Topiramate: preclinical evaluation of structurally novel anticonvulsant
Shank, R P, Gardocki, J F, Vaught, J L, Davis, C B, Schupsky, J J, Raffa, R B, Dodgson, S J, Nortey, S O, Maryanoff, B E
Published in Epilepsia (Copenhagen) (01.03.1994)
Published in Epilepsia (Copenhagen) (01.03.1994)
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Structure−Activity Studies on Anticonvulsant Sugar Sulfamates Related to Topiramate. Enhanced Potency with Cyclic Sulfate Derivatives
Maryanoff, Bruce E., Costanzo, Michael J., Nortey, Samuel O., Greco, Michael N., Shank, Richard P., Schupsky, James J., Ortegon, Marta P., Vaught, Jeffry L.
Published in Journal of medicinal chemistry (09.04.1998)
Published in Journal of medicinal chemistry (09.04.1998)
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Discovery and Optimization of a Novel Series of Thrombin Receptor (PAR-1) Antagonists: Potent, Selective Peptide Mimetics Based on Indole and Indazole Templates
Zhang, Han-Cheng, Derian, Claudia K, Andrade-Gordon, Patricia, Hoekstra, William J, McComsey, David F, White, Kimberly B, Poulter, Brenda L, Addo, Michael F, Cheung, Wai-Man, Damiano, Bruce P, Oksenberg, Donna, Reynolds, Elwood E, Pandey, Anjali, Scarborough, Robert M, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (29.03.2001)
Published in Journal of medicinal chemistry (29.03.2001)
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Metabolism and excretion of the antiepileptic/antimigraine drug, topiramate in animals and humans
CALDWELL, G. W, WU, W. N, MASUCCI, J. A, MCKOWN, L. A, GAUTHIER, D, JONES, W. J, LEO, G. C, MARYANOFF, B. E
Published in European journal of drug metabolism and pharmacokinetics (01.07.2005)
Published in European journal of drug metabolism and pharmacokinetics (01.07.2005)
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Molecular Basis for the Inhibition of Human α-Thrombin by the Macrocyclic Peptide Cyclotheonamide A
Maryanoff, Bruce E., Qiu, Xiayang, Padmanabhan, K. P., Tulinsky, Alexander, Almond, Harold R., Andrade-Gordon, Patricia, Greco, Michael N., Kauffman, Jack A., Nicolaou, K. C., Liu, Aijn, Brungs, Peter H., Fusetani, Nobuhiro
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1993)
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Potent Thrombin Inhibitors That Probe the S1‘ Subsite: Tripeptide Transition State Analogues Based on a Heterocycle-Activated Carbonyl Group
Costanzo, Michael J, Maryanoff, Bruce E, Hecker, Leonard R, Schott, Mary R, Yabut, Stephen C, Zhang, Han-Cheng, Andrade-Gordon, Patricia, Kauffman, Jack A, Lewis, Joan M, Krishnan, Raman, Tulinsky, Alexander
Published in Journal of medicinal chemistry (02.08.1996)
Published in Journal of medicinal chemistry (02.08.1996)
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Potential anxiolytic agents. 3. Novel A-ring modified pyrido[1,2- a]benzimidazoles
Maryanoff, Bruce E., Nortey, Samuel O., McNally, James J., Sanfilippo, Pauline J., McComsey, David F., Dubinsky, Barry, Shank, Richard P., Reitz, Allen B.
Published in Bioorganic & medicinal chemistry letters (07.06.1999)
Published in Bioorganic & medicinal chemistry letters (07.06.1999)
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Thrombin receptor-activating peptides (TRAPs): Investigation of bioactive conformations via structure–activity, spectroscopic, and computational studies
Ceruso, Marco A., McComsey, David F., Leo, Gregory C., Andrade-Gordon, Patricia, Addo, Michael F., Scarborough, Robert M., Oksenberg, Donna, Maryanoff, Bruce E.
Published in Bioorganic & medicinal chemistry (01.11.1999)
Published in Bioorganic & medicinal chemistry (01.11.1999)
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McN-5652: a highly potent inhibitor of serotonin uptake
SHANK, R. P, VAUGHT, J. L, PELLEY, K. A, SETLER, P. E, MCCOMSEY, D. F, MARYANOFF, B. E
Published in The Journal of pharmacology and experimental therapeutics (01.12.1988)
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Published in The Journal of pharmacology and experimental therapeutics (01.12.1988)
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Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists of the thrombin receptor (PAR-1)
McComsey, David F., Hawkins, Michael J., Andrade-Gordon, Patricia, Addo, Michael F., Oksenberg, Donna, Maryanoff, Bruce E.
Published in Bioorganic & medicinal chemistry letters (17.05.1999)
Published in Bioorganic & medicinal chemistry letters (17.05.1999)
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Thrombin receptor (PAR-1) antagonists. Heterocycle-based peptidomimetics of the SFLLR agonist motif
Hoekstra, William J., Hulshizer, Becky L., McComsey, David F., Andrade-Gordon, Patricia, Kauffman, Jack A., Addo, Michael F., Oksenberg, Donna, Scarborough, Robert M., Maryanoff, Bruce E.
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
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Carbohydrate biguanides as potential hypoglycemic agents
Reitz, Allen B, Tuman, Robert W, Marchione, Carol S, Jordan, Alfonzo D, Bowden, Charles R, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (01.09.1989)
Published in Journal of medicinal chemistry (01.09.1989)
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Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-.beta.-D-fructopyranose sulfamate and related compounds
Maryanoff, Bruce E, Nortey, Samuel O, Gardocki, Joseph F, Shank, Richard P, Dodgson, Susanna P
Published in Journal of medicinal chemistry (01.05.1987)
Published in Journal of medicinal chemistry (01.05.1987)
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Administration of a Potent Antagonist of Protease-Activated Receptor-1 (PAR-1) Attenuates Vascular Restenosis Following Balloon Angioplasty in Rats
Andrade-Gordon, P, Derian, C K, Maryanoff, B E, Zhang, H C, Addo, M F, Cheung Wm, Damiano, B P, D'Andrea, M R, Darrow, A L, de Garavilla, L, Eckardt, A J, Giardino, E C, Haertlein, B J, McComsey, D F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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