Selenium-Containing Chrysin and Quercetin Derivatives: Attractive Scaffolds for Cancer Therapy
Martins, Inês L, Charneira, Catarina, Gandin, Valentina, Ferreira da Silva, João L, Justino, Gonçalo C, Telo, João P, Vieira, Abel J. S. C, Marzano, Cristina, Antunes, Alexandra M. M
Published in Journal of medicinal chemistry (28.05.2015)
Published in Journal of medicinal chemistry (28.05.2015)
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Journal Article
Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine
Harjivan, Shrika G, Charneira, Catarina, Martins, Inês L, Pereira, Sofia A, Espadas, Guadalupe, Sabidó, Eduard, Beland, Frederick A, Marques, M Matilde, Antunes, Alexandra M M
Published in Molecules (Basel, Switzerland) (03.03.2021)
Published in Molecules (Basel, Switzerland) (03.03.2021)
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Journal Article
Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study
Pinheiro, Pedro F., Pereira, Sofia A., Harjivan, Shrika G., Martins, Inês L., Marinho, Aline T., Cipriano, Madalena, Jacob, Cristina C., Oliveira, Nuno G., Castro, Matilde F., Marques, M. Matilde, Antunes, Alexandra M. M., Miranda, Joana P.
Published in Archives of toxicology (01.03.2017)
Published in Archives of toxicology (01.03.2017)
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Journal Article
The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals
Martins, Inês L., Nunes, João, Charneira, Catarina, Morello, Judit, Pereira, Sofia A., Telo, João P., Marques, M. Matilde, Antunes, Alexandra M.M.
Published in Free radical biology & medicine (01.12.2018)
Published in Free radical biology & medicine (01.12.2018)
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Journal Article
New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan
Nunes, João, Martins, Inês L., Charneira, Catarina, Pogribny, Igor P., de Conti, Aline, Beland, Frederick A., Marques, M. Matilde, Jacob, Cristina C., Antunes, Alexandra M.M.
Published in Toxicology letters (15.12.2016)
Published in Toxicology letters (15.12.2016)
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Journal Article
Protein Adducts As Prospective Biomarkers of Nevirapine Toxicity
Antunes, Alexandra M. M, Godinho, Ana L. A, Martins, Inês L, Oliveira, M. Conceição, Gomes, Ricardo A, Coelho, Ana V, Beland, Frederick A, Marques, M. Matilde
Published in Chemical research in toxicology (15.11.2010)
Published in Chemical research in toxicology (15.11.2010)
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Journal Article
Synthesis and biological activity of 6-selenocaffeine: potential modulator of chemotherapeutic drugs in breast cancer cells
Martins, Inês L, Miranda, Joana P, Oliveira, Nuno G, Fernandes, Ana S, Gonçalves, Sandrina, Antunes, Alexandra M M
Published in Molecules (Basel, Switzerland) (08.05.2013)
Published in Molecules (Basel, Switzerland) (08.05.2013)
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Journal Article
Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy
Valentim-Coelho, Cristina, Vaz, Fátima, Antunes, Marília, Neves, Sofia, Martins, Inês L, Osório, Hugo, Feliciano, Amélia, Pinto, Paula, Bárbara, Cristina, Penque, Deborah
Published in Antioxidants (26.11.2020)
Published in Antioxidants (26.11.2020)
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Journal Article
Amino Acid Adduct Formation by the Nevirapine Metabolite, 12-HydroxynevirapineA Possible Factor in Nevirapine Toxicity
Antunes, Alexandra M. M, Godinho, Ana L. A, Martins, Inês L, Justino, Gonçalo C, Beland, Frederick A, Marques, M. Matilde
Published in Chemical research in toxicology (17.05.2010)
Published in Chemical research in toxicology (17.05.2010)
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Journal Article
Quinoid derivatives of the nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine: activation pathway to amino acid adducts
Harjivan, Shrika G., Pinheiro, Pedro F., Martins, Inês L., Godinho, Ana L., Wanke, Riccardo, Santos, Pedro P., Pereira, Sofia A., Beland, Frederick A., Marques, M. Matilde, Antunes, Alexandra M. M.
Published in Toxicology research (Cambridge) (01.01.2015)
Published in Toxicology research (Cambridge) (01.01.2015)
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Journal Article
High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches
Godinho, Ana L.A., Martins, Inês L., Nunes, João, Charneira, Catarina, Grilo, Jorge, Silva, Diogo M., Pereira, Sofia A., Soto, Karina, Oliveira, M. Conceição, Marques, M. Matilde, Jacob, Cristina C., Antunes, Alexandra M.M.
Published in European journal of pharmaceutical sciences (01.07.2018)
Published in European journal of pharmaceutical sciences (01.07.2018)
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Journal Article
Toxic events induced by the antiepileptic drug carbamazepine: Is bioactivation really involved?
Antunes, Alexandra M.M., Martins, Inês L., Telo, J. Paulo, Marques, M. Matilde
Published in Toxicology letters (20.10.2017)
Published in Toxicology letters (20.10.2017)
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Journal Article
Quinoid derivatives of the nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine: activation pathway to amino acid adductsElectronic supplementary information (ESI) available. See DOI: 10.1039/c5tx00176e
Harjivan, Shrika G, Pinheiro, Pedro F, Martins, Inês L, Godinho, Ana L, Wanke, Riccardo, Santos, Pedro P, Pereira, Sofia A, Beland, Frederick A, Marques, M. Matilde, Antunes, Alexandra M. M
Year of Publication 19.10.2015
Year of Publication 19.10.2015
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Journal Article