Panobinostat penetrates the blood–brain barrier and achieves effective brain concentrations in a murine model
Homan, Morgan J., Franson, Andrea, Ravi, Karthik, Roberts, Holly, Pai, Manjunath P., Liu, Cai, He, Miao, Matvekas, Aleksas, Koschmann, Carl, Marini, Bernard L.
Published in Cancer chemotherapy and pharmacology (01.09.2021)
Published in Cancer chemotherapy and pharmacology (01.09.2021)
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Journal Article
Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes
Moody, Rebecca Reed, Lo, Miao-Chia, Meagher, Jennifer L., Lin, Chang-Ching, Stevers, Nicholas O., Tinsley, Samantha L., Jung, Inkyung, Matvekas, Aleksas, Stuckey, Jeanne A., Sun, Duxin
Published in The Journal of biological chemistry (09.02.2018)
Published in The Journal of biological chemistry (09.02.2018)
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Journal Article
Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer
Han, Xin, Zhao, Lijie, Xiang, Weiguo, Qin, Chong, Miao, Bukeyan, McEachern, Donna, Wang, Yu, Metwally, Hoda, Wang, Lu, Matvekas, Aleksas, Wen, Bo, Sun, Duxin, Wang, Shaomeng
Published in Journal of medicinal chemistry (09.09.2021)
Published in Journal of medicinal chemistry (09.09.2021)
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Journal Article
Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
Xiang, Weiguo, Zhao, Lijie, Han, Xin, Qin, Chong, Miao, Bukeyan, McEachern, Donna, Wang, Yu, Metwally, Hoda, Kirchhoff, Paul D, Wang, Lu, Matvekas, Aleksas, He, Miao, Wen, Bo, Sun, Duxin, Wang, Shaomeng
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Journal Article
Alteration in Acute Kidney Injury Potential with the Combination of Vancomycin and Imipenem-Cilastatin/Relebactam or Piperacillin/Tazobactam in a Preclinical Model
He, Miao, Souza, Ernane, Matvekas, Aleksas, Crass, Ryan L, Pai, Manjunath P
Published in Antimicrobial agents and chemotherapy (18.03.2021)
Published in Antimicrobial agents and chemotherapy (18.03.2021)
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Journal Article
Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer
Chen, Zhixiang, Wang, Mi, Wu, Dimin, Zhao, Lijie, Metwally, Hoda, Jiang, Wei, Wang, Yu, Bai, Longchuan, McEachern, Donna, Luo, Jie, Wang, Meilin, Li, Qiuxia, Matvekas, Aleksas, Wen, Bo, Sun, Duxin, Chinnaiyan, Arul M., Wang, Shaomeng
Published in Journal of medicinal chemistry (11.04.2024)
Published in Journal of medicinal chemistry (11.04.2024)
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Sa1209 GASTROINTESTINAL INTUBATION USING A MULTI-PORT ASPIRATION CATHETER TO STUDY DRUG RELEASE OF EXTENDED-RELEASE GLIPIZIDE DRUG PRODUCTS IN THE GASTROINTESTINAL TRACT OF HEALTHY HUMANS
Abdelnabi, Mohamed, Watts, Lydia, Singh, Prashant, Li, Ruiting, Lkhagva, Ankhbayar, Duan, Shengnan, Liu, Shuhan, Wen, Bo, Baker, Jason, Matvekas, Aleksas, Chey, William D., Hasler, William L., Raofi, Saeid, Sun, Wei-Jhe, Boyce, Heather, Kinjo, Minori, Pai, Manjunath, Sun, Duxin, Nojkov, Borko
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
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Journal Article
Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
Han, Xin, Zhao, Lijie, Xiang, Weiguo, Miao, Bukeyan, Qin, Chong, Wang, Mi, Xu, Tianfeng, McEachern, Donna, Lu, Jianfeng, Wang, Yu, Metwally, Hoda, Yang, Chao-Yie, Kirchhoff, Paul D., Wang, Lu, Matvekas, Aleksas, Takyi-Williams, John, Wen, Bo, Sun, Duxin, Ator, Mark, Mckean, Robert, Wang, Shaomeng
Published in Journal of medicinal chemistry (13.07.2023)
Published in Journal of medicinal chemistry (13.07.2023)
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Journal Article
Morphomics‐informed population pharmacokinetic and physiologically‐based pharmacokinetic modeling to optimize cefazolin surgical prophylaxis
Liu, Shuhan, Matvekas, Aleksas, Naimi, Tamara, Ghanem, Aws, Li, Ruiting, Rajanayake, Krishani, Derstine, Brian, Ross, Brian, Sullivan, June, Yun, Hyun Gi, Regenbogen, Scott, Byrn, John, Su, Grace, Wang, Stewart, Pai, Manjunath P.
Published in Pharmacotherapy (01.01.2024)
Published in Pharmacotherapy (01.01.2024)
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Journal Article
2555. Metronidazole Dosing in Patients with and without Obesity Undergoing Colorectal Surgery: Should body size or composition be a factor?
Pai, Manjunath P, Matvekas, Aleksas, Rajanayake, Krishani, Carrier, Theresa, Nguyen, Allison, Ross, Brian, Sullivan, June, Alikhani, Radin, Abdelnabi, Mohamed, Regenbogen, Scott, Byrn, John, Su, Grace, Wang, Stewart
Published in Open forum infectious diseases (27.11.2023)
Published in Open forum infectious diseases (27.11.2023)
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Journal Article
Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes
Moody, Rebecca Reed, Lo, Miao-Chia, Meagher, Jennifer L., Lin, Chang-Ching, Stevers, Nicholas O., Tinsley, Samantha L., Jung, Inkyung, Matvekas, Aleksas, Stuckey, Jeanne A., Sun, Duxin
Published in The Journal of biological chemistry (01.02.2018)
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Published in The Journal of biological chemistry (01.02.2018)
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