Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors
Miura, Hiromi, Quadros, Rolen M, Gurumurthy, Channabasavaiah B, Ohtsuka, Masato
Published in Nature protocols (01.01.2018)
Published in Nature protocols (01.01.2018)
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Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer
Nishina, Takashi, Deguchi, Yutaka, Ohshima, Daisuke, Takeda, Wakami, Ohtsuka, Masato, Shichino, Shigeyuki, Ueha, Satoshi, Yamazaki, Soh, Kawauchi, Mika, Nakamura, Eri, Nishiyama, Chiharu, Kojima, Yuko, Adachi-Akahane, Satomi, Hasegawa, Mizuho, Nakayama, Mizuho, Oshima, Masanobu, Yagita, Hideo, Shibuya, Kazutoshi, Mikami, Tetuo, Inohara, Naohiro, Matsushima, Kouji, Tada, Norihiro, Nakano, Hiroyasu
Published in Nature communications (16.04.2021)
Published in Nature communications (16.04.2021)
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Genetically modified mouse models to help fight COVID-19
Gurumurthy, Channabasavaiah B., Quadros, Rolen M., Richardson, Guy P., Poluektova, Larisa Y., Mansour, Suzanne L., Ohtsuka, Masato
Published in Nature protocols (01.12.2020)
Published in Nature protocols (01.12.2020)
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i-GONAD: a robust method for in situ germline genome engineering using CRISPR nucleases
Ohtsuka, Masato, Sato, Masahiro, Miura, Hiromi, Takabayashi, Shuji, Matsuyama, Makoto, Koyano, Takayuki, Arifin, Naomi, Nakamura, Shingo, Wada, Kenta, Gurumurthy, Channabasavaiah B
Published in Genome Biology (26.02.2018)
Published in Genome Biology (26.02.2018)
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Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins
Quadros, Rolen M, Miura, Hiromi, Harms, Donald W, Akatsuka, Hisako, Sato, Takehito, Aida, Tomomi, Redder, Ronald, Richardson, Guy P, Inagaki, Yutaka, Sakai, Daisuke, Buckley, Shannon M, Seshacharyulu, Parthasarathy, Batra, Surinder K, Behlke, Mark A, Zeiner, Sarah A, Jacobi, Ashley M, Izu, Yayoi, Thoreson, Wallace B, Urness, Lisa D, Mansour, Suzanne L, Ohtsuka, Masato, Gurumurthy, Channabasavaiah B
Published in Genome Biology (17.05.2017)
Published in Genome Biology (17.05.2017)
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Acrosin is essential for sperm penetration through the zona pellucida in hamsters
Hirose, Michiko, Honda, Arata, Fulka, Helena, Tamura-Nakano, Miwa, Matoba, Shogo, Tomishima, Toshiko, Mochida, Keiji, Hasegawa, Ayumi, Nagashima, Kiyoshi, Inoue, Kimiko, Ohtsuka, Masato, Baba, Tadashi, Yanagimachi, Ryuzo, Ogura, Atsuo
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2020)
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Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to in vivo-genome editing technology
Hasegawa, Ayumi, Mochida, Keiji, Nakamura, Ayaka, Miyagasako, Rico, Ohtsuka, Masato, Hatakeyama, Masahiko, Ogura, Atsuo
Published in Biology of reproduction (09.08.2022)
Published in Biology of reproduction (09.08.2022)
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Multiplexed genome editing by in vivo electroporation of Cas9 ribonucleoproteins effectively induces endometrial carcinoma in mice
Kobayashi, Ryosuke, Kawabata‐Iwakawa, Reika, Sugiyama, Makoto, Oyama, Tetsunari, Ohtsuka, Masato, Horii, Takuro, Morita, Sumiyo, Nishiyama, Masahiko, Hatada, Izuho
Published in International journal of cancer (01.06.2023)
Published in International journal of cancer (01.06.2023)
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i-GONAD (improved genome-editing via oviductal nucleic acids delivery), a convenient in vivo tool to produce genome-edited rats
Takabayashi, Shuji, Aoshima, Takuya, Kabashima, Katsuya, Aoto, Kazushi, Ohtsuka, Masato, Sato, Masahiro
Published in Scientific reports (13.08.2018)
Published in Scientific reports (13.08.2018)
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GONAD: A new method for germline genome editing in mice and rats
Namba, Masumi, Kobayashi, Tomoe, Koyano, Takayuki, Kohno, Mayumi, Ohtsuka, Masato, Matsuyama, Makoto
Published in Development, growth & differentiation (01.10.2021)
Published in Development, growth & differentiation (01.10.2021)
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GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice
Takahashi, Gou, Gurumurthy, Channabasavaiah B, Wada, Kenta, Miura, Hiromi, Sato, Masahiro, Ohtsuka, Masato
Published in Scientific reports (22.06.2015)
Published in Scientific reports (22.06.2015)
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Gender-Difference in Hair Length as Revealed by Crispr-Based Production of Long-Haired Mice with Dysfunctional FGF5 Mutations
Takahashi, Ryo, Takahashi, Gou, Kameyama, Yuichi, Sato, Masahiro, Ohtsuka, Masato, Wada, Kenta
Published in International journal of molecular sciences (06.10.2022)
Published in International journal of molecular sciences (06.10.2022)
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Abcb4-defect cholangitis mouse model with hydrophobic bile acid composition by in vivo liver-specific gene deletion
Tsuruya, Kota, Yokoyama, Keiko, Mishima, Yusuke, Ida, Kinuyo, Araki, Takuma, Ieda, Satsuki, Ohtsuka, Masato, Inagaki, Yutaka, Honda, Akira, Kagawa, Tatehiro, Kamiya, Akihide
Published in Journal of lipid research (01.09.2024)
Published in Journal of lipid research (01.09.2024)
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Indirect podocyte injury manifested in a partial podocytectomy mouse model
Okabe, Masahiro, Yamamoto, Kazuyoshi, Miyazaki, Yoichi, Motojima, Masaru, Ohtsuka, Masato, Pastan, Ira, Yokoo, Takashi, Matsusaka, Taiji
Published in American journal of physiology. Renal physiology (01.05.2021)
Published in American journal of physiology. Renal physiology (01.05.2021)
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Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes
Sato, Masahiro, Nakamura, Ayaka, Sekiguchi, Marie, Matsuwaki, Takashi, Miura, Hiromi, Gurumurthy, Channabasavaiah B, Kakuta, Shigeru, Ohtsuka, Masato
Published in Methods in molecular biology (Clifton, N.J.) (2023)
Published in Methods in molecular biology (Clifton, N.J.) (2023)
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Successful production of genome-edited rats by the rGONAD method
Kobayashi, Tomoe, Namba, Masumi, Koyano, Takayuki, Fukushima, Masaki, Sato, Masahiro, Ohtsuka, Masato, Matsuyama, Makoto
Published in BMC biotechnology (02.04.2018)
Published in BMC biotechnology (02.04.2018)
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CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice
Tanaka, Masayuki, Yokoyama, Keiko, Hayashi, Hideki, Isaki, Sanae, Kitatani, Kanae, Wang, Ting, Kawata, Hisako, Matsuzawa, Hideyuki, Gurumurthy, Channabasavaiah B, Miura, Hiromi, Ohtsuka, Masato
Published in Genome Biology (25.10.2022)
Published in Genome Biology (25.10.2022)
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