Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses
Romain, Gabrielle, Strati, Paolo, Rezvan, Ali, Fathi, Mohsen, Bandey, Irfan N, Adolacion, Jay R.T, Heeke, Darren, Liadi, Ivan, Marques-Piubelli, Mario L, Solis, Luisa M, Mahendra, Ankit, Vega, Francisco, Cooper, Laurence J.N, Singh, Harjeet, Mattie, Mike, Bot, Adrian, Neelapu, Sattva S, Varadarajan, Navin
Published in The Journal of clinical investigation (01.09.2022)
Published in The Journal of clinical investigation (01.09.2022)
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EASIX and Severe Endothelial Complications After CD19-Directed CAR-T Cell Therapy-A Cohort Study
Korell, Felix, Penack, Olaf, Mattie, Mike, Schreck, Nicholas, Benner, Axel, Krzykalla, Julia, Wang, Zixing, Schmitt, Michael, Bullinger, Lars, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas
Published in Frontiers in immunology (08.04.2022)
Published in Frontiers in immunology (08.04.2022)
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IL-4 drives exhaustion of CD8+ CART cells
Stewart, Carli M., Siegler, Elizabeth L., Sakemura, R. Leo, Cox, Michelle J., Huynh, Truc, Kimball, Brooke, Mai, Long, Can, Ismail, Manriquez Roman, Claudia, Yun, Kun, Sirpilla, Olivia, Girsch, James H., Ogbodo, Ekene, Mohammed Ismail, Wazim, Gaspar-Maia, Alexandre, Budka, Justin, Kim, Jenny, Scholler, Nathalie, Mattie, Mike, Filosto, Simone, Kenderian, Saad S.
Published in Nature communications (12.09.2024)
Published in Nature communications (12.09.2024)
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Radiomic features of PET/CT imaging of large B cell lymphoma lesions predicts CAR T cell therapy efficacy
Balagurunathan, Yoganand, Wei, Zhouping, Qi, Jin, Thompson, Zachary, Dean, Erin, Lu, Hong, Vardhanabhuti, Saran, Corallo, Salvatore, Choi, Jung W., Kim, Jenny J., Mattie, Mike, Jain, Michael, Locke, Frederick L.
Published in Frontiers in oncology (25.11.2024)
Published in Frontiers in oncology (25.11.2024)
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CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production
Abraham-Miranda, Julieta, Menges, Meghan, Atkins, Reginald, Mattie, Mike, Kanska, Justyna, Turner, Joel, Hidalgo-Vargas, Melanie J., Locke, Frederick L.
Published in Frontiers in immunology (26.09.2022)
Published in Frontiers in immunology (26.09.2022)
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Molecular Characterization of Patient-Derived Human Pancreatic Tumor Xenograft Models for Preclinical and Translational Development of Cancer Therapeutics
Mattie, Mike, Christensen, Ashley, Chang, Mi Sook, Yeh, William, Said, Suzanne, Shostak, Yuriy, Capo, Linnette, Verlinsky, Alla, An, Zili, Joseph, Ingrid, Zhang, Yi, Kumar-Ganesan, Sathish, Morrison, Karen, Stover, David, Challita-Eid, Pia
Published in Neoplasia (New York, N.Y.) (01.10.2013)
Published in Neoplasia (New York, N.Y.) (01.10.2013)
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Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma
Scholler, Nathalie, Perbost, Regis, Locke, Frederick L., Jain, Michael D., Turcan, Sarah, Danan, Corinne, Chang, Edmund C., Neelapu, Sattva S., Miklos, David B., Jacobson, Caron A., Lekakis, Lazaros J., Lin, Yi, Ghobadi, Armin, Kim, Jenny J., Chou, Justin, Plaks, Vicki, Wang, Zixing, Xue, Allen, Mattie, Mike, Rossi, John M., Bot, Adrian, Galon, Jérôme
Published in Nature medicine (01.09.2022)
Published in Nature medicine (01.09.2022)
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Advancing CAR-T Therapy in Acute Lymphoblastic Leukemia: Multi-Omic Analyses of CD19-Directed CAR-T Cells Enabled By an Ex Vivo Co-Culture Platform
Mattie, Mike, Gillard, Marc, Calderon, Monica, Do, Sophia, Salunkhe, Shruti, Heeke, Darren, Morachis, Jose, Titz, Benjamin, Pak, Chorom
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Personal and Shared Tumor-Antigen Prioritization in Diffuse Large B Cell Lymphoma Patients Undergoing CD19 CAR T Cell Treatment
Karagkouni, Dimitra, Katopodi, Xanthi Lida, Cheloni, Giulia, Ma, Yuling, Miles, Brodie, Tiwari, Gayatri, Kim, Jenny J., Mattie, Mike, Rosenblatt, Jacalyn, Avigan, David, Vlachos, Ioannis
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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An Inflammatory Biomarker Signature Reproducibly Predicts CAR-T Treatment Failure in Patients with Aggressive Lymphoma across the Zuma Trials Cohorts
Raj, Sandeep, Xie, Jin, Fei, Teng, Song, Qinghua, Kim, Jenny J., To, Christina, van den Brink, Marcel R.M., Perales, Miguel-Angel, Mattie, Mike, Shouval, Roni
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Impact of tumor microenvironment on efficacy of anti-CD19 CAR T cell therapy or chemotherapy and transplant in large B cell lymphoma
Locke, Frederick L., Filosto, Simone, Chou, Justin, Vardhanabhuti, Saran, Perbost, Regis, Dreger, Peter, Hill, Brian T., Lee, Catherine, Zinzani, Pier L., Kröger, Nicolaus, López-Guillermo, Armando, Greinix, Hildegard, Zhang, Wangshu, Tiwari, Gayatri, Budka, Justin, Marincola, Francesco M., To, Christina, Mattie, Mike, Schupp, Marco, Cheng, Paul, Bot, Adrian, Shen, Rhine, Bedognetti, Davide, Miao, Harry, Galon, Jérôme
Published in Nature medicine (01.02.2024)
Published in Nature medicine (01.02.2024)
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Pre- and Post-Treatment Immune Contexture Correlates with Long Term Response in Large B Cell Lymphoma Patients Treated with Axicabtagene Ciloleucel (axi-cel)
Mattie, Mike, Grosso, Melanie, Auguste, Aurelie, Arnaud, Denis, Locke, Frederick L., Neelapu, Sattva S., Miklos, David B., Jacobson, Caron A, Lekakis, Lazaros J., Lin, Yi, Ghobadi, Armin, Kim, Jenny J., Nater, Jenny, Shen, Rhine R., Galon, Jerome
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Targeting CNS Lymphoma with Intravenous Axicabtagene Ciloleucel: Evidence for Transcriptional Evolution Towards a Prominent Interferon Signature in CAR-T Cells Trafficking to the Tumor Site
Gerdemann, Ulrike, Kaminski, James, Albanese, Alexandre, Keskula, Paula, Cagnin, Lorenzo, Betz, Kayla, Zavistaski, Jillian, Fleming, Ryan A, Falvey, Caroline, Bouvier, Riemke, Jones, Julia, Poddar, Soumya, Mattie, Mike, Chukwueke, Ugonma, Torres, Alexandra, Jacobson, Caron A., Nayak, Lakshmi, Kean, Leslie S.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Identification of IL-4 As a Key Regulator of CAR T-Cell Exhaustion Using Functional Genomics and Correlates of the Zuma-1 Clinical Trial
Stewart, Carli M., Cox, Michelle J., Sakemura, Reona Leo, Ogbodo, Ekene J., Can, Ismail, Manriquez-Roman, Claudia, Yun, Kun, Sirpilla, Olivia, Girsch, James H., Huynh, Truc, Siegler, Elizabeth L., Kim, Jenny J, Mattie, Mike, Scholler, Nathalie, Filosto, Simone, Kenderian, Saad S.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Durable Response to CD19 CAR T Cell Therapy Is Associated with Cytotoxicity and Clonotypic Expansion of the Native T Cell Repertoire
Cheloni, Giulia, Karagkouni, Dimitra, Pita-Juarez, Yered, Torres, Daniela, Kanata, Eleni, Avigan, Zachary M., Liegel, Jessica, Stroopinsky, Dina, Miles, Brodie, Tiwari, Gayatri, Kim, Jenny, Mattie, Mike, Rosenblatt, Jacalyn, Avigan, David, Vlachos, Ioannis
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Axicabtagene Ciloleucel in Combination With the 4-1BB Agonist Utomilumab in Patients With Relapsed/Refractory Large B-Cell Lymphoma: Phase 1 Results From ZUMA-11
Jain, Michael D, Miklos, David B, Jacobson, Caron A, Timmerman, John M, Sun, Jennifer, Nater, Jenny, Fang, Xiang, Patel, Ankit, Davis, Madison, Heeke, Darren, Trinh, Tan, Mattie, Mike, Neumann, Frank, Kim, Jenny J, To, Christina, Filosto, Simone, Reshef, Ran
Published in Clinical cancer research (13.10.2023)
Published in Clinical cancer research (13.10.2023)
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Baseline Immune State and T Cell Clonal Kinetics Are Associated with Response to CAR-T Therapy in Large B-Cell Lymphoma
Maurer, Katie, Grabski, Isabella N., Houot, Roch, Gohil, Satyen H, Miura, Shogo, Redd, Robert A., Lyu, Haoxiang, Lu, Wesley S, Miles, Brodie, Mattie, Mike, Arihara, Yohei, McDonough, Mikaela M., Reynolds, Carol, Ansuinelli, Michela, Li, Shuqiang, Livak, Kenneth J., Ritz, Jerome, Rodig, Scott, Irizarry, Rafael A., Armand, Philippe, Wu, Catherine J, Jacobson, Caron A.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Profiling the Peripheral Blood Immune Cell Repertoire in Large-B Cell Lymphoma Patients Treated with CD19 CAR-T
Cheloni, Giulia, Kanata, Eleni, Stroopinsky, Dina, Karagkouni, Dimitra, Liegel, Jessica J., Torres, Daniela, Hauser, Joshua, Bindal, Poorva, Koshy, Anita G., Pita-Juarez, Yered, Bot, Adrian, Mattie, Mike, Chou, Justin, Rosenblatt, Jacalyn, Avigan, David, Vlachos, Ioannis
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma
Maurer, Katie, Grabski, Isabella N., Houot, Roch, Gohil, Satyen H., Miura, Shogo, Redd, Robert, Lyu, Haoxiang, Lu, Wesley, Arihara, Yohei, Budka, Justin, McDonough, Mikaela, Ansuinelli, Michela, Reynolds, Carol, Jacene, Heather, Li, Shuqiang, Livak, Kenneth J., Ritz, Jerome, Miles, Brodie, Mattie, Mike, Neuberg, Donna S., Irizarry, Rafael A., Armand, Philippe, Wu, Catherine J., Jacobson, Caron
Published in Blood (06.09.2024)
Published in Blood (06.09.2024)
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Baseline CRP and Ferritin Identify Patients at High Risk of Poor Outcomes after Axicabtagene Ciloleucel Despite Corticosteroid Prophylaxis
Faramand, Rawan, Jain, Michael D., Cao, Biwei, Wang, Xuefeng, Reid, Kayla M., Lee, Sae Bom, Corallo, Salvatore A., Menges, Meghan A., Hidalgo-Vargas, Melanie, Bachmeier, Christina A., Chavez, Julio C., Shah, Bijal D., Pinilla Ibarz, Javier, Lazaryan, Aleksandr, Khimani, Farhad, Nishihori, Taiga, Speth, Kelly, Song, Qinghua, Mattie, Mike, Locke, Frederick L., Davila, Marco L.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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