EPHA2 Is a Predictive Biomarker of Resistance and a Potential Therapeutic Target for Improving Antiepidermal Growth Factor Receptor Therapy in Colorectal Cancer
Martini, Giulia, Cardone, Claudia, Vitiello, Pietro Paolo, Belli, Valentina, Napolitano, Stefania, Troiani, Teresa, Ciardiello, Davide, Della Corte, Carminia Maria, Morgillo, Floriana, Matrone, Nunzia, Sforza, Vincenzo, Papaccio, Gianpaolo, Desiderio, Vincenzo, Paul, Mariel C, Moreno-Viedma, Veronica, Normanno, Nicola, Rachiglio, Anna Maria, Tirino, Virginia, Maiello, Evaristo, Latiano, Tiziana Pia, Rizzi, Daniele, Signoriello, Giuseppe, Sibilia, Maria, Ciardiello, Fortunato, Martinelli, Erika
Published in Molecular cancer therapeutics (01.04.2019)
Published in Molecular cancer therapeutics (01.04.2019)
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Journal Article
Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines
Vitiello, Pietro Paolo, Cardone, Claudia, Martini, Giulia, Ciardiello, Davide, Belli, Valentina, Matrone, Nunzia, Barra, Giusi, Napolitano, Stefania, Della Corte, Carmina, Turano, Mimmo, Furia, Maria, Troiani, Teresa, Morgillo, Floriana, De Vita, Ferdinando, Ciardiello, Fortunato, Martinelli, Erika
Published in Journal of experimental & clinical cancer research (28.01.2019)
Published in Journal of experimental & clinical cancer research (28.01.2019)
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Journal Article
Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
Vitiello, Pietro Paolo, Martini, Giulia, Mele, Luigi, Giunta, Emilio Francesco, De Falco, Vincenzo, Ciardiello, Davide, Belli, Valentina, Cardone, Claudia, Matrone, Nunzia, Poliero, Luca, Tirino, Virginia, Napolitano, Stefania, Della Corte, Carminia, Selvaggi, Francesco, Papaccio, Gianpaolo, Troiani, Teresa, Morgillo, Floriana, Desiderio, Vincenzo, Ciardiello, Fortunato, Martinelli, Erika
Published in Journal of experimental & clinical cancer research (06.01.2021)
Published in Journal of experimental & clinical cancer research (06.01.2021)
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Journal Article
Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models
Belli, Valentina, Matrone, Nunzia, Napolitano, Stefania, Migliardi, Giorgia, Cottino, Francesca, Bertotti, Andrea, Trusolino, Livio, Martinelli, Erika, Morgillo, Floriana, Ciardiello, Davide, De Falco, Vincenzo, Giunta, Emilio Francesco, Bracale, Umberto, Ciardiello, Fortunato, Troiani, Teresa
Published in Journal of experimental & clinical cancer research (04.06.2019)
Published in Journal of experimental & clinical cancer research (04.06.2019)
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Journal Article
Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype
Ciardiello, Davide, Blauensteiner, Bernadette, Matrone, Nunzia, Belli, Valentina, Mohr, Thomas, Vitiello, Pietro Paolo, Martini, Giulia, Poliero, Luca, Cardone, Claudia, Napolitano, Stefania, De Falco, Vincenzo, Giunta, Emilio Francesco, Ciaramella, Vincenza, Corte, Carminia della, Barra, Giusi, Selvaggi, Francesco, Franco, Renato, Marino, Federica Zito, Cuomo, Antonio, Morgillo, Floriana, Troiani, Teresa, Sibilia, Maria, Ciardiello, Fortunato, Martinelli, Erika
Published in Medical oncology (Northwood, London, England) (01.03.2021)
Published in Medical oncology (Northwood, London, England) (01.03.2021)
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Journal Article
A functional connection between dyskerin and energy metabolism
Angrisani, Alberto, Matrone, Nunzia, Belli, Valentina, Vicidomini, Rosario, Di Maio, Nunzia, Turano, Mimmo, Scialò, Filippo, Netti, Paolo Antonio, Porcellini, Antonio, Furia, Maria
Published in Redox biology (01.04.2018)
Published in Redox biology (01.04.2018)
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A dynamic link between H/ACA snoRNP components and cytoplasmic stress granules
Belli, Valentina, Matrone, Nunzia, Sagliocchi, Serena, Incarnato, Rosa, Conte, Andrea, Pizzo, Elio, Turano, Mimmo, Angrisani, Alberto, Furia, Maria
Published in Biochimica et biophysica acta. Molecular cell research (01.12.2019)
Published in Biochimica et biophysica acta. Molecular cell research (01.12.2019)
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Journal Article
AXL is a predictor of poor survival and of resistance to anti-EGFR therapy in RAS wild-type metastatic colorectal cancer
Cardone, Claudia, Blauensteiner, Bernadette, Moreno-Viedma, Veronica, Martini, Giulia, Simeon, Vittorio, Vitiello, Pietro P., Ciardiello, Davide, Belli, Valentina, Matrone, Nunzia, Troiani, Teresa, Morgillo, Floriana, Zito Marino, Federica, Dentice, Monica, Nappi, Annarita, Boccaccino, Alessandra, Antoniotti, Carlotta, Cremolini, Chiara, Pietrantonio, Filippo, Prager, Gerald W., Normanno, Nicola, Maiello, Evaristo, Argiles, Guillem, Elez, Elena, Signoriello, Giuseppe, Franco, Renato, Falcone, Alfredo, Tabernero, Josep, Sibilia, Maria, Ciardiello, Fortunato, Martinelli, Erika
Published in European journal of cancer (1990) (01.10.2020)
Published in European journal of cancer (1990) (01.10.2020)
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Journal Article
Abstract 2841: Her2/neu expression as potential marker of regorafenib resistance in CRC
Vecchione, Loredana, Napolitano, Stefania, Belli, Valentina, Martinelli, Erika, Matrone, Nunzia, Hapke, Christophe, Keilholz, Ulrich, Tabernero, Josep, Ciardiello, Fortunato, Troiani, Teresa
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 4904: PD-L1 pathway activation as an escape mechanism of resistance to MEK inhibitor treatment in human colorectal cancer models
Napolitano, Stefania, Matrone, Nunzia, Belli, Valentina, Falco, Vincenzo De, Martinelli, Erika, Kopetz, Scott, Ciardiello, Fortunato, Troiani, Teresa
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer
Belli, Valentina, Sforza, Vincenzo, Cardone, Claudia, Martinelli, Erika, Barra, Giusi, Matrone, Nunzia, Napolitano, Stefania, Morgillo, Floriana, Tuccillo, Concetta, Federico, Alessandro, Dallio, Marcello, Loguercio, Carmelina, Gravina, Antonietta Gerarda, De Palma, Raffaele, Ciardiello, Fortunato, Troiani, Teresa
Published in Oncotarget (15.09.2017)
Published in Oncotarget (15.09.2017)
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Journal Article
Abstract 2627: Inhibition of TGFβ in colorectal cancer cells is associated with a compensatory activation of AXL and p38 MAPK signaling pathways
Ciardiello, Davide, Vitiello, Pietro Paolo, Matrone, Nunzia, Belli, Valentina, Cardone, Claudia, Poliero, Luca, Borrelli, Carola, Arrichiello, Gianluca, Martini, Giulia, Ciaramella, Vincenza, Barra, Giusi, Morgillo, Floriana, Troiani, Teresa, Melisi, Davide, Ciardiello, Fortunato, Martinelli, Erika
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 295: Synergism between oxaliplatin or irinotecan with the PARP inhibitor niraparib in a preclinical model of KRAS/BRAF mutated colorectal cancer is associated with MSI status
Vitiello, Pietro Paolo, Ciardiello, Davide, Cardone, Claudia, Martini, Giulia, Belli, Valentina, Matrone, Nunzia, Poliero, Luca, Borrelli, Carola, Vitale, Pasquale, Zanaletti, Nicoletta, Troiani, Teresa, Melisi, Davide, Ciardiello, Fortunato, Martinelli, Erika
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Macrophage Migration Inhibitory Factor Is a Molecular Determinant of the Anti-EGFR Monoclonal Antibody Cetuximab Resistance in Human Colorectal Cancer Cells
Russo, Rosita, Matrone, Nunzia, Belli, Valentina, Ciardiello, Davide, Valletta, Mariangela, Esposito, Sabrina, Pedone, Paolo Vincenzo, Ciardiello, Fortunato, Troiani, Teresa, Chambery, Angela
Published in Cancers (25.09.2019)
Published in Cancers (25.09.2019)
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Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells
Napolitano, Stefania, Martini, Giulia, Martinelli, Erika, Della Corte, Carminia Maria, Morgillo, Floriana, Belli, Valentina, Cardone, Claudia, Matrone, Nunzia, Ciardiello, Fortunato, Troiani, Teresa
Published in Oncotarget (10.10.2017)
Published in Oncotarget (10.10.2017)
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