Liver‐specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice
Ko, Kwang Suk, Tomasi, Maria Lauda, Iglesias‐Ara, Ainhoa, French, Barbara A., French, Samuel W., Ramani, Komal, Lozano, Juan José, Oh, Pilsoo, He, Lina, Stiles, Bangyan L, Li, Tony W.H, Yang, Heping, Martínez‐Chantar, M. Luz, Mato, José M., Lu, Shelly C.
Published in Hepatology (Baltimore, Md.) (01.12.2010)
Published in Hepatology (Baltimore, Md.) (01.12.2010)
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Systems biology for hepatologists
Mato, José M., Martínez‐Chantar, M. Luz, Lu, Shelly C.
Published in Hepatology (Baltimore, Md.) (01.08.2014)
Published in Hepatology (Baltimore, Md.) (01.08.2014)
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Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect
Lara, E, Mai, A, Calvanese, V, Altucci, L, Lopez-Nieva, P, Martinez-Chantar, M L, Varela-Rey, M, Rotili, D, Nebbioso, A, Ropero, S, Montoya, G, Oyarzabal, J, Velasco, S, Serrano, M, Witt, M, Villar-Garea, A, Inhof, A, Mato, J M, Esteller, M, Fraga, M F
Published in Oncogene (12.02.2009)
Published in Oncogene (12.02.2009)
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Impaired liver regeneration in mice lacking glycine N‐methyltransferase
Varela‐Rey, Marta, Fernández‐Ramos, David, Martínez‐López, Nuria, Embade, Nieves, Gómez‐Santos, Laura, Beraza, Naiara, Vázquez‐Chantada, Mercedes, Rodríguez, Juan, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C., Martínez‐Chantar, M. Luz, Mato, José M.
Published in Hepatology (Baltimore, Md.) (01.08.2009)
Published in Hepatology (Baltimore, Md.) (01.08.2009)
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Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury
Sanz, S, Pucilowska, J B, Liu, S, Rodríguez-Ortigosa, C M, Lund, P K, Brenner, D A, Fuller, C R, Simmons, J G, Pardo, A, Martínez-Chantar, M-L, Fagin, J A, Prieto, J
Published in Gut (01.01.2005)
Published in Gut (01.01.2005)
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Excess S‐adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis
Martínez‐Uña, Maite, Varela‐Rey, Marta, Cano, Ainara, Fernández‐Ares, Larraitz, Beraza, Naiara, Aurrekoetxea, Igor, Martínez‐Arranz, Ibon, García‐Rodríguez, Juan L., Buqué, Xabier, Mestre, Daniela, Luka, Zigmund, Wagner, Conrad, Alonso, Cristina, Finnell, Richard H., Lu, Shelly C., Martínez‐Chantar, M. Luz, Aspichueta, Patricia, Mato, José M.
Published in Hepatology (Baltimore, Md.) (01.10.2013)
Published in Hepatology (Baltimore, Md.) (01.10.2013)
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Loss of the glycine N‐methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice
Martínez‐Chantar, M. Luz, Vázquez‐Chantada, Mercedes, Ariz, Usue, Martínez, Nuria, Varela, Marta, Luka, Zigmund, Capdevila, Antonieta, Rodríguez, Juan, Aransay, Ana M., Matthiesen, Rune, Yang, Heping, Calvisi, Diego F., Esteller, Manel, Fraga, Mario, Lu, Shelly C., Wagner, Conrad, Mato, José M.
Published in Hepatology (Baltimore, Md.) (01.04.2008)
Published in Hepatology (Baltimore, Md.) (01.04.2008)
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Importance of a deficiency in S-adenosyl-l-methionine synthesis in the pathogenesis of liver injury
Martínez-Chantar, M. Luz, García-Trevijano, Elena R, Latasa, M. Ujue, Pérez-Mato, Isabel, Del Pino, Manuel M Sánchez, Corrales, Fernando J, Avila, Matias A, Mato, José M
Published in The American journal of clinical nutrition (01.11.2002)
Published in The American journal of clinical nutrition (01.11.2002)
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Conference Proceeding
Methionine Metabolism and Liver Disease
Mato, José M, Martínez-Chantar, M. Luz, Lu, Shelly C
Published in Annual review of nutrition (01.01.2008)
Published in Annual review of nutrition (01.01.2008)
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Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low‐density lipoprotein assembly in mice
Cano, Ainara, Buqué, Xabier, Martínez‐Uña, Maite, Aurrekoetxea, Igor, Menor, Ariane, García‐Rodríguez, Juan L., Lu, Shelly C., Martínez‐Chantar, M. Luz, Mato, José M., Ochoa, Begoña, Aspichueta, Patricia
Published in Hepatology (Baltimore, Md.) (01.12.2011)
Published in Hepatology (Baltimore, Md.) (01.12.2011)
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Fatty liver and fibrosis in glycine N‐methyltransferase knockout mice is prevented by nicotinamide
Varela‐Rey, Marta, Martínez‐López, Nuria, Fernández‐Ramos, David, Embade, Nieves, Calvisi, Diego F., Woodhoo, Aswhin, Rodríguez, Juan, Fraga, Mario F., Julve, Josep, Rodríguez‐Millán, Elisabeth, Frades, Itziar, Torres, Luís, Luka, Zigmund, Wagner, Conrad, Esteller, Manel, Lu, Shelly C., Martínez‐Chantar, M. Luz, Mato, José M.
Published in Hepatology (Baltimore, Md.) (01.07.2010)
Published in Hepatology (Baltimore, Md.) (01.07.2010)
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The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity
Bailly, Aymeric P., Perrin, Aurelien, Serrano-Macia, Marina, Maghames, Chantal, Leidecker, Orsolya, Trauchessec, Helene, Martinez-Chantar, M.L., Gartner, Anton, Xirodimas, Dimitris P.
Published in Cell reports (Cambridge) (01.10.2019)
Published in Cell reports (Cambridge) (01.10.2019)
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Obesity-Dependent Metabolic Signatures Associated with Nonalcoholic Fatty Liver Disease Progression
Barr, J, Caballería, J, Martínez-Arranz, I, Domínguez-Díez, A, Alonso, C, Muntané, J, Pérez-Cormenzana, M, García-Monzón, C, Mayo, R, Martín-Duce, A, Romero-Gómez, M, Iacono, O. Lo, Tordjman, J, Andrade, R. J, Pérez-Carreras, M, Marchand-Brustel, Y. Le, Tran, A, Fernández-Escalante, C, Arévalo, E, García-Unzueta, M, Clement, K, Crespo, J, Gual, P, Gómez-Fleitas, M, Martínez-Chantar, M. L, Castro, A, Lu, S. C, Vázquez-Chantada, M, Mato, J. M
Published in Journal of proteome research (06.04.2012)
Published in Journal of proteome research (06.04.2012)
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Liquid Chromatography−Mass Spectrometry-Based Parallel Metabolic Profiling of Human and Mouse Model Serum Reveals Putative Biomarkers Associated with the Progression of Nonalcoholic Fatty Liver Disease
Barr, Jonathan, Vázquez-Chantada, Mercedes, Alonso, Cristina, Pérez-Cormenzana, Miriam, Mayo, Rebeca, Galán, Asier, Caballería, Juan, Martín-Duce, Antonio, Tran, Albert, Wagner, Conrad, Luka, Zigmund, Lu, Shelly C, Castro, Azucena, Le Marchand-Brustel, Yannick, Martínez-Chantar, M. Luz, Veyrie, Nicolas, Clément, Karine, Tordjman, Joan, Gual, Philippe, Mato, José M
Published in Journal of proteome research (03.09.2010)
Published in Journal of proteome research (03.09.2010)
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HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis
Vázquez-Chantada, Mercedes, Fernández-Ramos, David, Embade, Nieves, Martínez-Lopez, Nuria, Varela-Rey, Marta, Woodhoo, Ashwin, Luka, Zigmund, Wagner, Conrad, Anglim, Paul P, Finnell, Richard H, Caballería, Juan, Laird-Offringa, Ite A, Gorospe, Myriam, Lu, Shelly C, Mato, José M, Martínez-Chantar, M Luz
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2010)
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Journal Article
Regulation of Mammalian Liver Methionine Adenosyltransferase
Corrales, Fernando J., Pérez-Mato, Isabel, Sánchez del Pino, Manuel M., Ruiz, Félix, Castro, Carmen, García-Trevijano, Elena Ruiz, Latasa, Uxue, Martínez-Chantar, M. Luz, Martínez-Cruz, Alfonso, Avila, Matías A., Mato, José M.
Published in The Journal of nutrition (01.08.2002)
Published in The Journal of nutrition (01.08.2002)
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Journal Article
Conference Proceeding
The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease
Guzmán, Carla, Benet, Marta, Pisonero-Vaquero, Sandra, Moya, Marta, García-Mediavilla, M. Victoria, Martínez-Chantar, M. Luz, González-Gallego, Javier, Castell, José Vicente, Sánchez-Campos, Sonia, Jover, Ramiro
Published in Biochimica et biophysica acta (01.04.2013)
Published in Biochimica et biophysica acta (01.04.2013)
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