kalunian, Kenneth, Gottenberg, Jacques-Eric, Mozaffarian, Neelufar, Bartok, Beatrix, Matzkies, Franziska, Gao, Jie, Guo, Ying, Tasset, Chantal, Sundy, John S, de Vlam, Kurt, Walker, David, Takeuchi, Tsutomu
Published in JAMA : the journal of the American Medical Association (23.07.2019)

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Filgotinib or lanraplenib in moderate to severe cutaneous lupus erythematosus: a phase 2, randomized, double-blind, placebo-controlled study

Filgotinib or lanraplenib in moderate to severe cutaneous lupus erythematosus: a phase 2, randomized, double-blind, placebo-controlled study

by Werth, Victoria P, Fleischmann, Roy, Robern, Michael, Touma, Zahi, Tiamiyu, Iyabode, Gurtovaya, Oksana, Pechonkina, Alena, Mozaffarian, Afsaneh, Downie, Bryan, Matzkies, Franziska, Wallace, Daniel
Published in Rheumatology (Oxford, England) (30.05.2022)

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Safety and efficacy of filgotinib, lanraplenib and tirabrutinib in Sjögren's syndrome: a randomized, phase 2, double-blind, placebo-controlled study

Safety and efficacy of filgotinib, lanraplenib and tirabrutinib in Sjögren's syndrome: a randomized, phase 2, double-blind, placebo-controlled study

by Price, Elizabeth, Bombardieri, Michele, Kivitz, Alan, Matzkies, Franziska, Gurtovaya, Oksana, Pechonkina, Alena, Jiang, Wendy, Downie, Bryan, Mathur, Anubhav, Mozaffarian, Afsaneh, Mozaffarian, Neelufar, Gottenberg, J Eric
Published in Rheumatology (Oxford, England) (28.11.2022)

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CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas

CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas

by Hueber, Axel J, Matzkies, Franziska G, Rahmeh, Martina, Manger, Bernhard, Kalden, Joachim R, Nagel, Thomas
Published in Immunology and cell biology (01.02.2006)

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Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial

Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial

by Combe, Bernard, Kivitz, Alan, Tanaka, Yoshiya, van der Heijde, Désirée, Simon, J Abraham, Baraf, Herbert S B, Kumar, Uma, Matzkies, Franziska, Bartok, Beatrix, Ye, Lei, Guo, Ying, Tasset, Chantal, Sundy, John S, Jahreis, Angelika, Genovese, Mark C, Mozaffarian, Neelufar, Landewé, Robert B M, Bae, Sang-Cheol, Keystone, Edward C, Nash, Peter
Published in Annals of the rheumatic diseases (01.07.2021)

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Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years

Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years

by Winthrop, Kevin L, Tanaka, Yoshiya, Takeuchi, Tsutomu, Kivitz, Alan, Matzkies, Franziska, Genovese, Mark C, Jiang, Deyuan, Chen, Kun, Bartok, Beatrix, Jahreis, Angelika, Besuyen, Robin, Burmester, Gerd R, Gottenberg, Jacques-Eric
Published in Annals of the rheumatic diseases (01.02.2022)

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Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial

Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial

by Westhovens, René, Rigby, William F C, van der Heijde, Désirée, Ching, Daniel W T, Stohl, William, Kay, Jonathan, Chopra, Arvind, Bartok, Beatrix, Matzkies, Franziska, Yin, Zhaoyu, Guo, Ying, Tasset, Chantal, Sundy, John S, Jahreis, Angelika, Mozaffarian, Neelufar, Messina, Osvaldo Daniel, Landewé, Robert BM, Atsumi, Tatsuya, Burmester, Gerd R
Published in Annals of the rheumatic diseases (01.06.2021)

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Semi‐Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA

Semi‐Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA

by Meng, Amy, Humeniuk, Rita, Jürgensmeier, Juliane M., Hsueh, Chia‐Hsiang, Matzkies, Franziska, Grant, Ethan, Truong, Hoa, Billin, Andrew N., Yu, Helen, Feng, Joy, Kwan, Ellen, Tarnowski, Thomas, Nelson, Cara H.
Published in Clinical pharmacology and therapeutics (01.02.2022)

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Su1862 POOLED SAFETY ANALYSES FROM PHASE 3 STUDIES OF FILGOTINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS

Su1862 POOLED SAFETY ANALYSES FROM PHASE 3 STUDIES OF FILGOTINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS

by Bartok, Beatrix, Winthrop, Kevin L., Genovese, Mark, Combe, Bernard G., Tanaka, Yoshiya, Kivitz, Alan, Matzkies, Franziska, Ye, Lei, Guo, Ying, Tasset, Chantal T., Sundy, John S., Keystone, Edward, Westhovens, Rene, Rigby, William, Burmester, Gerd R., Walker, David R.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)

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P210 Efficacy and safety of filgotinib for patients with RA with inadequate response to methotrexate: FINCH1 primary outcome results

P210 Efficacy and safety of filgotinib for patients with RA with inadequate response to methotrexate: FINCH1 primary outcome results

by Walker, David, Combe, Bernard G, Kivitiz, Alan J, Tanaka, Yoshiya, van der Heijde, Désirée, Matzkies, Franziska, Bartok, Beatrix, Ye, Lie, Guo, Ying, Tasset, Chantal, Sundy, John S, Mozaffarian, Neelufar, Landewé, Robert B. M, Bae, Sang-Cheol, Keystone, Edward C, Nash, Peter
Published in Rheumatology (Oxford, England) (01.04.2020)

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O09 Pooled safety analyses from Phase 3 studies of filgotinib in patients with RA

O09 Pooled safety analyses from Phase 3 studies of filgotinib in patients with RA

by Walker, David, Winthrop, Kevin, Genovese, Mark C, Combe, Bernard G, Tanaka, Yoshiya, Kivitiz, Alan, Matzkies, Franziska, Bartok, Beatrix, Ye, Lie, Guo, Ying, Tasset, Chantal, Sundy, John S, Keystone, Edward, Westhovens, Rene, Rigby, William, Burmester, Gerd R
Published in Rheumatology (Oxford, England) (01.04.2020)

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P133 Filgotinib in patients with RA with inadequate response to methotrexate: FINCH 1 52-week efficacy and patient reported outcomes data

P133 Filgotinib in patients with RA with inadequate response to methotrexate: FINCH 1 52-week efficacy and patient reported outcomes data

by Walker, David, Kivitz, Alan, Tanaka, Yoshiya, Lee, Susan, Ye, Lei, Hu, Hao, Matzkies, Franziska, Bartok, Beatrix, Guo, Ying, Sundy, John S, Jahreis, Angelika, Besuyen, Robin, Combe, Bernard, van der Heijde, Désirée, Simon-Campos, J-Abraham, Baraf, Herbert S B, Kumar, Uma, Tasset, Chantal, Mozaffarian, Neelufar, Landewé, Robert B M, Bae, Sang-Cheol, Keystone, Edward, Nash, Peter
Published in Rheumatology (Oxford, England) (25.04.2021)

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Safety and efficacy of filgotinib for Japanese patients with RA and inadequate response to MTX: FINCH 1 52-week results and FINCH 4 48-week results

Safety and efficacy of filgotinib for Japanese patients with RA and inadequate response to MTX: FINCH 1 52-week results and FINCH 4 48-week results

by Tanaka, Yoshiya, Matsubara, Tsukasa, Atsumi, Tatsuya, Amano, Koichi, Ishiguro, Naoki, Sugiyama, Eiji, Yamaoka, Kunihiro, Combe, Bernard G, Kivitz, Alan J, Bae, Sang-Cheol, Keystone, Edward C, Nash, Peter, Genovese, Mark, Matzkies, Franziska, Bartok, Beatrix, Pechonkina, Alena, Kondo, Akira, Ye, Lei, Gong, Qi, Tasset, Chantal, Takeuchi, Tsutomu
Published in Modern rheumatology (04.07.2023)

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Effects of GS-9876, a novel spleen tyrosine kinase inhibitor, on platelet function and systemic hemostasis

Effects of GS-9876, a novel spleen tyrosine kinase inhibitor, on platelet function and systemic hemostasis

by Clarke, Astrid S., Rousseau, Emma, Wang, Kelly, Kim, Ji-Yun, Murray, Bernard P., Bannister, Roy, Matzkies, Franziska, Currie, Kevin S., Di Paolo, Julie A.
Published in Thrombosis research (01.10.2018)

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086 Safety and efficacy of filgotinib in a phase 3 trial of patients with active rheumatoid arthritis and inadequate response or intolerance to biologic disease modifying anti-rheumatic drugs

086 Safety and efficacy of filgotinib in a phase 3 trial of patients with active rheumatoid arthritis and inadequate response or intolerance to biologic disease modifying anti-rheumatic drugs

by Walker, David, Genovese, Mark C, Kalunian, Kenneth, Gottenberg, Jacques-Eric, de Vlam, Kurt, Mozaffarian, Neelufar, Bartok, Beatrix, Matzkies, Franziska, Gao, Jie, Guo, Ying, Tasset, Chantal, Sundy, John S, Takeuchi, Tsutomu
Published in Rheumatology (Oxford, England) (01.04.2019)

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P217 Efficacy and safety of filgotinib for patients with RA naïve to MTX therapy: FINCH3 primary outcome results

P217 Efficacy and safety of filgotinib for patients with RA naïve to MTX therapy: FINCH3 primary outcome results

by McKay, Neil, van der Heijde, Désirée, Westhovens, Rene, Rigby, William F. C, Ching, Daniel W. T, Bartok, Beatrix, Matzkies, Franziska, Yin, Zhaoyu, Guo, Ying, Tasset, Chantal, Sundy, John S, Mozaffarian, Neelufar, Messina, Osvaldo D, Landewé, Robert B. M, Atsumi, Tatsuya, Burmester, Gerd R
Published in Rheumatology (Oxford, England) (01.04.2020)

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