A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase
Martinez, Natalia J., Asawa, Rosita R., Cyr, Matthew G., Zakharov, Alexey, Urban, Daniel J., Roth, Jacob S., Wallgren, Eric, Klumpp-Thomas, Carleen, Coussens, Nathan P., Rai, Ganesha, Yang, Shyh-Ming, Hall, Matthew D., Marugan, Juan J., Simeonov, Anton, Henderson, Mark J.
Published in Scientific reports (21.06.2018)
Published in Scientific reports (21.06.2018)
Get full text
Journal Article
A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity
Yasgar, Adam, Titus, Steven A, Wang, Yuhong, Danchik, Carina, Yang, Shyh-Ming, Vasiliou, Vasilis, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Martinez, Natalia J
Published in PloS one (27.01.2017)
Published in PloS one (27.01.2017)
Get full text
Journal Article
Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells
Asawa, Rosita R., Danchik, Carina, Zakharov, Alexey, Chen, Yuchi, Voss, Ty, Jadhav, Ajit, Wallace, Darren P., Trott, Josephine F., Weiss, Robert H., Simeonov, Anton, Martinez, Natalia J.
Published in Scientific reports (13.10.2022)
Published in Scientific reports (13.10.2022)
Get full text
Journal Article
Identification of a G-Protein-Independent Activator of GIRK Channels
Zhao, Yulin, Ung, Peter Man-Un, Zahoránszky-Kőhalmi, Gergely, Zakharov, Alexey V., Martinez, Natalia J., Simeonov, Anton, Glaaser, Ian W., Rai, Ganesha, Schlessinger, Avner, Marugan, Juan J., Slesinger, Paul A.
Published in Cell reports (Cambridge) (16.06.2020)
Published in Cell reports (Cambridge) (16.06.2020)
Get full text
Journal Article
The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly
Martinez, Natalia J, Chang, Hao-Ming, Borrajo, Jacob de Riba, Gregory, Richard I
Published in RNA (Cambridge) (01.11.2013)
Published in RNA (Cambridge) (01.11.2013)
Get full text
Journal Article
Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity
Yasgar, Adam, Titus, Steven A, Wang, Yuhong, Danchik, Carina, Yang, Shyh-Ming, Vasiliou, Vasilis, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Martinez, Natalia J
Published in PloS one (15.05.2018)
Published in PloS one (15.05.2018)
Get full text
Journal Article
A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models
Martinez, Natalia J, Rai, Ganesha, Yasgar, Adam, Lea, Wendy A, Sun, Hongmao, Wang, Yuhong, Luci, Diane K, Yang, Shyh-Ming, Nishihara, Kana, Takeda, Shunichi, Sagor, Mohiuddin, Earnshaw, Irina, Okada, Tetsuya, Mori, Kazutoshi, Wilson, Kelli, Riggins, Gregory J, Xia, Menghang, Grimaldi, Maurizio, Jadhav, Ajit, Maloney, David J, Simeonov, Anton
Published in PloS one (29.08.2016)
Published in PloS one (29.08.2016)
Get full text
Journal Article
Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models
Martinez, Natalia J, Rai, Ganesha, Yasgar, Adam, Lea, Wendy A, Sun, Hongmao, Wang, Yuhong, Luci, Diane K, Yang, Shyh-Ming, Nishihara, Kana, Takeda, Shunichi, Mohiuddin, Earnshaw, Irina, Okada, Tetsuya, Mori, Kazutoshi, Wilson, Kelli, Riggins, Gregory J, Xia, Menghang, Grimaldi, Maurizio, Jadhav, Ajit, Maloney, David J, Simeonov, Anton
Published in PloS one (08.11.2016)
Published in PloS one (08.11.2016)
Get full text
Journal Article
The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans
Ow, Maria C, Martinez, Natalia J, Olsen, Philip H, Silverman, Howard S, Barrasa, M Inmaculada, Conradt, Barbara, Walhout, Albertha J M, Ambros, Victor
Published in Genes & development (15.09.2008)
Published in Genes & development (15.09.2008)
Get full text
Journal Article
A stele-enriched gene regulatory network in the Arabidopsis root
Ware, Doreen, Walhout, Albertha J M, Benfey, Philip N, Brady, Siobhan M, Zhang, Lifang, Megraw, Molly, Martinez, Natalia J, Jiang, Eric, Yi, Charles S, Liu, Weilin, Zeng, Anna, Taylor-Teeples, Mallorie, Kim, Dahae, Ahnert, Sebastian, Ohler, Uwe
Published in Molecular systems biology (18.01.2011)
Published in Molecular systems biology (18.01.2011)
Get full text
Journal Article
Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping
Walhout, Albertha J M, Vermeirssen, Vanessa, Deplancke, Bart, Barrasa, M Inmaculada, Reece-Hoyes, John S, Arda, H Efsun, Grove, Christian A, Martinez, Natalia J, Sequerra, Reynaldo, Doucette-Stamm, Lynn, Brent, Michael R
Published in Nature methods (01.08.2007)
Published in Nature methods (01.08.2007)
Get full text
Journal Article
Critical Assessment of Artificial Intelligence Methods for Prediction of hERG Channel Inhibition in the “Big Data” Era
Siramshetty, Vishal B, Nguyen, Dac-Trung, Martinez, Natalia J, Southall, Noel T, Simeonov, Anton, Zakharov, Alexey V
Published in Journal of chemical information and modeling (28.12.2020)
Published in Journal of chemical information and modeling (28.12.2020)
Get full text
Journal Article
Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity
Yang, Shyh-Ming, Martinez, Natalia J, Yasgar, Adam, Danchik, Carina, Johansson, Catrine, Wang, Yuhong, Baljinnyam, Bolormaa, Wang, Amy Q, Xu, Xin, Shah, Pranav, Cheff, Dorian, Wang, Xinran S, Roth, Jacob, Lal-Nag, Madhu, Dunford, James E, Oppermann, Udo, Vasiliou, Vasilis, Simeonov, Anton, Jadhav, Ajit, Maloney, David J
Published in Journal of medicinal chemistry (14.06.2018)
Published in Journal of medicinal chemistry (14.06.2018)
Get full text
Journal Article
High-Throughput Detection of Ligand-Protein Binding Using a SplitLuc Cellular Thermal Shift Assay
Sanchez, Tino W, Owens, Ashley, Martinez, Natalia J, Wallgren, Eric, Simeonov, Anton, Henderson, Mark J
Published in Methods in molecular biology (Clifton, N.J.) (2021)
Published in Methods in molecular biology (Clifton, N.J.) (2021)
Get more information
Journal Article