Surotomycin Demonstrates Low In Vitro Frequency of Resistance and Rapid Bactericidal Activity in Clostridium difficile, Enterococcus faecalis, and Enterococcus faecium
MASCIO, Carmela T. M, CHESNEL, Laurent, THORNE, Grace, SILVERMAN, Jared A
Published in Antimicrobial agents and chemotherapy (01.07.2014)
Published in Antimicrobial agents and chemotherapy (01.07.2014)
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In Vitro and In Vivo Characterization of CB-183,315, a Novel Lipopeptide Antibiotic for Treatment of Clostridium difficile
MASCIO, Carmela T. M, MORTIN, Lawrence I, HOWLAND, Karen T, VAN PRAAGH, Andrew D. G, SHUXIN ZHANG, ARYA, Anu, CHUONG, Cun Lan, CHUNFENG KANG, TONGCHUAN LI, SILVERMAN, Jared A
Published in Antimicrobial Agents and Chemotherapy (01.10.2012)
Published in Antimicrobial Agents and Chemotherapy (01.10.2012)
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Structure–Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea
Yin, Ning, Li, Jing, He, Yong, Herradura, Prudencio, Pearson, Andre, Mesleh, Michael F, Mascio, Carmela T, Howland, Karen, Steenbergen, Judith, Thorne, Grace M, Citron, Diane, Van Praagh, Andrew D. G, Mortin, Lawrence I, Keith, Dennis, Silverman, Jared, Metcalf, Chester
Published in Journal of medicinal chemistry (25.06.2015)
Published in Journal of medicinal chemistry (25.06.2015)
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Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties
NGUYEN, Kien T, XIAOWEI HE, BRIAN, Paul, BALTZ, Richard H, ALEXANDER, Dylan C, CHEN LI, GU, Jian-Qiao, MASCIO, Carmela, VAN PRAAGH, Andrew, MORTIN, Larry, MIN CHU, SILVERMAN, Jared A
Published in Antimicrobial Agents and Chemotherapy (01.04.2010)
Published in Antimicrobial Agents and Chemotherapy (01.04.2010)
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Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions
Alexander, Dylan C, Rock, Jessica, Gu, Jian-Qiao, Mascio, Carmela, Chu, Min, Brian, Paul, Baltz, Richard H
Published in Journal of antibiotics (01.01.2011)
Published in Journal of antibiotics (01.01.2011)
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Discovery and development of surotomycin for the treatment of Clostridium difficile
Knight-Connoni, Victoria, Mascio, Carmela, Chesnel, Laurent, Silverman, Jared
Published in Journal of Industrial Microbiology & Biotechnology (01.03.2016)
Published in Journal of Industrial Microbiology & Biotechnology (01.03.2016)
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Book Review
Effects of surotomycin on Clostridium difficile viability and toxin production in vitro
Bouillaut, Laurent, McBride, Shonna, Sorg, Joseph A, Schmidt, Diane J, Suarez, José M, Tzipori, Saul, Mascio, Carmela, Chesnel, Laurent, Sonenshein, A L
Published in Antimicrobial agents and chemotherapy (01.07.2015)
Published in Antimicrobial agents and chemotherapy (01.07.2015)
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Reduced pulmonary surfactant interaction of daptomycin analogs via tryptophan replacement with alternative amino acids
He, Yong, Li, Jing, Yin, Nin, Herradura, Prudencio S., Martel, Larry, Zhang, Yanzhi, Pearson, Andre L., Kulkarni, Vidya, Mascio, Carmela, Howland, Karen, Silverman, Jared A., Keith, Dennis D., Metcalf, Chester A.
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
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