Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST)
Burkholder, Nathaniel Tate, Mayfield, Joshua E., Yu, Xiaohua, Irani, Seema, Arce, Daniel K., Jiang, Faqin, Matthews, Wendy L., Xue, Yuanchao, Zhang, Yan Jessie
Published in The Journal of biological chemistry (26.10.2018)
Published in The Journal of biological chemistry (26.10.2018)
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Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells
Medellin, Brenda, Yang, Wanjie, Konduri, Srihari, Dong, Jiajun, Irani, Seema, Wu, Haoyi, Matthews, Wendy L, Zhang, Zhong-Yin, Siegel, Dionico, Zhang, Yan
Published in Journal of medicinal chemistry (13.01.2022)
Published in Journal of medicinal chemistry (13.01.2022)
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Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription
Irani, Seema, Sipe, Sarah N., Yang, Wanjie, Burkholder, Nathaniel T., Lin, Brian, Sim, Kelly, Matthews, Wendy L., Brodbelt, Jennifer S., Zhang, Yan
Published in The Journal of biological chemistry (24.05.2019)
Published in The Journal of biological chemistry (24.05.2019)
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Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase
Irani, Seema, Yogesha, S D, Mayfield, Joshua, Zhang, Mengmeng, Zhang, Yong, Matthews, Wendy L, Nie, Grace, Prescott, Nicholas A, Zhang, Yan Jessie
Published in Science signaling (01.03.2016)
Published in Science signaling (01.03.2016)
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Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass Spectrometry
Mayfield, Joshua E, Robinson, Michelle R, Cotham, Victoria C, Irani, Seema, Matthews, Wendy L, Ram, Anjana, Gilmour, David S, Cannon, Joe R, Zhang, Yan Jessie, Brodbelt, Jennifer S
Published in ACS chemical biology (20.01.2017)
Published in ACS chemical biology (20.01.2017)
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