TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model
Cubero, F J, Singh, A, Borkham-Kamphorst, E, Nevzorova, Y A, Al Masaoudi, M, Haas, U, Boekschoten, M V, Gassler, N, Weiskirchen, R, Muller, M, Liedtke, C, Trautwein, C
Published in Cell death and differentiation (01.11.2013)
Published in Cell death and differentiation (01.11.2013)
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Journal Article
Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model
Hatting, M, Spannbauer, M, Peng, J, Al Masaoudi, M, Sellge, G, Nevzorova, Y A, Gassler, N, Liedtke, C, Cubero, F J, Trautwein, C
Published in Cell death & disease (05.03.2015)
Published in Cell death & disease (05.03.2015)
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Journal Article
P356 CREMa TRANSGENE-ASSOCIATED IMMUNE RESPONSE INHIBITS THE PROGRESSION OF CHRONIC INFLAMMATORY LIVER DISEASE
Hermanns, N, Cubero, F.J, Mohs, A, Ohl, K, Al Masaoudi, M, Tenbrock, K, Trautwein, C
Published in Journal of hepatology (01.04.2014)
Published in Journal of hepatology (01.04.2014)
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Journal Article
P1084 : Compound function of Jnk1 and Jnk2 in hepatocytes is protective in acetaminophen-induced liver injury
Cubero, F.J, Hu, W, Zhao, G, Peng, J, Nevzorova, Y.A, Al Masaoudi, M, Bechmann, L.P, Boekschoten, M.V, Muller, M, Gassler, N, Canbay, A.E, Liedtke, C, Trautwein, C
Published in Journal of hepatology (01.04.2015)
Published in Journal of hepatology (01.04.2015)
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Journal Article
P0255 : Disruption of the GP130 signaling pathway in hepatocytes attenuates hepatocarcinogenesis
Cubero, F.J, Hatting, M, Spannbauer, M, Peng, J, Al Masaoudi, M, Sellge, G, Nevzorova, Y.A, Gassler, N, Liedtke, C, Trautwein, C
Published in Journal of hepatology (01.04.2015)
Published in Journal of hepatology (01.04.2015)
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Journal Article
O145 THE REGULATORY INTERPLAY BETWEEN JNK1 AND JNK2 IS A SINE QUA NON CONDITION AGAINST DRUG-INDUCED LIVER TOXICITY
Cubero, F.J, Hu, W, Zhao, G, Peng, J, Nevzorova, Y.A, Al Masaoudi, M, Boekschoten, M.V, Muller, M, Gassler, N, Weiskirchen, R, Davis, R.J, Liedtke, C, Trautwein, C
Published in Journal of hepatology (01.04.2014)
Published in Journal of hepatology (01.04.2014)
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Journal Article
O96 HEMATOPOIETIC CELLS-DERIVED JNK1 DRIVES HEPATIC INJURY AND HEPATOCELLULAR CARCINOMA IN IKKg/NEMO-DELETED LIVERS
Cubero, F.J, Zhao, G, Nevzorova, Y.A, Al Masaoudi, M, Verdier, J, Peng, J, Schaefer, F.M, Hatting, M, Hermanns, N, Boekschoten, M.V, Grouls, C, Gassler, N, Kiessling, F, Muller, M, Davis, R.J, Liedtke, C, Trautwein, C
Published in Journal of hepatology (01.04.2014)
Published in Journal of hepatology (01.04.2014)
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Journal Article
1037 DISRUPTION OF THE INTERPLAY BETWEEN IKKg/NEMO AND Jnk1 EXACERBATES CHRONIC LIVER DISEASE AND HCC THROUGH ALTERATION OF THE MAPK PATHWAY
Cubero, F.J, Zhao, G, Nevzorova, Y.A, Al Masaoudi, M, Hatting, M, Schaefer, F, Hermanns, N, Gassler, N, Liedtke, C, Trautwein, C
Published in Journal of hepatology (01.04.2013)
Published in Journal of hepatology (01.04.2013)
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Journal Article
137 TNF-RECEPTOR 1-DEPENDENT SIGNALLING DETERMINES THE PROGRESSION OF NEMO-MEDIATED HEPATITIS
Singh, A, Cubero, F.J, Borkham-Kamphorst, E, Al-Masaoudi, M, Liedtke, C, Luedde, T, Weiskirchen, R, Heikenwälder, M, Trautwein, C
Published in Journal of hepatology (01.03.2011)
Published in Journal of hepatology (01.03.2011)
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Journal Article
Hepatocyte caspase‐8 is an essential modulator of steatohepatitis in rodents
Hatting, Maximilian, Zhao, Gang, Schumacher, Fabienne, Sellge, Gernot, Al Masaoudi, Malika, Gaβler, Nikolaus, Boekschoten, Mark, Müller, Michael, Liedtke, Christian, Cubero, Francisco Javier, Trautwein, Christian
Published in Hepatology (Baltimore, Md.) (01.06.2013)
Published in Hepatology (Baltimore, Md.) (01.06.2013)
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Journal Article
Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury
Cubero, Francisco Javier, Zhao, Gang, Nevzorova, Yulia A, Hatting, Maximilian, Al Masaoudi, Malika, Verdier, Julien, Peng, Jin, Schaefer, Frederik M, Hermanns, Nadine, Boekschoten, Mark V, Grouls, Christoph, Gassler, Nikolaus, Kiessling, Fabian, Muller, Michael, Davis, Roger J, Liedtke, Christian, Trautwein, Christian
Published in Journal of hepatology (01.01.2015)
Published in Journal of hepatology (01.01.2015)
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Journal Article
TNFR1 determines progression of chronic liver injury in the IKK[gamma]/Nemo genetic model
Cubero, F J, Singh, A, Borkham-kamphorst, E, Nevzorova, Y A, Al Masaoudi, M, Haas, U, Boekschoten, M V, Gassler, N, Weiskirchen, R, Muller, M, Liedtke, C, Trautwein, C
Published in Cell death and differentiation (01.11.2013)
Published in Cell death and differentiation (01.11.2013)
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Journal Article
4 DIFFERENT ROLES OF JNK1 AND JNK2 IN THE DEVELOPMENT OF NASH AND HCC
Cubero, F.J, Zhao, G, Nevzorova, Y.A, Hatting, M, Drvarov, O, Masaoudi, M. Al, Gassler, N, Liedtke, C, Trautwein, C
Published in Journal of hepatology (01.04.2012)
Published in Journal of hepatology (01.04.2012)
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Journal Article
Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model
Cubero, FJ, Hatting, M, Spannbauer, M, Peng, J, Hu, W, Al Masaoudi, M, Sellge, G, Gassler, N, Liedtke, C, Trautwein, C
Published in Zeitschrift für Gastroenterologie (16.01.2015)
Published in Zeitschrift für Gastroenterologie (16.01.2015)
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Conference Proceeding
TRAIL and TNFR1-dependent pathways and their role for progression of Nemo-dependent hepatitis
Singh, A, Cubero, FJ, Borkham-Kamphorst, E, Al-Masaoudi, M, Liedtke, C, Luedde, T, Weiskirchen, R, Heikenwälder, M, Trautwein, C
Published in Zeitschrift für Gastroenterologie (13.01.2011)
Published in Zeitschrift für Gastroenterologie (13.01.2011)
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Conference Proceeding
Impaired hepatocyte priming contributes to dysregulated proliferation and leads to death during liver regeneration in conditional NEMO ko mice
Malato, Y, Beraza, N, Al-Masaoudi, M, Liedtke, C, Trautwein, C
Published in Zeitschrift für Gastroenterologie (20.01.2009)
Published in Zeitschrift für Gastroenterologie (20.01.2009)
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Conference Proceeding
Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers
Cubero, FJ, Zhao, G, Nevzorova, YA, Al Masaoudi, M, Verdier, J, Peng, J, Schaefer, F, Hatting, M, Hermanns, N, Boekschoten, MV, Grouls, C, Gassler, N, Kiessling, F, Muller, M, Liedtke, C, Trautwein, C
Published in Zeitschrift für Gastroenterologie (13.01.2014)
Published in Zeitschrift für Gastroenterologie (13.01.2014)
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Conference Proceeding
Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity
Cubero, FJ, Zhao, G, Hu, W, Peng, J, Nevzorova, YA, Al Masaoudi, M, Boekschoten, MV, Muller, M, Gassler, N, Weiskirchen, R, Trautwein, C
Published in Zeitschrift für Gastroenterologie (13.01.2014)
Published in Zeitschrift für Gastroenterologie (13.01.2014)
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Conference Proceeding
IKK2 hepatocyte specific deletion alters cell cycle progression during liver regeneration
Malato, Y, Beraza, N, Al-masaoudi, M, Pasparakis, M, Trautwein, C
Published in Zeitschrift für Gastroenterologie (05.09.2007)
Published in Zeitschrift für Gastroenterologie (05.09.2007)
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Conference Proceeding