Multistep Reaction Based De Novo Drug Design: Generating Synthetically Feasible Design Ideas
Masek, Brian B, Baker, David S, Dorfman, Roman J, DuBrucq, Karen, Francis, Victoria C, Nagy, Stephan, Richey, Bree L, Soltanshahi, Farhad
Published in Journal of chemical information and modeling (25.04.2016)
Published in Journal of chemical information and modeling (25.04.2016)
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Journal Article
Virtual Screening for R-Groups, including Predicted pIC50 Contributions, within Large Structural Databases, Using Topomer CoMFA
Cramer, Richard D, Cruz, Phillip, Stahl, Gunther, Curtiss, William C, Campbell, Brian, Masek, Brian B, Soltanshahi, Farhad
Published in Journal of Chemical Information and Modeling (24.11.2008)
Published in Journal of Chemical Information and Modeling (24.11.2008)
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Journal Article
Naphtho[2,1-b][1,5] and [1,2-f][1,4]oxazocines as selective NK1 antagonists
OHNMACHT, Cyrus J, ALBERT, Jeffrey S, BERNSTEIN, Peter R, RUMSEY, William L, MASEK, Brian B, DEMBOFSKY, Bruce T, KOETHER, Gerard M, ANDISIK, Donald W, AHARONY, David
Published in Bioorganic & medicinal chemistry (15.05.2004)
Published in Bioorganic & medicinal chemistry (15.05.2004)
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Journal Article
Sharing Chemical Information without Sharing Chemical Structure
Masek, Brian B, Shen, Lingling, Smith, Karl M, Pearlman, Robert S
Published in Journal of chemical information and modeling (01.02.2008)
Published in Journal of chemical information and modeling (01.02.2008)
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Journal Article
New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)quinoline derivatives
Bradbury, Robert H, Allott, Christopher P, Dennis, Michael, Fisher, Eric, Major, John S, Masek, Brian B, Oldham, Alec A, Pearce, Robert J, Rankine, Neil
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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Journal Article
Design and optimization of cyclized NK1 antagonists with controlled atropisomeric properties
Albert, JS, Ohnmacht, C, Bernstein, PR, Rumsey, WL, Aharony, D, Masek, BB, Dembofsky, BT, Koether, GM, Potts, W, Evenden, JL
Published in Tetrahedron (10.05.2004)
Published in Tetrahedron (10.05.2004)
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Journal Article
Molecular shape comparison of angiotensin II receptor antagonists
Masek, Brian B, Merchant, Arshad, Matthew, James B
Published in Journal of medicinal chemistry (30.04.1993)
Published in Journal of medicinal chemistry (30.04.1993)
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Journal Article
Determining the conformations of organic macrocycles through a combination of Dale's rules, molecular mechanics, solid-state carbon-13 NMR and x-ray diffraction
Masek, Brian B, Santarsiero, Bernard D, Dougherty, Dennis A
Published in Journal of the American Chemical Society (01.07.1987)
Published in Journal of the American Chemical Society (01.07.1987)
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Journal Article
New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties and structure-activity relationships of 2-alkylbenzimidazole derivatives
Thomas, Andrew P, Allott, Christopher P, Gibson, Keith H, Major, John S, Masek, Brian B, Oldham, Alec A, Ratcliffe, Arnold H, Roberts, David A, Russell, Simon T, Thomason, Douglas A
Published in Journal of medicinal chemistry (01.03.1992)
Published in Journal of medicinal chemistry (01.03.1992)
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Journal Article
N-Aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP Potassium Channel Openers. Modifications on the Western Region
Ohnmacht, Cyrus J, Russell, Keith, Empfield, James R, Frank, Cathy A, Gibson, Keith H, Mayhugh, Daniel R, McLaren, Frances M, Shapiro, Howard S, Brown, Frederick J, Trainor, Diane A, Ceccarelli, Christopher, Lin, Margaret M, Masek, Brian B, Forst, Janet M, Harris, Robert J, Hulsizer, James M, Lewis, Joseph J, Silverman, Stuart M, Smith, Reed W, Warwick, Paul J, Kau, Sen T, Chun, Alexa L, Grant, Thomas L, Howe, Burton B, Li, Jack H, Trivedi, Shephali, Halterman, Tracy J, Yochim, Christopher, Dyroff, Martin C, Neilson, Kathleen L
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
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Journal Article
Design and optimization of cyclized NK 1 antagonists with controlled atropisomeric properties
Albert, Jeffrey S, Ohnmacht, Cyrus, Bernstein, Peter R, Rumsey, William L, Aharony, David, Masek, Brian B, Dembofsky, Bruce T, Koether, Gerard M, Potts, William, Evenden, John L
Published in Tetrahedron (2004)
Published in Tetrahedron (2004)
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Journal Article
Naphtho[2,1- b][1,5] and [1,2- f][1,4]oxazocines as selective NK 1 antagonists
Ohnmacht, Cyrus J., Albert, Jeffrey S., Bernstein, Peter R., Rumsey, William L., Masek, Brian B., Dembofsky, Bruce T., Koether, Gerard M., Andisik, Donald W., Aharony, David
Published in Bioorganic & medicinal chemistry (2004)
Published in Bioorganic & medicinal chemistry (2004)
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Journal Article
New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties, and structure-activity relationships of 2-alkyl benzimidazole derivatives
Thomas, A P, Allott, C P, Gibson, K H, Major, J S, Masek, B B, Oldham, A A, Ratcliffe, A H, Roberts, D A, Russell, S T, Thomason, D A
Published in Journal of medicinal chemistry (06.03.1992)
Published in Journal of medicinal chemistry (06.03.1992)
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Journal Article
N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: K-ATP potassium channel openers. Modifications on the western region
Ohnmacht, CJ, Russell, K, Empfield, Frank, CA, Gibson, KH, Mayhugh, DR, McLaren, FM, Shapiro, HS, Brown, FJ, Trainor, DA, Ceccarelli, C, Lin, MM, Masek, BB, Forst, JM, Harris, RJ, Hulsizer, JM, Lewis, JJ, Silverman, SM, Smith, RW, Warwick, PJ, Kau, ST, Chun, AL, Grant, TL, Howe, BB, Li, JH, Trivedi, S, Halterman, TJ, Yochim, C, Dyroff, MC, Kirkland, M, Neilson, KL
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
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Journal Article
ChemInform Abstract: Sharing Chemical Information Without Sharing Chemical Structure
Masek, Brian B., Shen, Lingling, Smith, Karl M., Pearlman, Robert S.
Published in ChemInform (20.05.2008)
Published in ChemInform (20.05.2008)
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Journal Article
ChemInform Abstract: Virtual Screening for R-Groups, Including Predicted pIC50 Contributions, within Large Structural Databases, Using Topomer CoMFA
Cramer, Richard D., Cruz, Phillip, Stahl, Gunther, Curtiss, William C., Campbell, Brian, Masek, Brian B., Soltanshahi, Farhad
Published in ChemInform (14.04.2009)
Published in ChemInform (14.04.2009)
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Journal Article
N -Aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: K ATP Potassium Channel Openers. Modifications on the Western Region
Ohnmacht, Cyrus J., Russell, Keith, Empfield, James R., Frank, Cathy A., Gibson, Keith H., Mayhugh, Daniel R., McLaren, Frances M., Shapiro, Howard S., Brown, Frederick J., Trainor, Diane A., Ceccarelli, Christopher, Lin, Margaret M., Masek, Brian B., Forst, Janet M., Harris, Robert J., Hulsizer, James M., Lewis, Joseph J., Silverman, Stuart M., Smith, Reed W., Warwick, Paul J., Kau, Sen T., Chun, Alexa L., Grant, Thomas L., Howe, Burton B., Li, Jack H., Trivedi, Shephali, Halterman, Tracy J., Yochim, Christopher, Dyroff, Martin C., M.Kirkland, and, Neilson, Kathleen L.
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
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Journal Article