Antipsychotic profiles of TASP0443294, a novel and orally active positive allosteric modulator of metabotropic glutamate 2 receptor
Hikichi, Hirohiko, Hiyoshi, Tetsuaki, Marumo, Toshiyuki, Tomishima, Yasumitsu, Kaku, Ayaka, Iida, Izumi, Urabe, Hiroki, Tamita, Tomoko, Yasuhara, Akito, Karasawa, Jun-ichi, Chaki, Shigeyuki
Published in Journal of pharmacological sciences (01.03.2015)
Published in Journal of pharmacological sciences (01.03.2015)
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The inhibitor of 20‐HETE synthesis, TS‐011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice
Marumo, Toshiyuki, Eto, Kei, Wake, Hiroaki, Omura, Tomohiro, Nabekura, Junichi
Published in British journal of pharmacology (01.11.2010)
Published in British journal of pharmacology (01.11.2010)
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Evaluation of the Safety, Tolerability, and Pharmacokinetic Profiles of TP0473292 (TS-161), A Prodrug of a Novel Orthosteric mGlu2/3 Receptor Antagonist TP0178894, in Healthy Subjects and Its Antidepressant-Like Effects in Rodents
Watanabe, Mai, Marcy, Brian, Hiroki, Ayano, Watase, Hirotaka, Kinoshita, Kohnosuke, Iijima, Michihiko, Marumo, Toshiyuki, Zarate, Carlos A, Chaki, Shigeyuki
Published in The international journal of neuropsychopharmacology (11.02.2022)
Published in The international journal of neuropsychopharmacology (11.02.2022)
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A Novel Potent and Selective Histamine H 3 Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, and Wake-Promoting and Procognitive Effects in Rodents
Hino, Noriko, Marumo, Toshiyuki, Kotani, Makiko, Shimazaki, Toshiharu, Kaku-Fukumoto, Ayaka, Hikichi, Hirohiko, Karasawa, Jun-Ichi, Tomishima, Yasumitsu, Komiyama, Hiroko, Tatsuda, Emi, Nozawa, Dai, Nakamura, Toshio, Chaki, Shigeyuki
Published in The Journal of pharmacology and experimental therapeutics (01.11.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2020)
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Discovery of MGS0274, an ester prodrug of a metabotropic glutamate receptor 2/3 agonist with improved oral bioavailability
Urabe, Hiroki, Miyakoshi, Naoki, Ohtake, Norikazu, Nozoe, Akiko, Ochi, Motoki, Fukasawa, Misako, Kinoshita, Kohnosuke, Yamaguchi, Jun-ichi, Marumo, Toshiyuki, Hikichi, Hirohiko, Chaki, Shigeyuki, Hashihayata, Takashi
Published in European journal of medicinal chemistry (01.10.2020)
Published in European journal of medicinal chemistry (01.10.2020)
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Neurophysiologic and antipsychotic profiles of TASP0433864, a novel positive allosteric modulator of metabotropic glutamate 2 receptor
Hiyoshi, Tetsuaki, Marumo, Toshiyuki, Hikichi, Hirohiko, Tomishima, Yasumitsu, Urabe, Hiroki, Tamita, Tomoko, Iida, Izumi, Yasuhara, Akito, Karasawa, Jun-ichi, Chaki, Shigeyuki
Published in The Journal of pharmacology and experimental therapeutics (01.12.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2014)
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Increase of 20-HETE Synthase after Brain Ischemia in Rats Revealed by PET Study with 11 C-Labeled 20-HETE Synthase-Specific Inhibitor
Kawasaki, Toshiyuki, Marumo, Toshiyuki, Shirakami, Keiko, Mori, Tomoko, Doi, Hisashi, Suzuki, Masaaki, Watanabe, Yasuyoshi, Chaki, Shigeyuki, Nakazato, Atsuro, Ago, Yukio, Hashimoto, Hitoshi, Matsuda, Toshio, Baba, Akemichi, Onoe, Hirotaka
Published in Journal of cerebral blood flow and metabolism (01.09.2012)
Published in Journal of cerebral blood flow and metabolism (01.09.2012)
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Relationship between cerebrospinal and peripheral S100B levels after focal cerebral ischemia in rats
Tanaka, Yu, Marumo, Toshiyuki, Omura, Tomohiro, Yoshida, Shigeru
Published in Neuroscience letters (02.05.2008)
Published in Neuroscience letters (02.05.2008)
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Early increases in serum S100B are associated with cerebral hemorrhage in a rat model of focal cerebral ischemia
Tanaka, Yu, Marumo, Toshiyuki, Omura, Tomohiro, Yoshida, Shigeru
Published in Brain research (28.08.2008)
Published in Brain research (28.08.2008)
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Increase of 20-HETE Synthase after Brain Ischemia in Rats Revealed by PET Study with 11C-Labeled 20-HETE Synthase-Specific Inhibitor
Kawasaki, Toshiyuki, Marumo, Toshiyuki, Shirakami, Keiko, Mori, Tomoko, Doi, Hisashi, Suzuki, Masaaki, Watanabe, Yasuyoshi, Chaki, Shigeyuki, Nakazato, Atsuro, Ago, Yukio, Hashimoto, Hitoshi, Matsuda, Toshio, Baba, Akemichi, Onoe, Hirotaka
Published in Journal of cerebral blood flow and metabolism (01.09.2012)
Published in Journal of cerebral blood flow and metabolism (01.09.2012)
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Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with super(11)C-labeled 20-HETE synthase-specific inhibitor
Kawasaki, Toshiyuki, Marumo, Toshiyuki, Shirakami, Keiko, Mori, Tomoko, Doi, Hisashi, Suzuki, Masaaki, Watanabe, Yasuyoshi, Chaki, Shigeyuki, Nakazato, Atsuro, Ago, Yukio, Hashimoto, Hitoshi, Matsuda, Toshio, Baba, Akemichi, Onoe, Hirotaka
Published in Journal of cerebral blood flow and metabolism (01.09.2012)
Published in Journal of cerebral blood flow and metabolism (01.09.2012)
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