Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
Helgason, Hannes, Eiriksdottir, Thjodbjorg, Ulfarsson, Magnus O, Choudhary, Abhishek, Lund, Sigrun H, Ivarsdottir, Erna V, Hjorleifsson Eldjarn, Grimur, Einarsson, Gudmundur, Ferkingstad, Egil, Moore, Kristjan H. S, Honarpour, Narimon, Liu, Thomas, Wang, Huei, Hucko, Thomas, Sabatine, Marc S, Morrow, David A, Giugliano, Robert P, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Bundgaard, Henning, Erikstrup, Christian, Arnar, David O, Thorgeirsson, Gudmundur, Masson, Gísli, Magnusson, Olafur Th, Saemundsdottir, Jona, Gretarsdottir, Solveig, Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Helgadottir, Anna, Sulem, Patrick, Thorsteinsdottir, Unnur, Holm, Hilma, Gudbjartsson, Daniel, Stefansson, Kari
Published in JAMA : the journal of the American Medical Association (22.08.2023)
Published in JAMA : the journal of the American Medical Association (22.08.2023)
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Journal Article
The nature of nurture: Effects of parental genotypes
Kong, Augustine, Thorleifsson, Gudmar, Frigge, Michael L, Vilhjalmsson, Bjarni J, Young, Alexander I, Thorgeirsson, Thorgeir E, Benonisdottir, Stefania, Oddsson, Asmundur, Halldorsson, Bjarni V, Masson, Gisli, Gudbjartsson, Daniel F, Helgason, Agnar, Bjornsdottir, Gyda, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Science (American Association for the Advancement of Science) (26.01.2018)
Published in Science (American Association for the Advancement of Science) (26.01.2018)
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Journal Article
Weighting sequence variants based on their annotation increases power of whole-genome association studies
Sveinbjornsson, Gardar, Albrechtsen, Anders, Zink, Florian, Gudjonsson, Sigurjón A, Oddson, Asmundur, Másson, Gísli, Holm, Hilma, Kong, Augustine, Thorsteinsdottir, Unnur, Sulem, Patrick, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Nature genetics (01.03.2016)
Published in Nature genetics (01.03.2016)
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Journal Article
Characterizing mutagenic effects of recombination through a sequence-level genetic map
Halldorsson, Bjarni V, Palsson, Gunnar, Stefansson, Olafur A, Jonsson, Hakon, Hardarson, Marteinn T, Eggertsson, Hannes P, Gunnarsson, Bjarni, Oddsson, Asmundur, Halldorsson, Gisli H, Zink, Florian, Gudjonsson, Sigurjon A, Frigge, Michael L, Thorleifsson, Gudmar, Sigurdsson, Asgeir, Stacey, Simon N, Sulem, Patrick, Masson, Gisli, Helgason, Agnar, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Science (American Association for the Advancement of Science) (25.01.2019)
Published in Science (American Association for the Advancement of Science) (25.01.2019)
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Journal Article
Rate of de novo mutations and the importance of father’s age to disease risk
Kong, Augustine, Frigge, Michael L., Masson, Gisli, Besenbacher, Soren, Sulem, Patrick, Magnusson, Gisli, Gudjonsson, Sigurjon A., Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Wong, Wendy S. W., Sigurdsson, Gunnar, Walters, G. Bragi, Steinberg, Stacy, Helgason, Hannes, Thorleifsson, Gudmar, Gudbjartsson, Daniel F., Helgason, Agnar, Magnusson, Olafur Th, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (London) (23.08.2012)
Published in Nature (London) (23.08.2012)
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Journal Article
A direct characterization of human mutation based on microsatellites
Sun, James X, Helgason, Agnar, Masson, Gisli, Ebenesersdóttir, Sigríður Sunna, Li, Heng, Mallick, Swapan, Gnerre, Sante, Patterson, Nick, Kong, Augustine, Reich, David, Stefansson, Kari
Published in Nature genetics (01.10.2012)
Published in Nature genetics (01.10.2012)
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Journal Article
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Flannick, Jason, Thorleifsson, Gudmar, Beer, Nicola L, Jacobs, Suzanne B R, Grarup, Niels, Burtt, Noël P, Mahajan, Anubha, Fuchsberger, Christian, Atzmon, Gil, Benediktsson, Rafn, Blangero, John, Bowden, Don W, Brandslund, Ivan, Brosnan, Julia, Burslem, Frank, Chambers, John, Cho, Yoon Shin, Christensen, Cramer, Douglas, Desirée A, Duggirala, Ravindranath, Dymek, Zachary, Farjoun, Yossi, Fennell, Timothy, Fontanillas, Pierre, Forsén, Tom, Gabriel, Stacey, Glaser, Benjamin, Gudbjartsson, Daniel F, Hanis, Craig, Hansen, Torben, Hreidarsson, Astradur B, Hveem, Kristian, Ingelsson, Erik, Isomaa, Bo, Johansson, Stefan, Jørgensen, Torben, Jørgensen, Marit Eika, Kathiresan, Sekar, Kong, Augustine, Kooner, Jaspal, Kravic, Jasmina, Laakso, Markku, Lee, Jong-Young, Lind, Lars, Lindgren, Cecilia M, Linneberg, Allan, Masson, Gisli, Meitinger, Thomas, Mohlke, Karen L, Molven, Anders, Morris, Andrew P, Potluri, Shobha, Rauramaa, Rainer, Ribel-Madsen, Rasmus, Richard, Ann-Marie, Rolph, Tim, Salomaa, Veikko, Segrè, Ayellet V, Skärstrand, Hanna, Steinthorsdottir, Valgerdur, Stringham, Heather M, Sulem, Patrick, Tai, E Shyong, Teo, Yik Ying, Teslovich, Tanya, Thorsteinsdottir, Unnur, Trimmer, Jeff K, Tuomi, Tiinamaija, Tuomilehto, Jaakko, Vaziri-Sani, Fariba, Voight, Benjamin F, Wilson, James G, Boehnke, Michael, McCarthy, Mark I, Njølstad, Pål R, Pedersen, Oluf, Groop, Leif, Cox, David R, Stefansson, Kari, Altshuler, David
Published in Nature genetics (01.04.2014)
Published in Nature genetics (01.04.2014)
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Journal Article
Multi-nucleotide de novo Mutations in Humans
Besenbacher, Søren, Sulem, Patrick, Helgason, Agnar, Helgason, Hannes, Kristjansson, Helgi, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Magnusson, Olafur Th, Thorsteinsdottir, Unnur, Masson, Gisli, Kong, Augustine, Gudbjartsson, Daniel F, Stefansson, Kari
Published in PLoS genetics (15.11.2016)
Published in PLoS genetics (15.11.2016)
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Journal Article
Identification of a large set of rare complete human knockouts
Sulem, Patrick, Helgason, Hannes, Oddson, Asmundur, Stefansson, Hreinn, Gudjonsson, Sigurjon A, Zink, Florian, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur Th, Kong, Augustine, Helgason, Agnar, Holm, Hilma, Thorsteinsdottir, Unnur, Masson, Gisli, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Nature genetics (01.05.2015)
Published in Nature genetics (01.05.2015)
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Journal Article
A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis
Kristjansson, Ragnar P., Benonisdottir, Stefania, Davidsson, Olafur B., Oddsson, Asmundur, Tragante, Vinicius, Sigurdsson, Jon K., Stefansdottir, Lilja, Jonsson, Stefan, Jensson, Brynjar O., Arthur, Joseph G., Arnadottir, Gudny A., Sulem, Gerald, Halldorsson, Bjarni V., Gunnarsson, Bjarni, Halldorsson, Gisli H., Stefansson, Olafur A., Oskarsson, Gudjon R., Deaton, Aimee M., Olafsson, Isleifur, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Onundarson, Pall T., Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn R., Ludviksdottir, Dora, Olafsdottir, Thorunn A., Rafnar, Thorunn, Masson, Gisli, Zink, Florian, Bjornsdottir, Gyda, Magnusson, Olafur Th, Bjornsdottir, Unnur S., Thorleifsson, Gudmar, Norddahl, Gudmundur L., Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Sulem, Patrick, Stefansson, Kari
Published in Nature genetics (01.02.2019)
Published in Nature genetics (01.02.2019)
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Journal Article
Fine-scale recombination rate differences between sexes, populations and individuals
Gudbjartsson, Daniel F, Gudjonsson, Sigurjon A, Kristinsson, Kari Th, Helgason, Agnar, Gylfason, Arnaldur, Sigurdsson, Asgeir, Masson, Gisli, Stefansson, Kari, Frigge, Michael L, Walters, G. Bragi, Thorsteinsdottir, Unnur, Thorleifsson, Gudmar, Kong, Augustine, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg
Published in Nature (London) (28.10.2010)
Published in Nature (London) (28.10.2010)
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Journal Article
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma
Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R, Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S, Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A, Koppelman, Gerard H, Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Johnston, James A, Jonsdottir, Ingileif, Stefansson, Kari
Published in PLoS genetics (08.03.2017)
Published in PLoS genetics (08.03.2017)
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Journal Article
Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2
Haraldsdottir, Sigurdis, Rafnar, Thorunn, Frankel, Wendy L., Einarsdottir, Sylvia, Sigurdsson, Asgeir, Hampel, Heather, Snaebjornsson, Petur, Masson, Gisli, Weng, Daniel, Arngrimsson, Reynir, Kehr, Birte, Yilmaz, Ahmet, Haraldsson, Stefan, Sulem, Patrick, Stefansson, Tryggvi, Shields, Peter G., Sigurdsson, Fridbjorn, Bekaii-Saab, Tanios, Moller, Pall H., Steinarsdottir, Margret, Alexiusdottir, Kristin, Hitchins, Megan, Pritchard, Colin C., de la Chapelle, Albert, Jonasson, Jon G., Goldberg, Richard M., Stefansson, Kari
Published in Nature communications (03.05.2017)
Published in Nature communications (03.05.2017)
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Journal Article
Loss-of-function variants in ATM confer risk of gastric cancer
Helgason, Hannes, Rafnar, Thorunn, Olafsdottir, Halla S, Jonasson, Jon G, Sigurdsson, Asgeir, Stacey, Simon N, Jonasdottir, Adalbjorg, Tryggvadottir, Laufey, Alexiusdottir, Kristin, Haraldsson, Asgeir, le Roux, Louise, Gudmundsson, Julius, Johannsdottir, Hrefna, Oddsson, Asmundur, Gylfason, Arnaldur, Magnusson, Olafur T, Masson, Gisli, Jonsson, Thorvaldur, Skuladottir, Halla, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Nature genetics (01.08.2015)
Published in Nature genetics (01.08.2015)
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Journal Article
Mutations in BRIP1 confer high risk of ovarian cancer
Rafnar, Thorunn, Stefansson, Kari, Gudbjartsson, Daniel F, Sulem, Patrick, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Besenbacher, Soren, Lundin, Pär, Stacey, Simon N, Gudmundsson, Julius, Magnusson, Olafur T, le Roux, Louise, Orlygsdottir, Gudbjorg, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Gylfason, Arnaldur, Tryggvadottir, Laufey, Jonasson, Jon G, de Juan, Ana, Ortega, Eugenia, Ramon-Cajal, Jose M, García-Prats, Maria D, Mayordomo, Carlos, Panadero, Angeles, Rivera, Fernando, Aben, Katja K H, van Altena, Anne M, Massuger, Leon F A G, Aavikko, Mervi, Kujala, Paula M, Staff, Synnöve, Aaltonen, Lauri A, Olafsdottir, Kristrun, Bjornsson, Johannes, Kong, Augustine, Salvarsdottir, Anna, Saemundsson, Hafsteinn, Olafsson, Karl, Benediktsdottir, Kristrun R, Gulcher, Jeffrey, Masson, Gisli, Kiemeney, Lambertus A, Mayordomo, Jose I, Thorsteinsdottir, Unnur
Published in Nature genetics (01.11.2011)
Published in Nature genetics (01.11.2011)
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Journal Article
The rate of meiotic gene conversion varies by sex and age
Halldorsson, Bjarni V, Hardarson, Marteinn T, Kehr, Birte, Styrkarsdottir, Unnur, Gylfason, Arnaldur, Thorleifsson, Gudmar, Zink, Florian, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sulem, Patrick, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Kong, Augustine, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Nature genetics (01.11.2016)
Published in Nature genetics (01.11.2016)
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Journal Article
Population-level deficit of homozygosity unveils CPSF3 as an intellectual disability syndrome gene
Arnadottir, Gudny A., Oddsson, Asmundur, Jensson, Brynjar O., Gisladottir, Svanborg, Simon, Mariella T., Arnthorsson, Asgeir O., Katrinardottir, Hildigunnur, Fridriksdottir, Run, Ivarsdottir, Erna V., Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Barrick, Rebekah, Saemundsdottir, Jona, le Roux, Louise, Oskarsson, Gudjon R., Asmundsson, Jurate, Steffensen, Thora, Gudmundsson, Kjartan R., Ludvigsson, Petur, Jonsson, Jon J., Masson, Gisli, Jonsdottir, Ingileif, Holm, Hilma, Jonasson, Jon G., Magnusson, Olafur Th, Thorarensen, Olafur, Abdenur, Jose, Norddahl, Gudmundur L., Gudbjartsson, Daniel F., Bjornsson, Hans T., Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Nature communications (04.02.2022)
Published in Nature communications (04.02.2022)
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Journal Article
Physical and neurobehavioral determinants of reproductive onset and success
Day, Felix R, Helgason, Hannes, Chasman, Daniel I, Rose, Lynda M, Loh, Po-Ru, Scott, Robert A, Helgason, Agnar, Kong, Augustine, Masson, Gisli, Magnusson, Olafur Th, Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Buring, Julie E, Ridker, Paul M, Sulem, Patrick, Stefansson, Kari, Ong, Ken K, Perry, John R B
Published in Nature genetics (01.06.2016)
Published in Nature genetics (01.06.2016)
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Journal Article
Detection of sharing by descent, long-range phasing and haplotype imputation
Kong, Augustine, Stefansson, Kari, Masson, Gisli, Frigge, Michael L, Gylfason, Arnaldur, Zusmanovich, Pasha, Thorleifsson, Gudmar, Olason, Pall I, Ingason, Andres, Steinberg, Stacy, Rafnar, Thorunn, Sulem, Patrick, Mouy, Magali, Jonsson, Frosti, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Stefansson, Hreinn
Published in Nature genetics (01.09.2008)
Published in Nature genetics (01.09.2008)
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Journal Article
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis
Sigurdsson, Snaevar, Alexandersson, Kristjan F., Sulem, Patrick, Feenstra, Bjarke, Gudmundsdottir, Steinunn, Halldorsson, Gisli H., Olafsson, Sigurgeir, Sigurdsson, Asgeir, Rafnar, Thorunn, Thorgeirsson, Thorgeir, Sørensen, Erik, Nordholm-Carstensen, Andreas, Burcharth, Jakob, Andersen, Jens, Jørgensen, Henrik Stig, Possfelt-Møller, Emma, Ullum, Henrik, Thorleifsson, Gudmar, Masson, Gisli, Thorsteinsdottir, Unnur, Melbye, Mads, Gudbjartsson, Daniel F., Stefansson, Tryggvi, Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature communications (06.06.2017)
Published in Nature communications (06.06.2017)
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