Successful skipping of abnormal pseudoexon by antisense oligonucleotides in vitro for a patient with beta-propeller protein-associated neurodegeneration
Yamada, Mamiko, Maeta, Kazuhiro, Suzuki, Hisato, Kurosawa, Ryo, Takenouchi, Toshiki, Awaya, Tomonari, Ajiro, Masahiko, Takeuchi, Atsuko, Nishio, Hisahide, Hagiwara, Masatoshi, Miya, Fuyuki, Matsuo, Masafumi, Kosaki, Kenjiro
Published in Scientific reports (18.03.2024)
Published in Scientific reports (18.03.2024)
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Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model
Ichisima, Jose, Suzuki, Naoya M, Samata, Bumpei, Awaya, Tomonari, Takahashi, Jun, Hagiwara, Masatoshi, Nakahata, Tatsutoshi, Saito, Megumu K
Published in Journal of human genetics (01.05.2019)
Published in Journal of human genetics (01.05.2019)
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Journal Article
Synergistic cooperation of PDI family members in peroxiredoxin 4-driven oxidative protein folding
Sato, Yoshimi, Kojima, Rieko, Okumura, Masaki, Hagiwara, Masatoshi, Masui, Shoji, Maegawa, Ken-ichi, Saiki, Masatoshi, Horibe, Tomohisa, Suzuki, Mamoru, Inaba, Kenji
Published in Scientific reports (16.08.2013)
Published in Scientific reports (16.08.2013)
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RNA-seq analysis, targeted long-read sequencing and in silico prediction to unravel pathogenic intronic events and complicated splicing abnormalities in dystrophinopathy
Okubo, Mariko, Noguchi, Satoru, Awaya, Tomonari, Hosokawa, Motoyasu, Tsukui, Nobue, Ogawa, Megumu, Hayashi, Shinichiro, Komaki, Hirofumi, Mori-Yoshimura, Madoka, Oya, Yasushi, Takahashi, Yuji, Fukuyama, Tetsuhiro, Funato, Michinori, Hosokawa, Yousuke, Kinoshita, Satoru, Matsumura, Tsuyoshi, Nakamura, Sadao, Oshiro, Azusa, Terashima, Hiroshi, Nagasawa, Tetsuro, Sato, Tatsuharu, Shimada, Yumi, Tokita, Yasuko, Hagiwara, Masatoshi, Ogata, Katsuhisa, Nishino, Ichizo
Published in Human genetics (01.01.2023)
Published in Human genetics (01.01.2023)
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Journal Article
Application of the CDK9 inhibitor FIT-039 for the treatment of KSHV-associated malignancy
Sakamoto, Tetsunori, Ajiro, Masahiko, Watanabe, Akira, Matsushima, Shingo, Ueda, Keiji, Hagiwara, Masatoshi
Published in BMC cancer (20.01.2023)
Published in BMC cancer (20.01.2023)
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Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs
Suezawa, Takahiro, Kanagaki, Shuhei, Korogi, Yohei, Nakao, Kazuhisa, Hirai, Toyohiro, Murakami, Koji, Hagiwara, Masatoshi, Gotoh, Shimpei
Published in Respiratory research (04.11.2021)
Published in Respiratory research (04.11.2021)
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Rescue of recurrent deep intronic mutation underlying cell type-dependent quantitative NEMO deficiency
Boisson, Bertrand, Honda, Yoshitaka, Ajiro, Masahiko, Bustamante, Jacinta, Bendavid, Matthieu, Gennery, Andrew R, Kawasaki, Yuri, Ichishima, Jose, Osawa, Mitsujiro, Nihira, Hiroshi, Shiba, Takeshi, Tanaka, Takayuki, Chrabieh, Maya, Bigio, Benedetta, Hur, Hong, Itan, Yuval, Liang, Yupu, Okada, Satoshi, Izawa, Kazushi, Nishikomori, Ryuta, Ohara, Osamu, Heike, Toshio, Abel, Laurent, Puel, Anne, Saito, Megumu K, Casanova, Jean-Laurent, Hagiwara, Masatoshi, Yasumi, Takahiro
Published in The Journal of clinical investigation (01.02.2019)
Published in The Journal of clinical investigation (01.02.2019)
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In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids
Korogi, Yohei, Gotoh, Shimpei, Ikeo, Satoshi, Yamamoto, Yuki, Sone, Naoyuki, Tamai, Koji, Konishi, Satoshi, Nagasaki, Tadao, Matsumoto, Hisako, Ito, Isao, Chen-Yoshikawa, Toyofumi F., Date, Hiroshi, Hagiwara, Masatoshi, Asaka, Isao, Hotta, Akitsu, Mishima, Michiaki, Hirai, Toyohiro
Published in Stem cell reports (05.03.2019)
Published in Stem cell reports (05.03.2019)
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Journal Article
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth
Pozo, Natividad, Zahonero, Cristina, Fernández, Paloma, Liñares, Jose M, Ayuso, Angel, Hagiwara, Masatoshi, Pérez, Angel, Ricoy, Jose R, Hernández-Laín, Aurelio, Sepúlveda, Juan M, Sánchez-Gómez, Pilar
Published in The Journal of clinical investigation (01.06.2013)
Published in The Journal of clinical investigation (01.06.2013)
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S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
Toyomoto, Masayasu, Inoue, Asuka, Iida, Kei, Denawa, Masatsugu, Kii, Isao, Ngako Kadji, Francois Marie, Kishi, Takayuki, Im, Dohyun, Shimamura, Tatsuro, Onogi, Hiroshi, Yoshida, Suguru, Iwata, So, Aoki, Junken, Hosoya, Takamitsu, Hagiwara, Masatoshi
Published in Cell chemical biology (19.08.2021)
Published in Cell chemical biology (19.08.2021)
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Journal Article
Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain
Takeuchi, Akihide, Iida, Kei, Tsubota, Toshiaki, Hosokawa, Motoyasu, Denawa, Masatsugu, Brown, J.B., Ninomiya, Kensuke, Ito, Mikako, Kimura, Hiroshi, Abe, Takaya, Kiyonari, Hiroshi, Ohno, Kinji, Hagiwara, Masatoshi
Published in Cell reports (Cambridge) (01.05.2018)
Published in Cell reports (Cambridge) (01.05.2018)
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Journal Article
Leucettines, a Class of Potent Inhibitors of cdc2-Like Kinases and Dual Specificity, Tyrosine Phosphorylation Regulated Kinases Derived from the Marine Sponge Leucettamine B: Modulation of Alternative Pre-RNA Splicing
Debdab, Mansour, Carreaux, François, Renault, Steven, Soundararajan, Meera, Fedorov, Oleg, Filippakopoulos, Panagis, Lozach, Olivier, Babault, Lucie, Tahtouh, Tania, Baratte, Blandine, Ogawa, Yasushi, Hagiwara, Masatoshi, Eisenreich, Andreas, Rauch, Ursula, Knapp, Stefan, Meijer, Laurent, Bazureau, Jean-Pierre
Published in Journal of medicinal chemistry (23.06.2011)
Published in Journal of medicinal chemistry (23.06.2011)
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Visualization and genetic analysis of alternative splicing regulation in vivo using fluorescence reporters in transgenic Caenorhabditis elegans
Kuroyanagi, Hidehito, Hagiwara, Masatoshi, Ohno, Genta, Sakane, Hiroaki, Maruoka, Hiroyuki
Published in Nature protocols (01.09.2010)
Published in Nature protocols (01.09.2010)
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Integrated DNA methylation analysis reveals a potential role for ANKRD30B in Williams syndrome
Kimura, Ryo, Lardenoije, Roy, Tomiwa, Kiyotaka, Funabiki, Yasuko, Nakata, Masatoshi, Suzuki, Shiho, Awaya, Tomonari, Kato, Takeo, Okazaki, Shin, Murai, Toshiya, Heike, Toshio, Rutten, Bart P F, Hagiwara, Masatoshi
Published in Neuropsychopharmacology (New York, N.Y.) (01.09.2020)
Published in Neuropsychopharmacology (New York, N.Y.) (01.09.2020)
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