Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis
Aykul, Senem, Maust, Jordan, Thamilselvan, Vijayalakshmi, Floer, Monique, Martinez-Hackert, Erik
Published in International journal of molecular sciences (06.08.2021)
Published in International journal of molecular sciences (06.08.2021)
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Journal Article
Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes
Aykul, Senem, Ni, Wendi, Mutatu, Washington, Martinez-Hackert, Erik
Published in PloS one (20.01.2015)
Published in PloS one (20.01.2015)
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Journal Article
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
Kempf, Henning, Olmer, Ruth, Haase, Alexandra, Franke, Annika, Bolesani, Emiliano, Schwanke, Kristin, Robles-Diaz, Diana, Coffee, Michelle, Göhring, Gudrun, Dräger, Gerald, Pötz, Oliver, Joos, Thomas, Martinez-Hackert, Erik, Haverich, Axel, Buettner, Falk F. R., Martin, Ulrich, Zweigerdt, Robert
Published in Nature communications (09.12.2016)
Published in Nature communications (09.12.2016)
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Journal Article
Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex
Townson, Sharon A., Martinez-Hackert, Erik, Greppi, Chloe, Lowden, Patricia, Sako, Dianne, Liu, June, Ucran, Jeffrey A., Liharska, Katia, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra, Grinberg, Asya V.
Published in The Journal of biological chemistry (10.08.2012)
Published in The Journal of biological chemistry (10.08.2012)
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Journal Article
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
Gooding, Sarah, Olechnowicz, Sam W. Z., Morris, Emma V., Armitage, Andrew E., Arezes, Joao, Frost, Joe, Repapi, Emmanouela, Edwards, James R., Ashley, Neil, Waugh, Craig, Gray, Nicola, Martinez-Hackert, Erik, Lim, Pei Jin, Pasricha, Sant-Rayn, Knowles, Helen, Mead, Adam J., Ramasamy, Karthik, Drakesmith, Hal, Edwards, Claire M.
Published in Nature communications (04.10.2019)
Published in Nature communications (04.10.2019)
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Journal Article
Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
Olsen, Oddrun Elise, Hella, Hanne, Elsaadi, Samah, Jacobi, Carsten, Martinez-Hackert, Erik, Holien, Toril
Published in Biomolecules (Basel, Switzerland) (29.03.2020)
Published in Biomolecules (Basel, Switzerland) (29.03.2020)
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Journal Article
Structural basis for potency differences between GDF8 and GDF11
Walker, Ryan G, Czepnik, Magdalena, Goebel, Erich J, McCoy, Jason C, Vujic, Ana, Cho, Miook, Oh, Juhyun, Aykul, Senem, Walton, Kelly L, Schang, Gauthier, Bernard, Daniel J, Hinck, Andrew P, Harrison, Craig A, Martinez-Hackert, Erik, Wagers, Amy J, Lee, Richard T, Thompson, Thomas B
Published in BMC biology (03.03.2017)
Published in BMC biology (03.03.2017)
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Journal Article
Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop
Aykul, Senem, Corpina, Richard A, Goebel, Erich J, Cunanan, Camille J, Dimitriou, Alexandra, Kim, Hyon Jong, Zhang, Qian, Rafique, Ashique, Leidich, Raymond, Wang, Xin, McClain, Joyce, Jimenez, Johanna, Nannuru, Kalyan C, Rothman, Nyanza J, Lees-Shepard, John B, Martinez-Hackert, Erik, Murphy, Andrew J, Thompson, Thomas B, Economides, Aris N, Idone, Vincent
Published in eLife (09.06.2020)
Published in eLife (09.06.2020)
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Journal Article
Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
Sako, Dianne, Grinberg, Asya V., Liu, June, Davies, Monique V., Castonguay, Roselyne, Maniatis, Silas, Andreucci, Amy J., Pobre, Eileen G., Tomkinson, Kathleen N., Monnell, Travis E., Ucran, Jeffrey A., Martinez-Hackert, Erik, Pearsall, R. Scott, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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Journal Article
Crystal structure of a potassium ion transporter, TrkH
Cao, Yu, Jin, Xiangshu, Huang, Hua, Derebe, Mehabaw Getahun, Levin, Elena J., Kabaleeswaran, Venkataraman, Pan, Yaping, Punta, Marco, Love, James, Weng, Jun, Quick, Matthias, Ye, Sheng, Kloss, Brian, Bruni, Renato, Martinez-Hackert, Erik, Hendrickson, Wayne A., Rost, Burkhard, Javitch, Jonathan A., Rajashankar, Kanagalaghatta R., Jiang, Youxing, Zhou, Ming
Published in Nature (London) (17.03.2011)
Published in Nature (London) (17.03.2011)
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Journal Article
How a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound Peptide
Mareeva, Tatiana, Martinez-Hackert, Erik, Sykulev, Yuri
Published in The Journal of biological chemistry (24.10.2008)
Published in The Journal of biological chemistry (24.10.2008)
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Journal Article
Fortilin interacts with TGF-β1 and prevents TGF-β receptor activation
Pinkaew, Decha, Martinez-Hackert, Erik, Jia, Wei, King, Matthew D., Miao, Fei, Enger, Nicole R., Silakit, Runglawan, Ramana, Kota, Chen, Shi-You, Fujise, Ken
Published in Communications biology (23.02.2022)
Published in Communications biology (23.02.2022)
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Journal Article
Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain
LIM, David, GREGORIO, G. Glenn, BINGMAN, Craig, MARTINEZ-HACKERT, Erik, HENDRICKSON, Wayne A, GOFF, Stephen P
Published in Journal of Virology (01.09.2006)
Published in Journal of Virology (01.09.2006)
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Journal Article
Receptor binding competition: A paradigm for regulating TGF-β family action
Martinez-Hackert, Erik, Sundan, Anders, Holien, Toril
Published in Cytokine & growth factor reviews (01.02.2021)
Published in Cytokine & growth factor reviews (01.02.2021)
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Journal Article
Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes
Martinez-Hackert, Erik, Anikeeva, Nadia, Kalams, Spyros A., Walker, Bruce D., Hendrickson, Wayne A., Sykulev, Yuri
Published in The Journal of biological chemistry (21.07.2006)
Published in The Journal of biological chemistry (21.07.2006)
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Journal Article