Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal
Tettey, Mabel Deladem, Rojas, Federico, Matthews, Keith R.
Published in Nature communications (09.06.2022)
Published in Nature communications (09.06.2022)
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Journal Article
Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing
Briggs, Emma M., Rojas, Federico, McCulloch, Richard, Matthews, Keith R., Otto, Thomas D.
Published in Nature communications (06.09.2021)
Published in Nature communications (06.09.2021)
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Journal Article
Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing
Rojas, Federico, Silvester, Eleanor, Young, Julie, Milne, Rachel, Tettey, Mabel, Houston, Douglas R., Walkinshaw, Malcolm D., Pérez-Pi, Irene, Auer, Manfred, Denton, Helen, Smith, Terry K., Thompson, Joanne, Matthews, Keith R.
Published in Cell (10.01.2019)
Published in Cell (10.01.2019)
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Journal Article
A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development
Silvester, Eleanor, Ivens, Alasdair, Matthews, Keith R
Published in PLoS neglected tropical diseases (01.10.2018)
Published in PLoS neglected tropical diseases (01.10.2018)
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Journal Article
Differentiation granules, a dynamic regulator of T. brucei development
Cayla, Mathieu, Spanos, Christos, McWilliam, Kirsty, Waskett, Eliza, Rappsilber, Juri, Matthews, Keith R.
Published in Nature communications (06.04.2024)
Published in Nature communications (06.04.2024)
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Journal Article
Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts
Morrison, Liam J., Steketee, Pieter C., Tettey, Mabel D., Matthews, Keith R.
Published in Virulence (31.12.2023)
Published in Virulence (31.12.2023)
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Journal Article
A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense
Silvester, Eleanor, Szoor, Balazs, Ivens, Alasdair, Awuah-Mensah, Georgina, Gadelha, Catarina, Wickstead, Bill, Matthews, Keith R
Published in PLoS pathogens (01.02.2024)
Published in PLoS pathogens (01.02.2024)
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Journal Article
Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro
Rojas, Federico, Cayla, Mathieu, Matthews, Keith R
Published in PLoS neglected tropical diseases (28.04.2021)
Published in PLoS neglected tropical diseases (28.04.2021)
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Journal Article
African trypanosomes
Cayla, Mathieu, Rojas, Federico, Silvester, Eleanor, Venter, Frank, Matthews, Keith R
Published in Parasites & vectors (29.04.2019)
Published in Parasites & vectors (29.04.2019)
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Journal Article
Mechanisms of life cycle simplification in African trypanosomes
Oldrieve, Guy R., Venter, Frank, Cayla, Mathieu, Verney, Mylène, Hébert, Laurent, Geerts, Manon, Van Reet, Nick, Matthews, Keith R.
Published in Nature communications (02.12.2024)
Published in Nature communications (02.12.2024)
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Journal Article
Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act
MacGregor, Paula, Szöőr, Balazs, Savill, Nicholas J., Matthews, Keith R.
Published in Nature reviews. Microbiology (01.06.2012)
Published in Nature reviews. Microbiology (01.06.2012)
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Journal Article
Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle
Saldanha, Isabel, Betson, Martha, Vrettou, Christina, Paxton, Edith, Nixon, James, Tennant, Peter, Ritchie, Adrian, Matthews, Keith R., Morrison, Liam J., Torr, Stephen J., Cunningham, Lucas J.
Published in Scientific reports (20.02.2024)
Published in Scientific reports (20.02.2024)
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Journal Article
Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes
McDonald, Lindsay, Cayla, Mathieu, Ivens, Alasdair, Mony, Binny M, MacGregor, Paula, Silvester, Eleanor, McWilliam, Kirsty, Matthews, Keith R
Published in PLoS pathogens (01.06.2018)
Published in PLoS pathogens (01.06.2018)
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Journal Article
Transmission stages dominate trypanosome within-host dynamics during chronic infections
MacGregor, Paula, Savill, Nicholas J, Hall, Deborah, Matthews, Keith R
Published in Cell host & microbe (21.04.2011)
Published in Cell host & microbe (21.04.2011)
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