How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization
Brock, Ethan J, Ji, Kyungmin, Reiners, John J, Mattingly, Raymond R
Published in Mini reviews in medicinal chemistry (01.01.2016)
Published in Mini reviews in medicinal chemistry (01.01.2016)
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Journal Article
Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration
Osuala, Kingsley O, Sameni, Mansoureh, Shah, Seema, Aggarwal, Neha, Simonait, Michelle L, Franco, Omar E, Hong, Yan, Hayward, Simon W, Behbod, Fariba, Mattingly, Raymond R, Sloane, Bonnie F
Published in BMC cancer (13.08.2015)
Published in BMC cancer (13.08.2015)
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Journal Article
Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation
Shah, Seema, Brock, Ethan J., Jackson, Ryan M., Ji, Kyungmin, Boerner, Julie L., Sloane, Bonnie F., Mattingly, Raymond R.
Published in Neoplasia (New York, N.Y.) (01.09.2018)
Published in Neoplasia (New York, N.Y.) (01.09.2018)
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Journal Article
Acid-Mediated Tumor Proteolysis: Contribution of Cysteine Cathepsins
Rothberg, Jennifer M, Bailey, Kate M, Wojtkowiak, Jonathan W, Ben-Nun, Yael, Bogyo, Matthew, Weber, Ekkehard, Moin, Kamiar, Blum, Galia, Mattingly, Raymond R, Gillies, Robert J, Sloane, Bonnie F
Published in Neoplasia (New York, N.Y.) (01.10.2013)
Published in Neoplasia (New York, N.Y.) (01.10.2013)
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Journal Article
Sprouty4 negatively regulates ERK/MAPK signaling and the transition from in situ to invasive breast ductal carcinoma
Brock, Ethan J, Jackson, Ryan M, Boerner, Julie L, Li, Quanwen, Tennis, Meredith A, Sloane, Bonnie F, Mattingly, Raymond R
Published in PloS one (28.05.2021)
Published in PloS one (28.05.2021)
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Journal Article
Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ
Sameni, Mansoureh, Cavallo-Medved, Dora, Franco, Omar E, Chalasani, Anita, Ji, Kyungmin, Aggarwal, Neha, Anbalagan, Arulselvi, Chen, Xuequn, Mattingly, Raymond R, Hayward, Simon W, Sloane, Bonnie F
Published in Breast cancer research : BCR (15.05.2017)
Published in Breast cancer research : BCR (15.05.2017)
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The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes
Kanaan, Nicholas M, Collier, Timothy J, Cole-Strauss, Allyson, Grabinski, Tessa, Mattingly, Zachary R, Winn, Mary E, Steece-Collier, Kathy, Sortwell, Caryl E, Manfredsson, Fredric P, Lipton, Jack W
Published in PloS one (20.05.2015)
Published in PloS one (20.05.2015)
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Journal Article
Tyrosyl Phosphorylated PAK1 Regulates Breast Cancer Cell Motility in Response to Prolactin through Filamin A
Hammer, Alan, Rider, Leah, Oladimeji, Peter, Cook, Leslie, Li, Quanwen, Mattingly, Raymond R, Diakonova, Maria
Published in Molecular endocrinology (Baltimore, Md.) (01.03.2013)
Published in Molecular endocrinology (Baltimore, Md.) (01.03.2013)
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Journal Article
Ang II acutely stimulates Na,K‐pump in cells from proximal tubules by increasing its phosphorylation at S938 via a PI3K/AKT pathway
Hanna, Fadia S., Alkhouri, Samaa, Rajagopalan, Carthic, Ji, Kyungmin, Mattingly, Raymond R., Yingst, Douglas R.
Published in Physiological reports (01.11.2022)
Published in Physiological reports (01.11.2022)
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Journal Article
Pak and Rac GTPases promote oncogenic KIT-induced neoplasms
Martin, Holly, Mali, Raghuveer Singh, Ma, Peilin, Chatterjee, Anindya, Ramdas, Baskar, Sims, Emily, Munugalavadla, Veerendra, Ghosh, Joydeep, Mattingly, Ray R, Visconte, Valeria, Tiu, Ramon V, Vlaar, Cornelis P, Dharmawardhane, Suranganie, Kapur, Reuben
Published in The Journal of clinical investigation (01.10.2013)
Published in The Journal of clinical investigation (01.10.2013)
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Journal Article
RNA-Seq of human breast ductal carcinoma in situ models reveals aldehyde dehydrogenase isoform 5A1 as a novel potential target
Kaur, Hitchintan, Mao, Shihong, Li, Quanwen, Sameni, Mansoureh, Krawetz, Stephen A, Sloane, Bonnie F, Mattingly, Raymond R
Published in PloS one (06.12.2012)
Published in PloS one (06.12.2012)
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Journal Article
p21-Activated Kinase 1 Coordinates Aberrant Cell Survival and Pericellular Proteolysis in a Three-Dimensional Culture Model for Premalignant Progression of Human Breast Cancer
Li, Quanwen, Mullins, Stefanie Roshy, Sloane, Bonnie F., Mattingly, Raymond R.
Published in Neoplasia (New York, N.Y.) (01.04.2008)
Published in Neoplasia (New York, N.Y.) (01.04.2008)
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Journal Article
Ras and Rap1: A tale of two GTPases
Shah, Seema, Brock, Ethan J., Ji, Kyungmin, Mattingly, Raymond R.
Published in Seminars in cancer biology (01.02.2019)
Published in Seminars in cancer biology (01.02.2019)
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Journal Article
High RhoA Activity Maintains the Undifferentiated Mesenchymal Cell Phenotype, Whereas RhoA Down-Regulation by Laminin-2 Induces Smooth Muscle Myogenesis
Beqaj, Safedin, Jakkaraju, Sandhya, Mattingly, Raymond R., Pan, Desi, Schuger, Lucia
Published in The Journal of cell biology (04.03.2002)
Published in The Journal of cell biology (04.03.2002)
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Journal Article
The Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibitor PD184352 (CI-1040) Selectively Induces Apoptosis in Malignant Schwannoma Cell Lines
Mattingly, Raymond R, Kraniak, Janice M, Dilworth, Joshua T, Mathieu, Patricia, Bealmear, Beverly, Nowak, James E, Benjamins, Joyce A, Tainsky, Michael A, Reiners, Jr, John J
Published in The Journal of pharmacology and experimental therapeutics (01.01.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2006)
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Electrical stimulation of Schwann cells on electrospun hyaluronic acid carbon nanotube fibers
Senanayake, Judy, Mattingly, Raymond R, Sundararaghavan, Harini G
Published in PloS one (07.08.2024)
Published in PloS one (07.08.2024)
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Journal Article
Induction of Apoptosis in Neurofibromatosis Type 1 Malignant Peripheral Nerve Sheath Tumor Cell Lines by a Combination of Novel Farnesyl Transferase Inhibitors and Lovastatin
Wojtkowiak, Jonathan W, Fouad, Farid, LaLonde, Daniel T, Kleinman, Miriam D, Gibbs, Richard A, Reiners, Jr, John J, Borch, Richard F, Mattingly, Raymond R
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
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