Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice
Tahara, Atsuo, Kurosaki, Eiji, Yokono, Masanori, Yamajuku, Daisuke, Kihara, Rumi, Hayashizaki, Yuka, Takasu, Toshiyuki, Imamura, Masakazu, Li, Qun, Tomiyama, Hiroshi, Kobayashi, Yoshinori, Noda, Atsushi, Sasamata, Masao, Shibasaki, Masayuki
Published in European journal of pharmacology (05.09.2013)
Published in European journal of pharmacology (05.09.2013)
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Broad spectrum and potent antitumor activities of YM155, a novel small‐molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models
Nakahara, Takahito, Kita, Aya, Yamanaka, Kentaro, Mori, Masamichi, Amino, Nobuaki, Takeuchi, Masahiro, Tominaga, Fumiko, Kinoyama, Isao, Matsuhisa, Akira, Kudou, Masafumi, Sasamata, Masao
Published in Cancer science (01.03.2011)
Published in Cancer science (01.03.2011)
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SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats
Yokono, Masanori, Takasu, Toshiyuki, Hayashizaki, Yuka, Mitsuoka, Keisuke, Kihara, Rumi, Muramatsu, Yuko, Miyoshi, Sousuke, Tahara, Atsuo, Kurosaki, Eiji, Li, Qun, Tomiyama, Hiroshi, Sasamata, Masao, Shibasaki, Masayuki, Uchiyama, Yasuo
Published in European journal of pharmacology (15.03.2014)
Published in European journal of pharmacology (15.03.2014)
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YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts
NAKAHARA, Takahito, TAKEUCHI, Masahiro, SASAMATA, Masao, KINOYAMA, Isao, MINEMATSU, Tsuyoshi, SHIRASUNA, Kenna, MATSUHISA, Akira, KITA, Aya, TOMINAGA, Fumiko, YAMANAKA, Kentaro, KUDOH, Masafumi
Published in Cancer research (Chicago, Ill.) (01.09.2007)
Published in Cancer research (Chicago, Ill.) (01.09.2007)
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Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats
Tahara, Atsuo, Kurosaki, Eiji, Yokono, Masanori, Yamajuku, Daisuke, Kihara, Rumi, Hayashizaki, Yuka, Takasu, Toshiyuki, Imamura, Masakazu, Li, Qun, Tomiyama, Hiroshi, Kobayashi, Yoshinori, Noda, Atsushi, Sasamata, Masao, Shibasaki, Masayuki
Published in Journal of pharmacy and pharmacology (01.07.2014)
Published in Journal of pharmacy and pharmacology (01.07.2014)
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Pharmacological profile of ipragliflozin (ASP1941), a novel selective SGLT2 inhibitor, in vitro and in vivo
Tahara, Atsuo, Kurosaki, Eiji, Yokono, Masanori, Yamajuku, Daisuke, Kihara, Rumi, Hayashizaki, Yuka, Takasu, Toshiyuki, Imamura, Masakazu, Qun, Li, Tomiyama, Hiroshi, Kobayashi, Yoshinori, Noda, Atsushi, Sasamata, Masao, Shibasaki, Masayuki
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.04.2012)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.04.2012)
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Antidiabetic Effects of SGLT2-Selective Inhibitor Ipragliflozin in Streptozotocin–Nicotinamide-Induced Mildly Diabetic Mice
Tahara, Atsuo, Kurosaki, Eiji, Yokono, Masanori, Yamajuku, Daisuke, Kihara, Rumi, Hayashizaki, Yuka, Takasu, Toshiyuki, Imamura, Masakazu, Qun, Li, Tomiyama, Hiroshi, Kobayashi, Yoshinori, Noda, Atsushi, Sasamata, Masao, Shibasaki, Masayuki
Published in Journal of Pharmacological Sciences (2012)
Published in Journal of Pharmacological Sciences (2012)
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Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin
Nakamura, Naoto, Yamauchi, Tomohiro, Hiramoto, Masashi, Yuri, Masatoshi, Naito, Masanori, Takeuchi, Masahiro, Yamanaka, Kentaro, Kita, Aya, Nakahara, Takahito, Kinoyama, Isao, Matsuhisa, Akira, Kaneko, Naoki, Koutoku, Hiroshi, Sasamata, Masao, Yokota, Hiroyuki, Kawabata, Shigeki, Furuichi, Kiyoshi
Published in Molecular & cellular proteomics (01.07.2012)
Published in Molecular & cellular proteomics (01.07.2012)
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In vitro and in vivo pharmacological profile of the selective β3-adrenoceptor agonist mirabegron in rats
Hatanaka, Toshiki, Ukai, Masashi, Watanabe, Mai, Someya, Akiyoshi, Ohtake, Akiyoshi, Suzuki, Masanori, Ueshima, Koji, Sato, Shuichi, Sasamata, Masao
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.03.2013)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.03.2013)
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Effect of Tamsulosin on Bladder Blood Flow and Bladder Function in a Rat Model of Bladder Over Distention/Emptying Induced Bladder Overactivity
Okutsu, Hiroko, Matsumoto, Seiji, Ohtake, Akiyoshi, Suzuki, Masanori, Sato, Shuichi, Sasamata, Masao, Uemura, Hirotsugu
Published in The Journal of urology (01.12.2011)
Published in The Journal of urology (01.12.2011)
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The Forefront for Novel Therapeutic Agents Based on the Pathophysiology of Lower Urinary Tract Dysfunction: Ameliorative Effect of Solifenacin Succinate (Vesicare ®), a Bladder-Selective Antimuscarinic Agent, on Overactive Bladder Symptoms, Especially Urgency Episodes
Ohtake, Akiyoshi, Sato, Shuichi, Sasamata, Masao, Miyata, Keiji
Published in Journal of Pharmacological Sciences (2010)
Published in Journal of Pharmacological Sciences (2010)
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Pharmacological Characterization of a New Antimuscarinic Agent, Solifenacin Succinate, in Comparison with Other Antimuscarinic Agents
Ohtake, Akiyoshi, Saitoh, Chikashi, Yuyama, Hironori, Ukai, Masashi, Okutsu, Hiroko, Noguchi, Yukiko, Hatanaka, Toshiki, Suzuki, Masanori, Sato, Shuichi, Sasamata, Masao, Miyata, Keiji
Published in Biological & pharmaceutical bulletin (2007)
Published in Biological & pharmaceutical bulletin (2007)
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Journal Article
In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats
OHTAKE, Akiyoshi, UKAI, Masashi, HATANAKA, Toshiki, KOBAYASHI, Seiji, IKEDA, Ken, SATO, Shuichi, MIYATA, Keiji, SASAMATA, Masao
Published in European journal of pharmacology (25.05.2004)
Published in European journal of pharmacology (25.05.2004)
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Journal Article
Neuronal Nitric Oxide Synthase Activation and Peroxynitrite Formation in Ischemic Stroke Linked to Neural Damage
Eliasson, Mikael J. L, Huang, Zhihong, Ferrante, Robert J, Sasamata, Masao, Molliver, Mark E, Snyder, Solomon H, Moskowitz, Michael A
Published in The Journal of neuroscience (15.07.1999)
Published in The Journal of neuroscience (15.07.1999)
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Effect of Tamsulosin on Bladder Microcirculation in a Rat Ischemia-reperfusion Model, Evaluated by Pencil Lens Charge-coupled Device Microscopy System
Mizuno, Hideki, Yamamoto, Tokunori, Okutsu, Hiroko, Ohtake, Akiyoshi, Sasamata, Masao, Matsukawa, Yoshihisa, Funahashi, Yasuhito, Kato, Masashi, Hattori, Ryohei, Gotoh, Momokazu
Published in Urology (Ridgewood, N.J.) (01.11.2010)
Published in Urology (Ridgewood, N.J.) (01.11.2010)
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Journal Article
New Topics in Vasopressin Receptors and Approach to Novel Drugs: Research and Development of Conivaptan Hydrochloride (YM087), a Drug for the Treatment of Hyponatremia
Arai, Yukinori, Fujimori, Akira, Sasamata, Masao, Miyata, Keiji
Published in Journal of Pharmacological Sciences (01.01.2009)
Published in Journal of Pharmacological Sciences (01.01.2009)
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Minodronic acid, a third-generation bisphosphonate, antagonizes purinergic P2X2/3 receptor function and exerts an analgesic effect in pain models
Kakimoto, Shuichiro, Nagakura, Yukinori, Tamura, Seiji, Watabiki, Tomonari, Shibasaki, Kumiko, Tanaka, Shohei, Mori, Masamichi, Sasamata, Masao, Okada, Masamichi
Published in European journal of pharmacology (28.07.2008)
Published in European journal of pharmacology (28.07.2008)
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Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats
Funatsu, Toshiyuki, Takeuchi, Asako, Hirata, Takuya, Keto, Yoshihiro, Akuzawa, Shinobu, Sasamata, Masao
Published in European journal of pharmacology (14.11.2007)
Published in European journal of pharmacology (14.11.2007)
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