Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
Gomez-Chou, Sobeyda B, Swidnicka-Siergiejko, Agnieszka Katarzyna, Badi, Niharika, Chavez-Tomar, Myrriah, Lesinski, Gregory B, Bekaii-Saab, Tanios, Farren, Matthew R, Mace, Thomas A, Schmidt, Carl, Liu, Yan, Deng, Defeng, Hwang, Rosa F, Zhou, Liran, Moore, Todd, Chatterjee, Deyali, Wang, Huamin, Leng, Xiaohong, Arlinghaus, Ralph B, Logsdon, Craig D, Cruz-Monserrate, Zobeida
Published in Cancer research (Chicago, Ill.) (15.05.2017)
Published in Cancer research (Chicago, Ill.) (15.05.2017)
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Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma
Noonan, Anne M, Farren, Matthew R, Geyer, Susan M, Huang, Ying, Tahiri, Sanaa, Ahn, Daniel, Mikhail, Sameh, Ciombor, Kristen K, Pant, Shubham, Aparo, Santiago, Sexton, Jennifer, Marshall, John L, Mace, Thomas A, Wu, Christina S, El-Rayes, Bassel, Timmers, Cynthia D, Zwiebel, James, Lesinski, Gregory B, Villalona-Calero, Miguel A, Bekaii-Saab, Tanios S
Published in Molecular therapy (01.06.2016)
Published in Molecular therapy (01.06.2016)
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CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif
Rozanski, Cheryl H, Utley, Adam, Carlson, Louise M, Farren, Matthew R, Murray, Megan, Russell, Lisa M, Nair, Jayakumar R, Yang, ZhengYu, Brady, William, Garrett-Sinha, Lee Ann, Schoenberger, Stephen P, Green, Jonathan M, Boise, Lawrence H, Lee, Kelvin P
Published in The Journal of immunology (1950) (15.05.2015)
Published in The Journal of immunology (1950) (15.05.2015)
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Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients
Talbert, Erin E., Lewis, Heather L., Farren, Matthew R., Ramsey, Mitchell L., Chakedis, Jeffery M., Rajasekera, Priyani, Haverick, Ericka, Sarna, Angela, Bloomston, Mark, Pawlik, Timothy M., Zimmers, Teresa A., Lesinski, Gregory B., Hart, Phil A., Dillhoff, Mary E., Schmidt, Carl R., Guttridge, Denis C.
Published in Journal of cachexia, sarcopenia and muscle (01.04.2018)
Published in Journal of cachexia, sarcopenia and muscle (01.04.2018)
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Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis
Netherby, Colleen, Hensen, Mary L, Miller, Austin, Hu, Qiang, Liu, Song, Bogner, Paul N, Farren, Matthew R, Lee, Kelvin P, Liu, Kebin, Abrams, Scott I
Published in The Journal of clinical investigation (01.10.2013)
Published in The Journal of clinical investigation (01.10.2013)
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Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell- and CXCR3-dependent manner
Ware, Michael Brandon, Phillips, Maggie, McQuinn, Christopher, Zaidi, Mohammad Y, Knochelmann, Hannah M, Greene, Emily, Robinson, Brian, Herting, Cameron J, Mace, Thomas A, Chen, Zhengjia, Zhang, Chao, Farren, Matthew R, Ruggieri, Amanda N, Bowers, Jacob S, Shakya, Reena, Farris, Alton B, Young, Gregory, Carson, 3rd, William E, El-Rayes, Bassel, Paulos, Chrystal M, Lesinski, Gregory B
Published in JCI insight (24.04.2023)
Published in JCI insight (24.04.2023)
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Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis
Waight, Jeremy D, Netherby, Colleen, Hensen, Mary L, Miller, Austin, Hu, Qiang, Liu, Song, Bogner, Paul N, Farren, Matthew R, Lee, Kelvin P, Liu, Kebin, Abrams, Scott I
Published in The Journal of clinical investigation (01.10.2013)
Published in The Journal of clinical investigation (01.10.2013)
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Systemic Immune Activity Predicts Overall Survival in Treatment-Naïve Patients with Metastatic Pancreatic Cancer
Farren, Matthew R, Mace, Thomas A, Geyer, Susan, Mikhail, Sameh, Wu, Christina, Ciombor, Kristen, Tahiri, Sanaa, Ahn, Daniel, Noonan, Anne M, Villalona-Calero, Miguel, Bekaii-Saab, Tanios, Lesinski, Gregory B
Published in Clinical cancer research (15.05.2016)
Published in Clinical cancer research (15.05.2016)
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Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer
Zhang, Yuchen, Ware, Michael B, Zaidi, Mohammad Y, Ruggieri, Amanda N, Olson, Brian M, Komar, Hannah, Farren, Matthew R, Nagaraju, Ganji Purnachandra, Zhang, Chao, Chen, Zhengjia, Sarmiento, Juan M, Ahmed, Rafi, Maithel, Shishir K, El-Rayes, Bassel F, Lesinski, Gregory B
Published in Molecular cancer therapeutics (01.01.2021)
Published in Molecular cancer therapeutics (01.01.2021)
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Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function
Mace, Thomas A., Ware, Michael B., King, Samantha A., Loftus, Shannon, Farren, Matthew R., McMichael, Elizabeth, Scoville, Steven, Geraghty, Connor, Young, Gregory, Carson, William E., Clinton, Steven K., Lesinski, Gregory B.
Published in Scientific reports (25.03.2019)
Published in Scientific reports (25.03.2019)
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A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186
Herting, Cameron J., Farren, Matthew R., Tong, Yan, Liu, Ziyue, O’Neil, Bert, Bekaii-Saab, Tanios, Noonan, Anne, McQuinn, Christopher, Mace, Thomas A., Shaib, Walid, Wu, Christina, El-Rayes, Bassel F., Shahda, Safi, Lesinski, Gregory B.
Published in Cancer Immunology, Immunotherapy (01.11.2021)
Published in Cancer Immunology, Immunotherapy (01.11.2021)
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Inhibiting heat shock protein 90 and the ubiquitin‐proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells
Belalcazar, Astrid, Shaib, Walid L., Farren, Matthew R., Zhang, Chao, Chen, Zhengjia, Yang, Lily, Lesinski, Gregory B., El‐Rayes, Bassel F., Nagaraju, Ganji Purnachandra
Published in Cancer (15.12.2017)
Published in Cancer (15.12.2017)
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The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors
Farren, Matthew R, Hennessey, Rebecca C, Shakya, Reena, Elnaggar, Omar, Young, Gregory, Kendra, Kari, Landesman, Yosef, Elloul, Sivan, Crochiere, Marsha, Klebanov, Boris, Kashyap, Trinayan, Burd, Christin E, Lesinski, Gregory B
Published in Molecular cancer therapeutics (01.03.2017)
Published in Molecular cancer therapeutics (01.03.2017)
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Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
Talbert, Erin E, Yang, Jennifer, Mace, Thomas A, Farren, Matthew R, Farris, Alton B, Young, Gregory S, Elnaggar, Omar, Che, Zheng, Timmers, Cynthia D, Rajasekera, Priyani, Maskarinec, Jennifer M, Bloomston, Mark, Bekaii-Saab, Tanios, Guttridge, Denis C, Lesinski, Gregory B
Published in Molecular cancer therapeutics (01.02.2017)
Published in Molecular cancer therapeutics (01.02.2017)
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Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease
Ware, Michael B., Zaidi, Mohammad Y., Yang, Jennifer, Turgeon, Michael K., Krasinskas, Alyssa, Mace, Thomas A., Keenan, Kaitlin, Farren, Matthew R., Ruggieri, Amanda N., Li, Yiman, Zhang, Chao, Chen, Zhengjia, Young, Gregory S., Elnaggar, Omar, Che, Zheng, Maithel, Shishir K., Bekaii-Saab, Tanios, El-Rayes, Bassel, Lesinski, Gregory B.
Published in British journal of cancer (27.10.2020)
Published in British journal of cancer (27.10.2020)
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Signaling pathways as therapeutic targets in biliary tract cancer
Yang, Jennifer, Farren, Matthew R, Ahn, Daniel, Bekaii-Saab, Tanios, Lesinski, Gregory B
Published in Expert opinion on therapeutic targets (04.05.2017)
Published in Expert opinion on therapeutic targets (04.05.2017)
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Immunologic alterations in the pancreatic cancer microenvironment of patients treated with neoadjuvant chemotherapy and radiotherapy
Farren, Matthew R, Sayegh, Layal, Ware, Michael Brandon, Chen, Hsiao-Rong, Gong, Jingjing, Liang, Yan, Krasinskas, Alyssa, Maithel, Shishir K, Zaidi, Mohammad, Sarmiento, Juan M, Kooby, David, Patel, Pretesh, El-Rayes, Bassel, Shaib, Walid, Lesinski, Gregory B
Published in JCI insight (16.01.2020)
Published in JCI insight (16.01.2020)
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Circulating interleukin-6 is associated with disease progression, but not cachexia in pancreatic cancer
Ramsey, Mitchell L., Talbert, Erin, Ahn, Daniel, Bekaii-Saab, Tanios, Badi, Niharika, Bloomston, P. Mark, Conwell, Darwin L., Cruz-Monserrate, Zobeida, Dillhoff, Mary, Farren, Matthew R., Hinton, Alice, Krishna, Somashekar G., Lesinski, Gregory B., Mace, Thomas, Manilchuk, Andrei, Noonan, Anne, Pawlik, Timothy M., Rajasekera, Priyani V., Schmidt, Carl, Guttridge, Denis, Hart, Phil A.
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.01.2019)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.01.2019)
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Tumor-induced STAT3 signaling in myeloid cells impairs dendritic cell generation by decreasing PKCβII abundance
Farren, Matthew R, Carlson, Louise M, Netherby, Colleen S, Lindner, Inna, Li, Pui-Kai, Gabrilovich, Dmitry I, Abrams, Scott I, Lee, Kelvin P
Published in Science signaling (18.02.2014)
Published in Science signaling (18.02.2014)
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Stressful presentations: mild cold stress in laboratory mice influences phenotype of dendritic cells in naïve and tumor-bearing mice
Kokolus, Kathleen M, Spangler, Haley M, Povinelli, Benjamin J, Farren, Matthew R, Lee, Kelvin P, Repasky, Elizabeth A
Published in Frontiers in immunology (2014)
Published in Frontiers in immunology (2014)
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